Plutella xylostella (diamondback moth): 105392640 Help Entry 105392640         CDS       T03915                                  Name (RefSeq) ryanodine receptor   KO K04962   ryanodine receptor 2 Organism pxy  Plutella xylostella (diamondback moth) Brite KEGG Orthology (KO) [BR:pxy00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pxy04040]     105392640    04990 Domain-containing proteins not elsewhere classified [BR:pxy04990]     105392640 Ion channels [BR:pxy04040]  Voltage-gated cation channels   Ryanodine receptor    105392640 Domain-containing proteins not elsewhere classified [BR:pxy04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    105392640 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  105392640 NCBI-ProteinID:  XP_048488160 LinkDB All DBs Position 31:2808124..2979086 Genome browser AA seq 5137 aa AA seqDB search MAEAEGGASEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIQDKNIPPDL SQCVFVIEQALSVRALQELVTAAGSETGKENLGKGTGSGHRTLLYGNAILLRHLNSDMYL ACLSTSSSQDKLAFDVGLQEHSQGEACWWTLHPASKQRSEGEKVRVGDDLILVSVATERY LHTTKENEVSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSS WSNEGQHNIVVYEGGSVMSQARSLWRLELARTKWAGGFINWYHPMRIRHITTGRYLAVND QNELYLVSREEATTASCAFCLRQEKDDQKVVLEDKDLEIIGAPIIKYGDSTVIVQHSESS LWLSYKSYETKKKGLGKVEEKQAILHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTK FINGLETLQENRRHSMFFATVNLAEMVMCLEDLINYFAQPDEDMEHEEKQNKFRALRNRQ DLFQEEGILNLILEAIDKINVITSQGFLAGFLAGDECGQSWEMISAYLYQLLAAIIKGNH TNCAQFANSNRLNWLFSRLGSQASGEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLL EKHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDYLLPGKNLLLQTQLVDHVSSVRPNIFV GRVEGSAVYQKWYFEVTMDHIEKTTHMMPHLRIGWANTTGYVPYPGGGEKWGGNGVGDDL YSYGYDGAFLWSGGRKTGVNRTHAEEPYIRKGDVIGCALDLTVPIINFMFNGVRVTGSFT NFNLEGMFFPVISCSSKLSCRFLLGGEHGRLRYAAPEGYSPLVECLLPQQILSLEPCFYF GNLAKRALSGPPLVQDDTAFVPMPVDTLTITLPSYIEQIRDKLAENIHEMWAMNKIEAGW MYGEHREDLHKIHPCLVPFERLPAAEKRYDIQLAVQTLKTILALGYYISLDKPPARIRNV RLPNEPFLQSNGYKPAPLDLSAVTLTPKMDELVEQLAENTHNLWARERIQQGWTYGLNED SDMHRSPHLVPYPKVDEAIKKANRDTASETVRTLLVYGYMLDPPTGEHEALLAEASKMKQ ADFRTYRAEKNYAVNSGKWYFEFEILTAGPMRVGWAHADMPPGMMLGQDENSWAFDGYNE EKVYVNSSESFGKQWAVGDVVGVFLDLIDNTISFSLNGELLMDALGGETTFADVQGDNFV PACTLGVGQKARLTYGQDVNTLKYFTTCGLQEGYEPFCVNMKRDVTHWYTKDQPIFENTD EMADTRIDVTRIPAGSETPPCMKISHNTFETMEKANWEFLRLSLPVICHAEFIDENEKAR RWVEIKERQQALMKEAAEAQMPAHIDQIMRSGFTMNDIKGLHRDYDDGQEEPSNSKMKRL PSRPPRKGSLSRGVTIQNYSLQPGQQNGMHRTASEMEMSKYESGAQSVTDDKKDKRGRSP FKFFSRSKRGESGDRKSRKSKTPDPFSDAEVSPERAAPRRPNPQIRVSQANQRYEKNQSR QNLYGSQGGGLNNGNTNLQVNTPPVERKQMTGGALSGATTETVGNEIFDAECLKLINEYF YGVRIFPGQDPTHVYIGWVTTQYHLHSKDFNQSKVTKSSVIITDDYDRVIRSVNRQSCYM VRADELYNEVMAEAVGKGASQGMFVGCSVDTSTGTVAFTCEGKETSFRFSMEPETKLFPA IFVEATSKEILQIELGRSLHSLPLSAAVLPTSDKHVIPQFPPRLKVQCLKPHQWARVPNQ SLQVHALKLSDIRGWSMLCEDAVSMLALHIPEEDRCIDILELIEMDKLLSFHSHTLTLYA ALCYQSNYRAAHALCQHVDQKQLLYAIQSQYMSGPLRQGFYDLLIALHLESHATTMEVCK NEYVIPLGPELKALYEEPEMGHSLRSLQTESVRPMMKMTDIAESINEISNLYSPYFPLDV VREFVMQALAEAVETNQVHNRDPVGGSNENLFLPLIKLVDRLLLVGMMRDEDVEKLLIMT NPETWDPTFDKEGKDEHKKGLLHMKMAEGAKLQMCYLLHHLNDIQLRHRVEAIIAFAHDF VGDLQADQLRRYVEIKQSDLPSAVAAKKTREYRCPPREQMNAILSFKHLEEDDKENIPCG EDLIARMNDFHQALMAHVSLMALQEPEVEENPEALNKPGAIGKLYNIINTVKELDEEPKA IEEPVKKTPEEKFRKVLIQTIVSWAEESQIETPKLVREMFSLLVRQYDAVGELVRALEKT YVINAKTKLDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNHTFFQHPDLIRVL RVHENVMAVMMNTLGRRAQAQSDATPNQPAAEEKVGPHIQGVPKTGKKDTSHEMVVACCR FLCYFCRTGRQNQKAMFDHFDFLLENSNILLSRPSLRGSTPLDVAYSSLMENTELALALR EHYLEKIAVYLSRCGLQSNSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENAN LVIRLLIRRPECLGPALRGEGEGLLKAIVDANKMSEKIADRRKLHEEVGQEDVAFSHPLP ESDEDEDYIDTGAAILNFYCTLVDLLGRCAPDASVIALGKNESLRARAILRSLVPLEDLQ GVLSLRFTLNNPAMGEERPKSDMPSGLIPGHKQSIVLFLERVYGIETQELFYRLLEEAFL PDLRAATMLDRNDGCESDMALSMNRYIGNSILPLLIKHANFYNEAENYGSLLDATLHTVY RLSKNRMLTKGQREAVSDFLVALTSAMQPSMLLKLLRKLTVDVSKLSEYTTVALRLLTLH YERCAKYYGSTGGQGVYGASSDEEKRLTMMLFSNIFDSLSKMDYEPELFGKALPCLIAIG CALPPDYSLSKNYDDEFYGKEQQTTGGPDNPQYNPQPINTSSVALNNDLNTIVQKFSEHY HDAWASRKIENSWVYGENWSDSQKAHPRLKPYNMLNDYEKERYKEPVRESLKALLAIGWS VEHSEVDIPSTNRSSMRRQSKSGGRPVDVVTDSATPFNYNPHPVDMTNLTLSREMQNMAE RLAENAHDIWAKKKKEELTVNGGGIHPQLVPYDLLTDKEKKKDRERSQEFLKYLQYQGYK LHRPSKATQSETEQTATGVAIELRFAYSLLEKLIQYIDRATINMKMLKPSTTFSRRSSFK TSTRDIKFFSKVVLPLMEKYFSTHRNYFIAVATATNNVGAASLKEKEMVAALFCKLASLL RSRLTAFGPDVRITVRCLQVLVKGIDAKSLVKNCPEFIRTSMLTFFNNVADDLGHTIHYL QDGKYSHLRGTHLKTSTSLGYINGVIMPVLTAMFDHLANCEYGADLLLDEIQVASYKMLG SLFTLGTDSTLTHDRKYLKTEIERHKNALGSCLGAFSSTFPVAFLEPHLNKHNQFSLLNR IADHSLEAQDVMARMEQSMPTLETILGLVEQFVDSDKTYSDSPHVIDVVLPLLCSYLPFW WAQGPDNVTPSGGNHVTMVTADHMNQLLKNVLKLIKKNIGNENAPWMTRIATYTQQIIIN SSEELLRESFLPLAERVRKRTDNMFHKEESLRGFIKSSTDDTSQVESQIQEDWQLLVRDI YSFYPLLIKYVDLQRNHWLRNNVNEAEELYNHVAEIFNIWSKSQYFLKEEQNFISANEID NMVLIMPTATRRVTTVVDGAPQGGGKVKKKKKHRDKKRDKDKEVQASLMVACLKRLLPVG LNLFAGREQELVQHCKDRFLKKMTEQDVAEFAKTQLTLPDKIDPADEMSWQHYLYSKLGS KSKTTTAMETAAENKAKIIDDTVERIVAMSKVLFGLHMIDHPQQMSKNVYRSVVSIQRKR AVIACFRHLPLHQLPRHRACNIFSRTYYELWLEEENIGQEVMIEDLTQSFEDAELKKSDV EAEGEGKPDPLTQLVTTFCRGAMTERSGALQEDPLYMSYAHIIAKSCGEEEEEGGEEEEE GAGEAEGEEEGGASIHEQEMEKQKLLFHQARLADRGVAEMVLLHISASKGVPSDMVMKTL QLGISILRGGNIDIQMGMLNHLKDKKDVGFFTSIAGLMNSCSVLDLDAFERNTKAEGLGV GLEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLL RLQESIMDFYWHYSSKELIDPAGKANFFKAIGVASQVFNTLTEVIQGPCTQNQQALAHSR LWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQM VDTLVESASNVELILKYFDMFLKLKDLTTSASFAEIDANNDGWVLPKDFKEKMEQQKSYT PEEIEFLLACCETNHDGKLDYIGFCDRFHEPAKEIGFNLAVLLTNLSEHMPNEPRLARFL ETAGSVLNYFEPFLGRIEIMGGSKRIERVYFEIKESNIEQWEKPQIKESKRAFFYSIVTE GGDKEKLEAFVNFCEDAIFEMTHASGLMADAEEAGGGPKNREAAYMYMGDDDDDSRGKDP FRRGLQSVKDGIATAFSSLSPANIKQKIADMSQMPPQELAVGFFKMFFYLFYYIGYGALV VVRYIFGVLLGLMRGPQVEEPPPEPTEEEKIGPSRHLPALSATDDQGQMAVSAFGLDITK EDNGQVQIKPHESPGTSSPSSGEEAETAEDGEHSGDEPQPPSLIDLLGGEQAKKQAQERI EAQAAQQAAMSAIEAESKKAVQAPAPSALSQVDLSQYTRRAVSFLARKFYTLKYVALVLA FCINFVLLFYKVSTLDAEPGEGSGIGDIISGSGSGSGSGSGDGGSGEEDEDPIELVHIDE DYFYMEHVIKIAALLHSIVSLAILIGYYHLKVPLAIFKREKEIARKLEFDGLYIAEQPED DDLKSHWDKLVISAKSFPVNYWDKFVKKKVRVKYSETYDFDSISNMLGMEKTAFATQEDE GRGFFHYILSIDWRYQVWKAGVTITDNSFLYSLWYFSFSVMGNFNHFFFAAHLLDVAVGF KTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYVQEEDDDINRNCHDMLT CFVFNLYKGVRAGGGIGDELEPPDGDDSEAWRIVFDITFFFFIIVILLAILQGLIIDAFG ELRDQLESVKEDMESNCFICGINKDYFDKVPHGFDTHVQREHNLANYMFFLMHLINKPDT EYTGQETYVWNMYTQRCWDFFPVGDCFRKQYEDAMGE NT seq 15414 nt NT seq  +upstreamnt  +downstreamnt atggcggaagcggaagggggcgcgagcgagcaggatgatgtttcattccttcgcacggaa gacatggtgtgcctgtcctgcacggccacgggagaacgagtgtgtctcgcggcggagggc ttcggcaaccgacactgcttcctcgagaacatacaggacaagaacataccgccggatctg agccagtgcgtgtttgttattgaacaggctctgtcagtgcgagcgttgcaagaattggtg actgctgcaggttccgaaactgggaaagaaaatttaggtaaaggcaccggttccggacat aggacgttgctttacggcaatgccatcctacttcggcatctcaacagtgacatgtaccta gcctgtctctccacatcatcgtcccaggacaagctggccttcgatgtgggtcttcaggag cactctcagggagaggcgtgctggtggaccctgcacccggccagtaagcagagatctgag ggtgagaaggtgcgtgtcggagacgacctgatcctcgtgtctgtcgctactgagcggtac ttgcacacaacaaaagagaacgaagtctccatcgtgaacgcatcgttccacgtgacacac tggtccgtgcagccgtacgggaccggcatatcccggatgaagtacgtcggatacgtgttc gggggcgacgtgttgcgtttcttccacggaggcgacgaatgtctcactataccgagcagt tggtccaacgagggacaacacaacatcgtggtctacgaaggaggttcagtgatgtctcaa gctcgatctctatggaggttggaactagctaggacgaagtgggctggggggttcatcaac tggtaccacccaatgaggatcaggcatatcactactggccggtatttggctgttaacgac cagaatgaactgtatttggttagcagagaggaagccacaacggcctcctgtgccttctgc ctccgccaagagaaggatgaccagaaagtagttctagaagacaaagacctggagatcatc ggcgcccccatcattaagtatggagactccactgtcattgtgcagcactcggagtctagt ttgtggctgtcttataagtcctacgaaaccaagaaaaaaggcctgggcaaagtggaagaa aagcaagcgatccttcacgaagaaggcaagatggacgacggcctggacttctcccgctcg caggaggaggagtcgcgcaccgcgcgcgtcatcagaaagtgctcgtcgctgttcaccaag ttcatcaatggcctagagacccttcaggaaaaccggcgccattcaatgttcttcgcgacg gtgaacctggcggagatggtgatgtgtctcgaggacctcatcaactacttcgcacagccc gacgaggatatggagcacgaagagaagcagaacaagttccgcgcgctgcgcaaccgacag gacctgttccaagaggagggcatcctcaatctgattctggaggcgattgacaagattaat gttattacgtcgcagggtttcctggcgggtttcctggccggcgatgagtgtggccagagc tgggagatgatctccgcgtatctgtaccagctgttagcggcaatcataaagggcaaccac accaactgtgcccagttcgccaactcgaaccggctcaactggctgttctctcgactggga tcgcaggcttcgggggagggcacgggcatgttggatgtactgcattgtgtgctgattgat tcacctgaagctctgaatatgatgagggacgagcacataaaagtcatcatatccctccta gagaagcacggtcgagaccccaaagtcctggacgtcttatgttccctgtgcgtgggcaac ggcgtcgcggtgcgctcgtcacagaacaacatatgcgactatctgctgccggggaagaac ttgctgttgcagacgcagctggtcgatcatgtgtctagcgtccgcccgaacatcttcgtg ggaagggtagaaggctctgccgtgtaccagaagtggtacttcgaggtgacgatggaccac atcgagaagaccacccacatgatgccgcatctgcgcatcggctgggctaatactactggc tacgtcccatacccagggggcggtgaaaagtggggcggcaacggagtgggcgacgatctc tactcatacggatacgacggcgctttcctctggtctggggggcggaaaactggcgtcaac aggactcatgctgaagagccgtatattaggaagggtgacgtgatcggttgcgccctcgac ctgacggtgccgataatcaactttatgttcaacggagtaagggtcacggggtcgttcacc aacttcaacttggagggcatgttcttccctgttatcagctgttcgagcaagttgagttgc cgtttcctcctcggcggggagcacggtcgccttcgctacgccgctcctgaagggtactcg cctcttgtagagtgtctactgcctcagcagatacttagcttggagccttgcttctacttc ggtaacttggctaaaagggcgttgtcgggaccaccgctagttcaagatgacacggccttc gttcctatgcctgttgacacgcttacgatcacactgccttcttacattgagcaaatcaga gacaagttggctgaaaacattcatgaaatgtgggcgatgaataagatcgaggcaggctgg atgtacggcgagcatcgtgaggacttgcacaagatacacccgtgtctggtgccgtttgaa cgcctacctgctgctgagaagcgatacgatatacagctggctgtgcagactttgaagaca atcctagctctgggctactacatcagcttggacaagccgccagcgagaattcgcaacgtg cgcctgccgaatgaaccattcttgcagtcaaacggctacaaaccagcgcctctagacctc agcgctgtcaccctgacacccaaaatggacgagctcgtggaacaactggcggaaaacaca cacaatctgtgggccagagagaggatccaacaagggtggacgtatgggcttaatgaggat tccgacatgcaccgctcaccccatctagtcccgtaccctaaagtggacgaggcgatcaag aaagccaacagagacaccgcttcggagaccgtccggactctattagtgtatggttatatg ctggacccgcctactggcgagcatgaagccctcctagccgaagcttccaagatgaagcaa gcagacttcagaacgtatagagctgagaaaaactacgcggtcaactcgggcaagtggtac ttcgagtttgaaatactcacagctgggcctatgcgggtcggctgggcccatgctgacatg ccaccaggtatgatgctcggacaagacgagaactcttgggcttttgatggatacaatgag gagaaagtttacgtgaacagctccgagtcgttcggcaagcagtgggccgtgggggacgtg gtgggggtcttcctcgacctcatcgataacaccataagtttctctctaaacggagagttg ctaatggatgccctcggaggtgagaccacatttgcagatgttcagggggacaacttcgta ccggcttgtaccctgggcgttggacagaaggccagattaacttacggtcaagatgtgaat actttgaaatacttcacgacgtgtggtctgcaagaaggctatgagccgttctgtgtcaac atgaagcgtgacgtcacgcactggtacacgaaggaccagcccatattcgagaacacggac gaaatggccgacaccaggatcgacgtcaccaggatacccgctggctctgaaacacccccc tgcatgaagatctcacacaacacgttcgagacgatggagaaggcgaactgggagttcctg cgactatctctgccggtcatctgtcatgctgagttcattgatgagaacgagaaagcccgt cgctgggtggagatcaaagagcgccaacaagccctgatgaaggaggcagctgaagcgcag atgccggcgcacatagaccagatcatgaggagtgggttcactatgaacgatatcaaaggt ctacatcgcgactatgatgatggtcaagaggagccaagcaactccaaaatgaaacgtctg ccgtcgcggcccccgcgaaaaggatccctaagtcggggcgttacgattcaaaattactcg ttgcaaccaggtcaacagaacggcatgcatcgcactgccagtgagatggaaatgtcgaag tatgaatctggcgctcaaagtgtcactgatgataagaaagacaaaaggggaagatctcct ttcaaattcttttcaaggagcaaacgtggggagagtggcgatcgcaagtcgcgtaaatca aaaacgcctgatccgttcagtgacgccgaagtgtcgcctgaaagagccgcgccgcgccgg cccaacccacagattagagtgtctcaggcgaatcagagatatgaaaagaatcagagcagg caaaatttgtatggcagccaagggggtggcttgaataatggcaacacaaacctgcaagtg aacacgcctccagtggaacgcaagcagatgaccggtggtgccctctctggagcgacgacg gagactgtcgggaatgagatattcgacgcggagtgcttgaaactgatcaatgaatacttt tatggtgttcgcatcttccccggtcaagacccaacccacgtgtacatcggctgggtgacc actcagtaccacttgcactcgaaggacttcaaccagtcgaaggtcaccaagtcttccgtc atcatcactgacgattatgatagagttatacgcagtgtgaaccgtcagtcgtgctacatg gtgcgagctgatgagctctacaacgaggtgatggccgaagctgttgggaagggagcgtct cagggtatgttcgtgggttgttccgtggacacttcgaccggcacagtcgccttcacttgt gaaggaaaggagaccagtttcagattcagtatggaaccagaaacgaagctattcccagcc atcttcgtggaagcgacttccaaggagattctgcagatagagctaggcaggtccctacac agcctgccgctcagtgccgccgtcctgcccactagcgacaaacatgtcataccacagttc ccaccgcgtctaaaggtgcaatgcttgaagcctcaccaatgggccagggtaccaaaccaa tctctgcaagtgcatgcgttgaagctatcagacatccgcggatggtctatgctgtgtgaa gatgcagtttctatgctggctctacatattccagaggaagaccgctgcatcgacatctta gagctgatagagatggacaagctgctgagcttccactcgcacaccctcaccctgtatgcg gctttgtgctaccagagtaactatagagcggcgcacgctctctgccaacatgtcgaccaa aagcaacttctctacgccatccagtctcagtacatgtcggggccgcttcgccagggcttc tacgaccttctcatagcgttgcatctagagtcgcacgccaccaccatggaggtgtgcaag aacgaatacgtgatcccgttgggcccggagctgaaggcgctgtatgaggagccggagatg ggccacagtctgcggagcctccagaccgagagtgtgaggcctatgatgaagatgactgat attgctgaaagcataaacgagataagcaacctctactcgccgtacttccctctcgatgtg gtccgtgagttcgtgatgcaagccctggctgaagcggtggagactaatcaagtgcataat agagatcctgtgggagggagcaatgagaaccttttcctgccgctcatcaagctggtggac cgtctgctgctggtgggcatgatgcgcgacgaggacgtggagaagctgctcatcatgacc aacccggagacctgggaccccaccttcgataaagaaggcaaagacgagcacaaaaaaggt ctcctccacatgaaaatggcggaaggggctaaactacaaatgtgctatttactgcaccac ctcaacgacatacaactacggcacagagttgaggccatcatcgcgttcgcccatgacttt gtcggggatttacaggccgatcagttgagacgttacgtagagatcaaacagtcggacctg cccagcgccgtcgcggccaagaagaccagagaataccgctgtccaccgcgggaacaaatg aacgctattctgagcttcaagcacttagaagaggacgacaaagagaacatcccgtgcgga gaagacctgatagccaggatgaacgacttccaccaggcgctcatggctcatgtgtcgctg atggcgttgcaggaacctgaagttgaggaaaacccagaggccttgaacaagcctggagcg atcggcaagctgtacaacatcatcaacaccgtcaaggaattggatgaagagcctaaagcg atagaagagccagtaaagaagacccctgaggagaagttccgcaaagtgctgatccagacc atcgtgtcgtgggccgaggagtcgcagatcgagacgcccaaactcgtcagagagatgttc agtctcctagtccgccaatacgacgccgtcggcgagctggtccgagccctagagaagacg tacgtcatcaacgcgaagaccaagttggacgtggcggagatgtgggtggggctgagccag atccgcgccctgctccctgtgcagatgagccaggaggaggaggagctcatgcggaagaga ctctggaaacttgtcaacaaccacacattcttccagcatcctgatttgatcagagtcctc cgcgtccacgagaacgtgatggccgtgatgatgaacactttaggccgccgtgcgcaggcg cagtccgacgccacgcccaaccagccggcggctgaggagaaggtgggtccgcacattcag ggcgtgccgaagacggggaaaaaggacacgtctcacgaaatggtggtcgcttgttgccgg ttcttgtgctacttctgtaggactgggcggcagaatcagaaggccatgttcgatcacttc gactttttgttggaaaactccaacattctgctgtcgcggccatctttaagagggtccacg ccgctagatgtcgcttattcgagtttgatggagaatactgagctggctttggctttgaga gaacattacctcgagaagatagccgtctacctctcgcgctgcggcctgcagtccaactcg gagctggtggagaaggggtacccggacctgggctgggacccggtggagggggagcggtat ctggacttcctgcgcttctgtgtctgggtgaacggagagagtgtggaagagaacgcgaac ctggtgatccggctgctgatccgccgccccgagtgtctcgggcccgcgcttaggggcgag ggcgaaggcctacttaaggccatcgtggacgccaacaagatgagtgagaagatagcggat cgcaggaaactgcatgaagaagtcggccaggaggacgtcgcattcagccacccgctcccc gagtcagacgaggatgaagactacatcgacactggggcggccatcttgaatttctactgc acactggttgacttgctgggacgatgcgcgccggatgcctctgttattgctcttggcaag aacgagtcgctccgcgcgcgcgccatcctgcgctcgctggtgccgctcgaggatctacag ggtgttctgagtctgcggttcacgctgaacaaccccgccatgggggaggagaggcctaag tctgacatgccatcaggcctgatcccggggcacaagcagagcatagttctgttccttgag cgagtctacggcatcgagactcaggagctgttctaccgactgctggaggaggctttcttg cctgatttgagggccgccaccatgctagataggaacgacggctgcgaatcggacatggct ctctcgatgaatcgatacatcggcaactcgattctgcccctactgatcaaacacgccaac ttctacaacgaagccgagaactatggcagcctgttggacgccactctgcacactgtttat aggctctccaaaaaccgcatgttaaccaagggtcaacgtgaggcggtgtcagacttcctg gtagccttgacttctgccatgcaaccttccatgttgctgaaactgctgaggaaactcacg gttgacgtgtcgaagctgagcgagtatactactgtcgctttacggctgctaaccctccac tacgagcgctgcgcaaaatactacggcagtacagggggccagggcgtgtacggagcctcc tccgacgaggagaagcgactcaccatgatgctgttcagcaacatcttcgactccctgtcc aagatggactacgagccggagctgtttgggaaggcgttgccgtgtttgattgctataggt tgcgcgctgccgcctgactactctctttccaagaactacgatgatgagttctacggaaaa gaacagcagactacaggcggtccagacaaccctcagtacaacccacaacccatcaacacg tcttcagtggctttgaacaacgacctcaacactattgtgcagaagttctctgaacactac cacgacgcttgggcttccaggaaaatcgagaacagctgggtgtacggtgagaactggtcc gacagccagaaggctcacccgcggctgaagccctacaacatgctcaatgattacgagaaa gagcgctacaaagagcctgtccgtgagtctctgaaggccctcctcgccatcggctggtcc gtcgagcactctgaagtggacattccgtccactaatcgtagctccatgaggcggcagagc aagagtggagggcgccctgtggacgtcgtgacggactcagcaacacccttcaactacaac cctcacccagtggacatgacgaacctcactctctcgagagagatgcagaacatggctgag aggttggctgagaacgctcacgacatctgggcgaagaagaagaaggaggaacttacggtt aatggcggcggcatccaccctcaactagtgccctacgacttactaaccgacaaagaaaag aagaaagatcgagaacgatctcaagagttcctcaaataccttcaataccaaggctacaag ctacacagacccagcaaggccacacaaagcgaaacagaacagaccgctacgggggtagca atagagttgagattcgcgtattcgttgctggagaagttgatacagtatatcgatagagcg acgattaatatgaagatgctgaaaccgtctacgactttcagtcgcaggtccagttttaag actagcacgagggatattaagttcttctctaaggtggtcttacctttgatggagaaatat ttctctactcatcgcaactacttcatagcggtggcgacggccacgaacaatgtcggcgcg gctagtttgaaggagaaagaaatggtggctgctttgttttgtaaactggccagtttattg agatctcgcctcacagccttcggccccgacgtccgcatcacagtccgctgcctccaagtc ctcgtcaagggcatcgacgccaagtcgctggtgaagaactgccccgagttcatccgcacg tccatgctcacgttcttcaacaacgtcgccgacgacctgggacacaccatacactatttg caggacggcaagtactctcacctgcgcggcacgcacctcaagacatccacgtcactgggc tacatcaacggagtcatcatgccggttctgacggccatgttcgaccatctggccaattgc gagtatggggcggatttgttgctggacgagatccaagtggcatcgtacaagatgctgggg tctctgttcacgctgggcacggactcgacgctcacacacgacaggaagtatcttaagaca gagatcgagagacacaagaatgcgttgggttcctgtctaggtgcgttcagctccacgttc cctgtggccttcctggagccacatctcaacaagcacaaccagttctcactgctgaaccgg atcgccgaccactcgcttgaagctcaagacgtaatggcgcgcatggagcaaagcatgccg acgctcgaaacgatcctcggattagtcgagcaattcgtcgactcggacaagacttattca gactcgcctcacgtcatcgatgtggtgctgccgctgctgtgctcgtacctgccgttctgg tgggcgcagggacccgacaacgtcacgcccagcggcggaaaccacgtaacaatggtgaca gccgaccacatgaaccaacttctcaagaacgtgctcaaactaattaagaagaacattggc aacgaaaacgctccctggatgactcgcatagctacctacacgcaacagatcattattaat agttctgaggaactgttgcgtgagagcttcctgccgttggccgagagggttcgcaagagg acggataacatgttccataaggaggagagcttgagagggtttattaagtcctcaacagac gacacgtctcaagtggagtcccagatccaagaagactggcagctgctggtcagagacatc tactccttctacccgctgctcatcaagtacgtggacctgcagcggaaccactggctccgg aacaacgtcaacgaggcggaagagttgtacaaccacgtggcagagatcttcaacatctgg tccaagagccagtacttcctgaaggaggaacagaacttcatatcggccaacgaaattgac aacatggtgctcattatgccgactgccacccgtcgagtcaccactgtcgtcgatggagcc cctcagggcggcggcaaggtcaagaagaagaagaagcaccgcgacaagaagcgcgacaag gacaaggaggtgcaagcctcgctgatggtggcgtgtctcaagcggctgctgcccgtcggg ctgaacctgttcgcgggacgagagcaggagctcgtgcagcattgcaaggacaggttcttg aagaaaatgaccgagcaagatgtggccgagttcgctaaaacgcagctgactctcccggac aagatcgacccggccgacgagatgtcctggcaacactacttgtacagtaaactgggctcc aagtctaaaaccaccactgccatggaaactgcagctgagaacaaggcgaaaatcattgat gatactgtcgagagaattgtggccatgagcaaagtactgtttggactgcacatgattgac cacccgcaacaaatgagtaagaacgtctatcggtcagtcgtatcgattcaacgcaagcgc gccgtcatagcttgcttcagacatctgccactgcatcaacttccaagacatcgtgcctgc aacatattctcgaggacctactacgagttgtggctggaggaagagaatattggacaagag gtcatgattgaggaccttactcaatcattcgaagacgcggagctgaaaaagagcgacgtg gaagcggagggcgaaggcaagcccgaccctctgacccagctggtcaccaccttctgtagg ggcgccatgactgaacgatccggggctttacaggaagaccccctgtacatgtcgtacgcg cacatcatcgccaagtcctgcggggaagaagaagaggaagggggggaggaggaggaggag ggcgcgggcgaggccgagggcgaggaggaggggggagctagtatacatgaacaagagatg gaaaaacagaagctactgttccaccaagcgagattggccgaccgtggcgtggcagaaatg gtcctactacatatttctgcttcgaaaggtgtgccaagcgatatggtgatgaagacacta caactgggtatatctattctgagaggcggtaacattgatatacagatgggtatgctgaat cacctcaaagacaagaaagacgtaggattcttcacatctattgctggtctgatgaactcc tgttctgtactggacttggatgcctttgaaaggaacaccaaggctgaaggtctcggcgtg ggtctagaaggcgcggccggagagaagaacatgcacgacgcagagttcacgtgcgcactg ttccggttcatacagctcacttgtgaaggacacaatttggaatggcagaactacctgcgc acgcaagccggcaacacgacgacagtgaacgtggtgatctgcaccgtggactacctgctg cggctgcaggagtccatcatggacttctactggcactactccagcaaggaactaatagac ccggccggcaaggcaaacttcttcaaggccatcggcgtcgcgtcgcaggtgttcaacaca ctcactgaggtcatccaggggccctgcacgcaaaaccaacaggcgctggctcactctagg ttgtgggacgcggtgggcggtttcctcttcctcttctctcacatgcaggacaagctgtcc aagcactcgtcccaagtggacctgctgaaggagctgctgaacctgcagaaggacatgatc accatgatgctgtccatgcttgaggggaacgtggttaacggcacaatcggtaaacagatg gtggacacactagtagagtccgcttccaacgtggagctaatcctgaaatacttcgacatg ttcctgaagctgaaagacctgaccacgagcgccagtttcgctgaaattgacgctaacaac gacggatgggtgctacctaaggatttcaaggagaagatggaacagcagaagagttatacg cccgaagagatcgagttcctcctcgcctgctgcgaaaccaatcacgacggcaaactggac tacatcggcttctgcgaccgcttccacgagcccgccaaggagatcgggttcaacctggct gttctactcaccaacttgtccgagcacatgcctaatgaacccagactggcacgattcctg gagacggccggctcagtgctcaactacttcgagccgttcctcggtcgcatcgagatcatg ggcggctccaagcgcatagagagggtgtacttcgagatcaaggagtccaatattgagcag tgggagaagccgcagattaaggaatccaaacgagcattcttctacagtatagtaacagag ggaggtgacaaggaaaaactagaagcgttcgtgaatttctgcgaagacgccatctttgaa atgactcacgcttccggtctaatggcggatgcggaagaggcggggggcgggcccaagaat agggaggctgcttatatgtatatgggcgatgatgatgatgacagtcgcggcaaagaccca ttccgtcgcggcctgcagtccgtgaaggacggcatcgccacggcattctcgtccttatct ccagcaaacataaagcagaaaatcgcagacatgtcccagatgccccctcaagagttggct gtcggtttcttcaagatgttcttctatttgttctactatattggatacggagctttggtt gttgttaggtacatattcggcgtgctactcggcctgatgcgaggtcctcaagtggaggaa ccacctccagaacccacggaagaggagaaaatcggtcccagcagacacctgccggcactg tcagcgacagacgatcaggggcagatggcggtgtcggccttcggattggatatcactaag gaagataatggacaggtgcagataaagccccacgagtccccgggcacgtcgtcgccgtcc tctggcgaagaagcagagacggccgaggatggagagcacagtggggacgagccgcagcca ccctcgctgatagacctgctgggaggtgaacaagccaagaagcaagctcaggagaggata gaggcgcaagcggcgcagcaagccgccatgtcagccattgaggctgagagcaaaaaggca gtgcaagcgcccgccccctcagccctgtcccaggtggacctctcccagtacacgcggcgc gccgtgtccttcctcgcgaggaagttctacaccttgaagtatgtggcgctggtgctggcc ttctgcatcaactttgtgctgctgttctataaggtatccaccctggacgctgagcctggt gaagggtccggaattggagacatcatcagcggctccgggtcagggtctggttccggcagc ggcgacggaggcagcggtgaagaagacgaagatccgatagagctggtgcatatagacgag gattacttctacatggaacacgtcatcaagatagctgcgttactgcattctatagtatcg ctggctatactgatcgggtactaccatttgaaggtcccgctcgccattttcaagcgtgag aaggagatagctcgtaaactggagttcgatggcctctacattgcggagcagccagaagac gacgacttgaagagccactgggacaagcttgttatatctgccaagtcgttcccagtgaac tactgggataagttcgtgaagaagaaggtccgcgtcaagtactcggagacttacgacttc gactccatctccaacatgctcggcatggagaagaccgcctttgcgacgcaggaagatgag ggcagagggttcttccactacatcctaagcatagactggcgctaccaagtgtggaaggcg ggcgtcacgatcacagacaactcgttcctgtactctctatggtacttctcgttctctgtg atgggcaacttcaaccacttcttcttcgccgctcatctgttggacgtggccgttgggttc aagacgctgaggactatcttgcagtctgtcacgcataacgggaaacagctggtcctgacg gtgatgctgctcaccatcatcgtgtacatctacacggtcatcgccttcaacttcttccgc aagttctacgtgcaggaggaggatgatgacattaataggaactgccatgatatgttgacg tgcttcgtattcaacctttacaagggcgtgcgcgcgggcggcggcatcggagacgagttg gagcctccagacggcgacgactcggaggcgtggcggattgtctttgatattaccttcttc tttttcatcatcgtcatcctgttggctattcttcagggtttgatcatcgacgcgttcgga gagctccgtgaccagttggagtccgtcaaagaagatatggagtccaactgcttcatatgt ggaatcaacaaggactactttgataaggtcccacacggattcgacacgcacgtgcagaga gaacacaacctggccaactacatgttcttcctcatgcatctcatcaataagccggatacg gagtatactggtcaagagacgtacgtgtggaacatgtacacgcagcgttgctgggacttc ttccccgtcggagactgtttcaggaagcagtatgaggacgccatgggagagtag

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