Pyrococcus sp. NA2: PNA2_1343
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Entry
PNA2_1343 CDS
T01487
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pyn
Pyrococcus sp. NA2
Pathway
pyn00290
Valine, leucine and isoleucine biosynthesis
pyn00660
C5-Branched dibasic acid metabolism
pyn01100
Metabolic pathways
pyn01110
Biosynthesis of secondary metabolites
pyn01210
2-Oxocarboxylic acid metabolism
pyn01230
Biosynthesis of amino acids
Module
pyn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PNA2_1343
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PNA2_1343
Enzymes [BR:
pyn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PNA2_1343
4.2.1.35 (R)-2-methylmalate dehydratase
PNA2_1343
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Paralog
Gene cluster
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Motif
Pfam:
Aconitase
AcnX
LolA_like
Motif
Other DBs
NCBI-ProteinID:
AEC52258
UniProt:
F4HIF8
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All DBs
Position
complement(1230098..1231369)
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AA seq
423 aa
AA seq
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MGMTIAEKILAAHSGREEVRPGDIVIAKLDFVFGNDVTMPLAIKKFRELGVNEVFDRERI
AIVLDHFTPNKDIKAAEQCKFSREFAREMGIKWFFEGGNVGVEHCLLPELGLVLPGDLII
GADSHTCTYGALGAFATGVGSTDLAVAMATGEAWFRVPETIKFVYEGDLQPWVTSKDLIL
YTIGDIGVNGALYKVMEFSGEVIQKLSVEQRMTMTNMAIEAGAKTGIIEPDRKTIRYVKD
RAKRRFKLYKSDEDAKYSKVIEYDVSKIEPQVAFPHLPENTVPISKASKMNIKIDQVFIG
SCTNGRLEDLKMAAEVLEGHEVAPWVRLIVIPCSPTVYWKAMKEGILEIFLEAGAVIGPP
TCGPCLGGHMGVLASGERAVSTTNRNFVGRMGHPKSEVYLASPYVAAASAVLGRIASPEE
VVK
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgggaatgacaatagccgaaaagatactcgcggcacactctggaagggaagaagttagg
ccaggagatatagtcattgctaaactcgattttgtcttcgggaatgacgtgacgatgcca
ttagcaataaaaaagtttagagaactcggagtaaatgaggtttttgatagggaaaggata
gccatagtgcttgaccacttcactccaaataaagacataaaagcggctgaacagtgcaag
ttctcaagggagttcgctagagaaatgggaataaagtggttcttcgaaggagggaatgtt
ggtgtcgagcattgtcttctcccagaattaggattagtcctacctggggatctcataatt
ggagctgattcgcatacctgcacctatggagcattaggggcctttgctactggcgtcgga
agcacagacttagcggttgcaatggccactggggaagcttggttcagggttcctgagacg
attaaatttgtgtacgagggggatctccagccatgggtcacctcgaaggacctaatactt
tacaccatcggagacattggagttaatggggctctctataaggtaatggaattctctgga
gaggtcattcaaaagctttcagtggaacagagaatgacaatgacgaatatggcaattgag
gctggagcaaagactggaataatagaacctgatcggaagacaatcagatatgtaaaagac
agggcaaaaaggaggttcaagttatacaagagtgatgaagatgcaaagtattcaaaggta
atagagtatgacgtcagtaaaatagagccacaggtagcgtttcctcacttaccagagaat
accgtgcccataagcaaggcctccaagatgaacataaagatagatcaagttttcatagga
tcttgcacaaatggaaggttagaagatctaaaaatggcagctgaagttctagagggacac
gaagttgctccgtgggtcagattaatagtaattccctgttctccaacggtctattggaag
gctatgaaagagggaatactggagatattcctggaagctggtgccgttattggccctcca
acatgtggtccctgccttggaggacatatgggagttttagcaagtggtgaaagagcagtc
tcaactacaaacagaaattttgttggaagaatggggcatccaaagagtgaagtttacctc
gcgagcccatatgtagctgcagcttcagctgttctgggtaggatagcttctccagaggag
gtggtaaaatga
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