Herpailurus yagouaroundi (jaguarundi): 121009974
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Entry
121009974 CDS
T07555
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu00562
Inositol phosphate metabolism
pyu01100
Metabolic pathways
pyu01521
EGFR tyrosine kinase inhibitor resistance
pyu04012
ErbB signaling pathway
pyu04014
Ras signaling pathway
pyu04020
Calcium signaling pathway
pyu04062
Chemokine signaling pathway
pyu04064
NF-kappa B signaling pathway
pyu04066
HIF-1 signaling pathway
pyu04070
Phosphatidylinositol signaling system
pyu04072
Phospholipase D signaling pathway
pyu04360
Axon guidance
pyu04370
VEGF signaling pathway
pyu04380
Osteoclast differentiation
pyu04611
Platelet activation
pyu04613
Neutrophil extracellular trap formation
pyu04625
C-type lectin receptor signaling pathway
pyu04650
Natural killer cell mediated cytotoxicity
pyu04662
B cell receptor signaling pathway
pyu04664
Fc epsilon RI signaling pathway
pyu04666
Fc gamma R-mediated phagocytosis
pyu04670
Leukocyte transendothelial migration
pyu04722
Neurotrophin signaling pathway
pyu04750
Inflammatory mediator regulation of TRP channels
pyu04919
Thyroid hormone signaling pathway
pyu04933
AGE-RAGE signaling pathway in diabetic complications
pyu04935
Growth hormone synthesis, secretion and action
pyu05167
Kaposi sarcoma-associated herpesvirus infection
pyu05169
Epstein-Barr virus infection
pyu05170
Human immunodeficiency virus 1 infection
pyu05171
Coronavirus disease - COVID-19
pyu05200
Pathways in cancer
pyu05205
Proteoglycans in cancer
pyu05206
MicroRNAs in cancer
pyu05214
Glioma
pyu05223
Non-small cell lung cancer
pyu05225
Hepatocellular carcinoma
Module
pyu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
121009974 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
121009974 (PLCG2)
04014 Ras signaling pathway
121009974 (PLCG2)
04370 VEGF signaling pathway
121009974 (PLCG2)
04064 NF-kappa B signaling pathway
121009974 (PLCG2)
04066 HIF-1 signaling pathway
121009974 (PLCG2)
04020 Calcium signaling pathway
121009974 (PLCG2)
04070 Phosphatidylinositol signaling system
121009974 (PLCG2)
04072 Phospholipase D signaling pathway
121009974 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
121009974 (PLCG2)
04613 Neutrophil extracellular trap formation
121009974 (PLCG2)
04625 C-type lectin receptor signaling pathway
121009974 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
121009974 (PLCG2)
04662 B cell receptor signaling pathway
121009974 (PLCG2)
04664 Fc epsilon RI signaling pathway
121009974 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
121009974 (PLCG2)
04670 Leukocyte transendothelial migration
121009974 (PLCG2)
04062 Chemokine signaling pathway
121009974 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
121009974 (PLCG2)
04919 Thyroid hormone signaling pathway
121009974 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
121009974 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
121009974 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
121009974 (PLCG2)
04380 Osteoclast differentiation
121009974 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121009974 (PLCG2)
05206 MicroRNAs in cancer
121009974 (PLCG2)
05205 Proteoglycans in cancer
121009974 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
121009974 (PLCG2)
05214 Glioma
121009974 (PLCG2)
05223 Non-small cell lung cancer
121009974 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
121009974 (PLCG2)
05171 Coronavirus disease - COVID-19
121009974 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
121009974 (PLCG2)
05169 Epstein-Barr virus infection
121009974 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
121009974 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121009974 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pyu04131
]
121009974 (PLCG2)
Enzymes [BR:
pyu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
121009974 (PLCG2)
Membrane trafficking [BR:
pyu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
121009974 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
121009974 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
SH2_1
PH
SH3_2
Motif
Other DBs
NCBI-GeneID:
121009974
NCBI-ProteinID:
XP_040299351
LinkDB
All DBs
Position
Unknown
AA seq
1152 aa
AA seq
DB search
MGALSVSGKALSAGPEIVGGWSGWEQPVPLPLKPLEVDRAGVSLFCSISLRELKTILPLV
NFKVNSAKFLKDKFVEIGAHKDELSFEQFHLFYKNLMFEQQKSILDEFKKDSSVFILGNT
DRPDASAVYLHDFQRFLLHEQQEVWAQDLNRVRERMTKFIDDTLRETAEPFLFVDEFLTY
LFSRENSIWDEKYDVVDIQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYVRCLRMGC
RCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQ
QRHMARVFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKD
EHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPTELHFGEEWF
HKKVEKRTNAEKLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQHCRIRSVME
GGTMKYFLTDNIMFTSIYDLIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSR
GEAEDMLMRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVLGTSAYFESL
VELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRT
VKALYDYKAKRNDELSFCRGALIHNVSKEPWGWWKGDYGTRIQQYFPSNYVEDISTVDVE
ELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRV
EELFEWFQSIREITWKMDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFR
EIRSFVETKADSVVRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALN
FQTPDKYMQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHL
PKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLR
FVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMQPVLESE
EELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRL
REKRVSNSRFYS
NT seq
3459 nt
NT seq
+upstream
nt +downstream
nt
atgggtgctctcagcgtctctgggaaagccctcagtgcaggccctgaaatagtgggcggg
tggagtggatgggaacagccggtccctctaccgttgaagcccctcgaggtggatagagct
ggggtttccctcttttgcagcatcagcctccgggagctgaagaccatcttgcccctggtc
aacttcaaagtgaacagtgccaagttcctcaaagataagtttgtggaaatcggcgctcac
aaagatgaactcagctttgagcagttccaccttttctataaaaatcttatgtttgagcag
caaaagtcgattcttgatgaattcaaaaaagattcttccgtgttcatcttgggcaacacc
gaccggccggatgcctccgctgtttacctgcacgacttccagcggtttctcctacacgaa
cagcaggaggtttgggctcaggatctgaacagagtccgcgagcggatgacaaagtttatc
gatgacaccctgagggagaccgccgagcctttcttgtttgtcgatgagttcctcacgtac
ctgttttcgcgggagaacagcatctgggacgagaagtacgacgtcgtggacatacaggac
atgaacaaccccttgtcccattactggatctcctcctcacataacacgtacctcaccggc
gaccagctgcggagtgagtcgtccacagaggcatacgtccgctgcctgcgcatgggctgt
cgctgcatcgagctggactgctgggatgggcccgatgggaagcccatcatctaccacggc
tggacgcggaccaccaagatcaagtttgatgacgtcgtgcaggccatcaaagaccatgcc
tttgtcacctcaagcttcccggtgatcctgtccatcgaagagcactgctgtgtggagcag
cagcgccacatggccagggtgttcaaggaggtgtttggcgacctgctgttgacgaagccc
acggaggccagtgctgaccagctgccctcgcccagccagctgcgggagaagatcatcatc
aagcataagaagctgggcccccgaggcgacgtggatgtcaatgtggaagataagaaagat
gagcacaagcaacagggtgaactgtacatgtgggattccattgaccagaaatggacccgg
cactactgtgccatcgctgatgccaagctgtcgttcagcgatgacattgagcagactgca
gaggaggagctgccccaggatataccccccacggagctgcattttggggaggagtggttc
cacaagaaggtggagaagagaacaaatgccgagaagctgctgcaggaatactgtgccgag
acggggggcaaagatgggaccttcttggtgcgggagagcaagaccttccccaacgactac
accctgtccttctggcggtccggccgggtccagcactgccggatccgctccgtcatggag
ggcgggaccatgaagtacttcctgactgacaacatcatgttcaccagcatctatgacctc
atccagcactaccgtgagacgcacctgcgctgtgccgagttcgagctccggctcaccgac
cccgtgcccaaccccaacccccacgagtcaaagccgtggtactatgatggcctgagccgc
ggggaagcagaggacatgctgatgagagttccccgggacggggccttcctgatccggagg
cgggaaggtaccgactcctacgccatcaccttcagggccaggggcaaagtaaagcattgc
cgcatccatcgggacggccggcactttgtgctggggacctctgcctacttcgagagcctc
gtcgagctggtcagttactacgagaagcacgcgctgtaccggaagatgcggctgcgctat
cctgtgacgcctgagctgctggagcgctacaatatggaacgagatatcaactccctctat
gacgtcagcagaatgtatgtggatcccagtgaaatcaacccgtccatgcctcagaggacc
gtcaaagctctgtatgactacaaagccaagcgaaacgatgagctgagcttctgccgtggg
gccctcattcacaacgtctccaaggagccctggggctggtggaaaggagactatggaacc
aggatccagcaatacttcccatccaactacgttgaggacatttcaacggtcgatgtggaa
gaactggaaaagcagattattgaagacaatcccttagggtctctttgcagaggaatactg
gatctcaacacctataacgtcgtgaaagccccgcaggggaaaaaccagaaggcgttcgtg
ttcatcctggagcccaagaagcaaggcgaccctccggtggagtttgccacagacagggtc
gaggagctctttgagtggtttcagagcatccgggagatcacctggaagatggacaccaag
gagaacaacatgaagtactgggagaagaaccagtccatcgccatcgagctctcggacctg
gtagtctactgcaagccgaccagcaagaccaaggacaatttagaaaaccccgacttccga
gaaatccgctccttcgtggagacgaaggctgacagtgtcgtcagacagaaaccggtcgac
ctcctcaagtacaatcagaagggcctgacccgtgtttacccgaagggacagagggtggac
tcctccaactacgacccctttcgcctctggctgtgtggctcccagatggtggcactcaat
ttccagactccagacaagtacatgcagatgaatcaagccttgttctcactcaacgggcgg
acaggctacgtcctgcagcccgagagcatgaggacggagaagtacgaccccatgccgccc
gaatcccagcggaagattctgatgactctgacggtcaaggtcctcggggctcgccatctc
cccaaacttggccgaagcatcgcatgtccctttgtggaggtggaaatctgcggggctgaa
tatgacaacaacaagtttaagaccacagttgtgaatgacaatggcctaagccccgtttgg
gctccgacacaggagaaggtgacctttgaaatttatgacccaaacctcgcgtttctgcgc
tttgtggtctacgaggaagatatgttcagtgatcccaacttcctcgctcatgccacttac
cccatcaaaggaatcaaatcaggattcagatctgttcctctgaagaacgggtacagtgaa
gatatcgagctggcttccctcctggtgttctgtgagatgcagccagtcctggagagtgaa
gaggaactctactcctcctgccgccagctgcgaaggcggcaggaagagctgaacaaccag
ctgttcctgtacgacacacaccagaatctgcgcaatgccaaccgggatgccctcgtgaaa
gagttcaacgtcaacgagaaccagctccaactgtaccaggagaagtgcaaccggaggtta
agagagaagagagttagcaacagtaggttttactcatag
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