| Entry |
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| Symbol |
PLA2G4A
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| Name |
(RefSeq) cytosolic phospholipase A2 isoform X1
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| KO |
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| Organism |
pyu Puma yagouaroundi (jaguarundi)
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| Pathway |
| pyu00592 | alpha-Linolenic acid metabolism |
| pyu04072 | Phospholipase D signaling pathway |
| pyu04270 | Vascular smooth muscle contraction |
| pyu04664 | Fc epsilon RI signaling pathway |
| pyu04666 | Fc gamma R-mediated phagocytosis |
| pyu04750 | Inflammatory mediator regulation of TRP channels |
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| Brite |
KEGG Orthology (KO) [BR:pyu00001]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
121011861 (PLA2G4A)
00565 Ether lipid metabolism
121011861 (PLA2G4A)
00590 Arachidonic acid metabolism
121011861 (PLA2G4A)
00591 Linoleic acid metabolism
121011861 (PLA2G4A)
00592 alpha-Linolenic acid metabolism
121011861 (PLA2G4A)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121011861 (PLA2G4A)
04014 Ras signaling pathway
121011861 (PLA2G4A)
04370 VEGF signaling pathway
121011861 (PLA2G4A)
04072 Phospholipase D signaling pathway
121011861 (PLA2G4A)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
121011861 (PLA2G4A)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
121011861 (PLA2G4A)
04664 Fc epsilon RI signaling pathway
121011861 (PLA2G4A)
04666 Fc gamma R-mediated phagocytosis
121011861 (PLA2G4A)
09152 Endocrine system
04912 GnRH signaling pathway
121011861 (PLA2G4A)
04913 Ovarian steroidogenesis
121011861 (PLA2G4A)
04921 Oxytocin signaling pathway
121011861 (PLA2G4A)
09153 Circulatory system
04270 Vascular smooth muscle contraction
121011861 (PLA2G4A)
09156 Nervous system
04724 Glutamatergic synapse
121011861 (PLA2G4A)
04726 Serotonergic synapse
121011861 (PLA2G4A)
04730 Long-term depression
121011861 (PLA2G4A)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
121011861 (PLA2G4A)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
121011861 (PLA2G4A)
Enzymes [BR:pyu01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
121011861 (PLA2G4A)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
749 aa
MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEVTLMDANYVMDETLGTATFPISSIRVGEKKEV
PFIFNQVTEMFLEMSLEVCSSPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPEKSRG
LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSH
PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYIESLWKKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNSAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEE
LENITAEHIVSNDSSDSDDESQEPKGTENEDAKREYQNDNQASWVHRMLMALVSDSTLFN
TREGRAGKVHNFMLGLNLNTSYPISPLKDFTTQESLDEDELDTAVADPDEFEQIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMN
KLPFPKIDPNVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRNYKAPGVPRETK
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIVESIEYRR
QNPSRCSVSLSNVEARRFFNKEFLSKPAA |
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| NT seq |
2250 nt +upstreamnt +downstreamnt
atgtcatttatagatccttatcagcacattatagtggagcaccagtattcccacaagttc
acagtagtggtgttacgtgccaccaaagtgacaaagggggccttcggtgacatgcttgat
accccagatccctatgtggaacttttcatctcctcaacccctgacagcaggaagagaaca
agacacttcaataatgacataaacccagtgtggaatgagacctttgaatttattttggat
cctaatcaggaaaatgttttggaggtcacattaatggatgccaattatgtcatggatgaa
actctaggaacagcaacattccccatatcctctatcagagtgggagagaagaaagaagtt
ccttttattttcaaccaagtcactgaaatgtttctggaaatgtctcttgaagtttgttca
tccccagacctccgattcagtatggctctgtgtgatcaggagaagactttcagacaacag
aggaaagaaaacataaaggaaaacatgaagaaactcctgggtccagagaagagtagaggc
ctgtattctacgcgcgatgtgcctgtggtggccatactgggctcaggtggagggttccga
gccatggtcggattctccggtgtgatgaaggcactatatgaatcaggaattttggactgt
gctacttacgttgctggcctttctggctccacatggtacatgtcaaccttatattctcac
cccgattttccagagaaagggccagaggagattaatgaagagctaatgaaaaatgttagc
cacaacccccttttacttctcacaccacagaaagttaagagatacattgagtctctatgg
aagaagaaaagctctgggcaacctgtcacctttactgacatctttgggatgttaattgga
gaaacactaattcacaatagaatgaacactaccttgagtagtttgaaggaaaaagtcaat
tctgcacaatgccctttaccccttttcacctgtctccatgtcaaacctgatgtttcggag
ctgatgtttgcagattgggttgaatttagtccatatgagattggcatggctaaatatggt
acttttatggctcctgacttatttggaagcaaattttttatgggaacagttgtgaagaaa
tatgaagaaaaccccttgcatttcttaatgggtgtctggggcagtgcgttttctatattg
ttcaacagagtcttgggagtttctggctcacaaaataaaggttccacaatggaggaagaa
ctagaaaatattacagcagagcatattgtgagtaatgacagctcggatagcgatgatgaa
tcacaagaacccaaaggcactgaaaatgaagatgctaaaagggaatatcaaaatgataac
caagcaagttgggtccatcgtatgttaatggctttggtgagtgattcaactttattcaat
accagagaaggacgtgctgggaaggtacacaacttcatgttgggcttgaatctcaataca
tcctatccaatatctcctctgaaagactttaccacacaggaatcgttggatgaagatgaa
ttggatacagctgttgcagatcctgatgaatttgagcaaatatatgagcctctggatgtc
aaaagtaaaaagattcatgtagtggacagtggcctcacatttaacctgccataccccttg
atcctgagacctcagagaggagtcgatctcattatctcctttgacttttctgcacgacca
agtgactctagtcctccattcaaggaacttctacttgcagaaaagtgggccagaatgaac
aagcttccatttccaaagattgatcccaatgtgtttgatcgagaaggactgaaggaatgc
tatgtctttaaacccaagaatcctgacgttgagaaagattgcccaactatcatccacttt
gttctggccaacatcaacttcagaaattacaaggcaccaggtgtcccaagagaaactaag
gaagagaaagaaatagctgattttgatatttttgatgaccccgaatcaccattttcaacc
ttcaactttcaatatccaaatcaagcattcaaaaggctgcatgatctcatgtacttcaat
accctgaacaacattgatgtgataaagaacgccatagttgaaagcattgaatacagaaga
cagaatccgtctcgttgctcggtttctcttagtaatgttgaagcaagacgattcttcaac
aaggaatttctaagcaaacctgcagcatag |
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