KEGG   Puma yagouaroundi (jaguarundi): 121012223
Entry
121012223         CDS       T07555                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
pyu  Puma yagouaroundi (jaguarundi)
Pathway
pyu01521  EGFR tyrosine kinase inhibitor resistance
pyu01522  Endocrine resistance
pyu04012  ErbB signaling pathway
pyu04015  Rap1 signaling pathway
pyu04062  Chemokine signaling pathway
pyu04081  Hormone signaling
pyu04137  Mitophagy - animal
pyu04144  Endocytosis
pyu04360  Axon guidance
pyu04370  VEGF signaling pathway
pyu04510  Focal adhesion
pyu04520  Adherens junction
pyu04530  Tight junction
pyu04540  Gap junction
pyu04611  Platelet activation
pyu04613  Neutrophil extracellular trap formation
pyu04625  C-type lectin receptor signaling pathway
pyu04727  GABAergic synapse
pyu04750  Inflammatory mediator regulation of TRP channels
pyu04810  Regulation of actin cytoskeleton
pyu04912  GnRH signaling pathway
pyu04915  Estrogen signaling pathway
pyu04917  Prolactin signaling pathway
pyu04919  Thyroid hormone signaling pathway
pyu04921  Oxytocin signaling pathway
pyu04926  Relaxin signaling pathway
pyu05100  Bacterial invasion of epithelial cells
pyu05135  Yersinia infection
pyu05152  Tuberculosis
pyu05161  Hepatitis B
pyu05163  Human cytomegalovirus infection
pyu05167  Kaposi sarcoma-associated herpesvirus infection
pyu05168  Herpes simplex virus 1 infection
pyu05203  Viral carcinogenesis
pyu05205  Proteoglycans in cancer
pyu05207  Chemical carcinogenesis - receptor activation
pyu05208  Chemical carcinogenesis - reactive oxygen species
pyu05219  Bladder cancer
pyu05417  Lipid and atherosclerosis
pyu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    121012223 (SRC)
   04015 Rap1 signaling pathway
    121012223 (SRC)
   04370 VEGF signaling pathway
    121012223 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    121012223 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    121012223 (SRC)
   04137 Mitophagy - animal
    121012223 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121012223 (SRC)
   04520 Adherens junction
    121012223 (SRC)
   04530 Tight junction
    121012223 (SRC)
   04540 Gap junction
    121012223 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    121012223 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121012223 (SRC)
   04613 Neutrophil extracellular trap formation
    121012223 (SRC)
   04625 C-type lectin receptor signaling pathway
    121012223 (SRC)
   04062 Chemokine signaling pathway
    121012223 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    121012223 (SRC)
   04915 Estrogen signaling pathway
    121012223 (SRC)
   04917 Prolactin signaling pathway
    121012223 (SRC)
   04921 Oxytocin signaling pathway
    121012223 (SRC)
   04926 Relaxin signaling pathway
    121012223 (SRC)
   04919 Thyroid hormone signaling pathway
    121012223 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    121012223 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    121012223 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    121012223 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    121012223 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    121012223 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    121012223 (SRC)
   05203 Viral carcinogenesis
    121012223 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    121012223 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    121012223 (SRC)
   05168 Herpes simplex virus 1 infection
    121012223 (SRC)
   05163 Human cytomegalovirus infection
    121012223 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121012223 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    121012223 (SRC)
   05152 Tuberculosis
    121012223 (SRC)
   05100 Bacterial invasion of epithelial cells
    121012223 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121012223 (SRC)
   05418 Fluid shear stress and atherosclerosis
    121012223 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121012223 (SRC)
   01522 Endocrine resistance
    121012223 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pyu01001]
    121012223 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pyu04131]
    121012223 (SRC)
Enzymes [BR:pyu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     121012223 (SRC)
Protein kinases [BR:pyu01001]
 Non-receptor tyrosine kinases
  SRC family
   121012223 (SRC)
Membrane trafficking [BR:pyu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    121012223 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    121012223 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    121012223 (SRC)
  Macropinocytosis
   Kinases
    121012223 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 121012223
NCBI-ProteinID: XP_040303031
LinkDB
Position
Unknown
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagcct
gctgagaacacccacggtggtggtgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccccagtacggccttcccctctgccgctgctgag
cccaagctgttcgggggcttcaactcctcggacacagtcacctccccgcagagggcgggg
ccgctggcgggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
actgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaggtg
gacgtcagccagacctggttcacattcagatggctgcaaagagagggtgactggtggctg
gcccactcactcagcacaggacagacgggctacatccccagcaactatgtggcaccctct
gactctatccaggccgaagagtggtactttggcaagatcaccagacgggagtcagagagg
ttactgctcaatgcggaaaacccaagagggaccttcctagtgcgagaaagcgagaccacg
aaaggcgcctactgcctctccgtgtccgatttcgacaacgccaagggcctcaatgtgaag
cattacaagatccgcaagctggacagcggtggcttctacatcacctcccgcacccagttc
aacagtctgcagcagctggtggcctactactccaaacatgccgacggcctctgccaccgc
ctcaccaccgtgtgccccacgtccaagccacagactcagggcctggccaaagacgcctgg
gagatcccccgggagtccctgcggctggaggtcaagctgggccagggctgtttcggagag
gtgtggatgggaacctggaacggaaccaccagggtggccatcaaaaccctgaagccaggc
acaatgtctccagaggcctttctgcaggaggcccaggtcatgaagaaactaaggcacgag
aaattggtgcagctgtatgccgtggtgtctgaggagcccatctacattgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggagacaggcaagtacctgcggctg
ccacagctggtggacatggctgctcagatcgcctcgggcatggcctacgtggagcggatg
aactacgtgcaccgggacctccgtgctgccaacattctggttggagagaacctcgtgtgc
aaagtggccgacttcgggctggctcggctcatcgaagacaatgaatacaccgcccggcaa
ggtgccaaattccccatcaagtggacggctccagaagcggccctgtacggccggttcacc
atcaagtcagatgtgtggtcctttgggatcctgctgacggagctcacaacaaagggacgg
gtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccgcctgagtgtcccgagtccctgcatgacctcatgtgccagtgctggcgg
aaggaaccggaagagcggcccaccttcgagtacctgcaggccttcctagaggactacttc
acgtccaccgagccccagtaccagcctggagagaacctatag

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