Puma yagouaroundi (jaguarundi): 121013973
Help
Entry
121013973 CDS
T07555
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu04217
Necroptosis
pyu04380
Osteoclast differentiation
pyu04620
Toll-like receptor signaling pathway
pyu04621
NOD-like receptor signaling pathway
pyu04630
JAK-STAT signaling pathway
pyu04658
Th1 and Th2 cell differentiation
pyu04659
Th17 cell differentiation
pyu05145
Toxoplasmosis
pyu05160
Hepatitis C
pyu05161
Hepatitis B
pyu05162
Measles
pyu05164
Influenza A
pyu05165
Human papillomavirus infection
pyu05167
Kaposi sarcoma-associated herpesvirus infection
pyu05168
Herpes simplex virus 1 infection
pyu05169
Epstein-Barr virus infection
pyu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
121013973 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
121013973 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
121013973 (TYK2)
04621 NOD-like receptor signaling pathway
121013973 (TYK2)
04658 Th1 and Th2 cell differentiation
121013973 (TYK2)
04659 Th17 cell differentiation
121013973 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
121013973 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
121013973 (TYK2)
05160 Hepatitis C
121013973 (TYK2)
05171 Coronavirus disease - COVID-19
121013973 (TYK2)
05164 Influenza A
121013973 (TYK2)
05162 Measles
121013973 (TYK2)
05168 Herpes simplex virus 1 infection
121013973 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
121013973 (TYK2)
05169 Epstein-Barr virus infection
121013973 (TYK2)
05165 Human papillomavirus infection
121013973 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
121013973 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121013973 (TYK2)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
121013973 (TYK2)
Protein kinases [BR:
pyu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
121013973 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
RIO1
ABC1
RA_2
Motif
Other DBs
NCBI-GeneID:
121013973
NCBI-ProteinID:
XP_040305794
LinkDB
All DBs
Position
Unknown
AA seq
1181 aa
AA seq
DB search
MPLCRWGATTRDSRPDGDEAQPMVSRGVLKVLLHWAGPDGGDPWVTFSEATLTAEEVCIH
IAHKVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDMNLTLYFRMRFYFRNWHSMNPQE
PAVYRCGPTRAKSSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVAPLWELSSEEEIHHF
KNESLGMAFLHLCHLALCHGIPLEKVAKKISFKDCIPRSFRLQLRRHNALTRLRLRRLFR
RFVRAFQPGHVSQPVIMVKYLATLEQLAPRFGTERVLVCRLEEQARAVGDPCYVRDGSQS
PPEPGPELAPGPPTHEVLVTGTGGIRWRPVQAEGPSGDGCSRNPRAGPSGKKSKAQEVGN
QPVDRPQEAPWAYFCDFQDITHVVLKERHVSIHRQDKCLELTLPSRAVALSLVSLVDGYF
RLTADSSHYLCREVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSHLNRLI
LTVAQRDQAPGGQQLHLRKFPIELRAGSFELEGWDRSFPSVRELRTALQGCSLRAGDDCF
SLRRCCLPRPGELSNLIIMRGSRASPGPLNLSQLSFHRVCQDDITQLSHLGQGTRTNVYE
GILRVGERGPKEGTADGGDPPTPSGDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS
HVHLAFVHGVCVHGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVAVAQQLASALSYLE
DKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAPECLSG
GASTLTTAADKWGFGVTLLEICFDGEAPLQGRGPSEKECFYQKQHQLPQPSCPELATLTS
QCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFHKRYLKKIRDLGEG
HFGKVSLYCYDPTNDGTGEMVAVKALKAGGGPQLRTGWRREIDILRTLYHKHIVKYKGCC
EDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFAQQICEGMAYLHAQHYVHRDLAA
RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWS
FGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPEKCPCEIYL
LLKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFNVC
NT seq
3546 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccgttggggtgccaccaccagggacagcaggcctgatggggatgaggct
cagcccatggtctccaggggagtcctaaaggtcctcctgcactgggctggccctgatggc
ggggacccctgggtcaccttcagcgaggccacactgaccgcagaggaggtctgcatccac
atcgcacacaaagtcggcatcactccatcctgcctcaatctcttcgccctctttgatgcc
caggcccaggtgtggctgcccccaaaccacatcttggaggtctccagagacatgaacctg
acattgtacttccgcatgaggttttatttccggaactggcacagcatgaatcctcaggag
ccggccgtgtaccgctgtgggcccaccagggccaagtcttcctcggaacaggcagagcag
ggggtgcaactcctggacccagcctcctttgagtacctctttgagcagggcaagcacgag
tttgtgaatgatgtggcaccactgtgggagctgtcgagcgaggaggagatccaccatttt
aagaacgagagcctgggcatggcctttctgcacctctgccacctcgccctttgccatggt
atccccctggagaaggtggccaagaagatcagcttcaaggactgcatcccgcgctccttc
cggctgcagctccggcggcacaacgcgttaacacggctgcgcctacggaggctcttccgc
aggtttgtgcgggccttccagccgggccacgtctcccagccggtcatcatggtcaagtac
ctggccacgctggagcagctggcaccccgcttcggcacggagcgcgtgctcgtgtgccgg
ctggaggagcaggcccgggccgtgggggacccctgctacgtccgggacgggagccagtcc
cccccggagcctgggcctgaattggcccccggaccccctactcatgaggtgctggtgaca
ggcactggtggcatccggtggcggccagtccaggcagagggtcccagtggcgatggttgc
agcaggaacccccgtgctggcccatcagggaagaaaagcaaggcccaggaggtgggcaac
cagccagtggacaggcctcaggaagcgccatgggcctacttctgtgacttccaggacatc
acccacgtggtgctgaaagagcgccacgtcagcatccaccgtcaggacaagtgcctggag
ctcaccctgccttcccgggctgtggccctgtccttggtgtcgctggtggacggctatttc
cgcctgacggccgactcgagccactacctgtgccgggaggtggcccctccacggctggtg
atgagcatccgggatggcatccacgggcccttgctggagccattcgtgctggccaagctg
cggcctgaagatggcctctacctcatccactggagcaccagccacctcaaccgtctcatc
ctcacggtggcccagcgtgaccaggcacctggcgggcagcagctgcacctccgtaaattc
cccattgagctgcgggccgggagcttcgagctggagggctgggaccgctccttcccgagc
gtgcgggagctgcgcactgccctgcagggctgctcgctgcgggccggggacgactgtttc
tccctgcgccgctgctgcctgccacggcccggagagctctccaacctcatcatcatgcgt
gggtctcgggccagccctgggccactcaacctcagccagctcagcttccaccgcgtctgc
caggatgacattacccagctgtctcacttgggccaaggcacgaggaccaatgtgtatgag
ggcatcttacgggtgggggaaagaggtcccaaggagggcacggcagatggtggggacccc
cccacgcccagtggggaccgtgggcaggagctacgagtggtactcaaggtgctggatccc
agtcaccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtctcc
cacgtgcacctggcctttgtgcacggcgtctgcgtgcacggctctgagaacatcatggtg
acggagtacgtggagcacggacccctggatgtgtggctgcggcgggagaggggccacgtg
cctgtggcctggaaggtggcagtggcccagcagctggccagcgctctcagctacctggaa
gacaagagcctggttcatggtaacgtgtgtggccggaacatcctgctggcacggctggga
ctggcggagggcaccagccccttcatcaagctgagcgatcccggtgtgggcctgggcgcc
ctttccagggaggagcgggtagagaggatcccctggacagcccccgagtgcctgtcaggt
ggggccagcaccctaaccactgcagctgacaaatggggctttggtgtcaccctcctggag
atctgcttcgacggggaggcccctctgcagggccgcggcccttctgagaaagagtgcttc
taccagaagcagcaccagcttcctcagccctcatgcccggagctggccacactcaccagc
cagtgcctgacctatgaaccagctcagcggccctccttccgcaccatcctgcgtgacctc
actcagctgcagccccagaatcttgctgacgtcttggctgtgaaccccgactcgcctgca
tcagaccccaccgttttccacaagcgctatttgaaaaagatccgggatctgggcgagggt
catttcggcaaggtcagtctgtattgctacgacccgactaacgacggcaccggcgagatg
gtggctgtgaaggccctcaaggcaggtgggggcccccagctccgcactggctggcggcgg
gagatcgacatcctgcgcacgctctaccacaagcacatcgtcaaatacaagggatgctgt
gaggaccaaggagagaagtcggtgcagctcgttatggagtacgtgcctctgggcagcctc
cgggactaccttccccggcacaacgtcggactggcccaactgctactcttcgcccagcag
atctgtgagggcatggcctaccttcatgcacagcactacgtccaccgagacctggctgcc
cgcaacgtgctgctggacaacgacaggctggtcaaaatcggggactttggcctagccaag
gctgtgcctgaaggccatgagtactaccgcgtgcgcgaagatggggacagccccgtattc
tggtatgctccagagtgcctgaaggagtgtaagttctactatgcatccgacgtctggtcc
ttcggggtcaccatgtatgagctgctgacctactgtgactccagccagagccccccttcg
aaattcatcgagctcataggcctcacccaagggcagatgacggtgctgaggctcactgag
cttctggaacgaggggagaggctgccgcggccagagaaatgcccttgcgagatctacctc
ctcctgaagaactgctgggaggcagaggcctcattccgccccactttccagaacctcatc
cccattctcaagacggtccaggagaaataccaaggccaggccgcctcagtgttcaatgtg
tgctga
DBGET
integrated database retrieval system
