Herpailurus yagouaroundi (jaguarundi): 121015275
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Entry
121015275 CDS
T07555
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu04140
Autophagy - animal
pyu04141
Protein processing in endoplasmic reticulum
pyu04210
Apoptosis
pyu04932
Non-alcoholic fatty liver disease
pyu05010
Alzheimer disease
pyu05012
Parkinson disease
pyu05014
Amyotrophic lateral sclerosis
pyu05016
Huntington disease
pyu05017
Spinocerebellar ataxia
pyu05022
Pathways of neurodegeneration - multiple diseases
pyu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
121015275 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
121015275 (ERN1)
09143 Cell growth and death
04210 Apoptosis
121015275 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
121015275 (ERN1)
05012 Parkinson disease
121015275 (ERN1)
05014 Amyotrophic lateral sclerosis
121015275 (ERN1)
05016 Huntington disease
121015275 (ERN1)
05017 Spinocerebellar ataxia
121015275 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
121015275 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
121015275 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
121015275 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121015275 (ERN1)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
121015275 (ERN1)
Protein kinases [BR:
pyu01001
]
Serine/threonine kinases: Other
IRE family
121015275 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
121015275
NCBI-ProteinID:
XP_040308038
LinkDB
All DBs
Position
Unknown
AA seq
973 aa
AA seq
DB search
MCLGCGLSNLSIFIFEIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLLEDDGDYKISHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEV
EEKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKE
LEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSAS
RAGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQAN
ILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDGPIVKQLERGGKAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLFQPYYFHE
PPELRPPVTPDAL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgtgccttggatgcgggctctctaacctcagcatcttcatctttgagatttttggaagt
cccagcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttg
catgctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctg
caggttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctg
tatacacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatcccagag
ctcgtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtatgttattgatcttctgaccggggagaagcagcagactttgtcatcagcc
tttgcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtacaca
atcaccatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactac
gcggcctcactgctggaggacgacggggactacaagatatcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactac
gcttcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcac
atcaacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgtcgggaaatactctaccagcctgtatgcctccccctccatggtgcacgag
ggggtcgccgttgtgccccggggcagcacacttcctttgctggaaggcccccagactgac
ggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagttt
gaccctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataat
ctgcccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggtcgagcagacttcagaaaacgcgcccaccgccgtttcacaggaggtg
gaggagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctgtgctgaag
gacatagctaccatcatcctgagcaccttcctgctcattggctgggtggccttcatcatc
acctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccaaaaggaa
ctagagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggagacgtg
gctcaggatgctgagctcctggactcgtccggcctgtactcagagagctcgggcaccagc
agccccagcacgtcccccagagcctccaaccactcgctccactccagtggctctgcctcc
agggctggtgccagccccttcctggagcaggacgatgaagatgaggaaaccagcatggtg
attgttgggaagatctcattctgtcccaaggacgtgctgggccacggagctgagggcacg
attgtgtaccggggcatgttcgacaaccgcgacgtggccgtcaagaggatcctccccgag
tgtttcagtttcgcggaccgtgaggtccagctgcttcgggaatcagacgagcaccccaac
gtgattcgttacttctgcacggagagggatcggcagttccagtacattgccatcgagctg
tgtgcggccaccctgcaggagtacgtggaacagaaggacttcgcccacctcggcctggag
cccatcaccttgctgcagcagaccacctcgggcctggcccatttgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctgtccatgcccaatgcacatggcagg
atcaaggccatgatctctgacttcggcctctgcaagaagctggctgtgggcaggcacagt
ttcagccgccgctcaggagtgcctggcacagaaggctggatcgctccggagatgctgagc
gaggactgtaaggacaatcctacctacacagtggacatcttctctgcgggctgtgtcttt
tactacgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaac
atcctcctgggcgcctacagcctcgactgcttacacccggagaagcacgaagacgtcatt
gcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccctctgcgaag
catgtgctgaagcacccgttcttctggagcctggaaaagcagctccagttcttccaggac
gtgagtgaccgaatagaaaaggaatccctggacggcccgatagtgaagcagctggagcga
ggcgggaaagccgtggtgaagacggactggagagagaacatcaccgtccccctgcagaca
gatctgcgtaaattcagaacctataaaggtggctctgtccgcgaccttctccgagccatg
agaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctct
ctccccgacgactttgtgcgctacttcacgtcccgcttcccccacctcctcccccacacc
taccgggccatggagccctgcagccacgagaggctcttccagccttactacttccacgag
cccccagagctccggccccctgtgactccagacgccctttga
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