Puma yagouaroundi (jaguarundi): 121019674 Help Entry 121019674         CDS       T07555                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu04072   Phospholipase D signaling pathway pyu04115   p53 signaling pathway pyu04140   Autophagy - animal pyu04150   mTOR signaling pathway pyu04151   PI3K-Akt signaling pathway pyu04152   AMPK signaling pathway pyu04211   Longevity regulating pathway pyu04218   Cellular senescence pyu04714   Thermogenesis pyu04910   Insulin signaling pathway pyu04919   Thyroid hormone signaling pathway pyu05163   Human cytomegalovirus infection pyu05165   Human papillomavirus infection pyu05168   Herpes simplex virus 1 infection pyu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pyu00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     121019674 (TSC2)    04151 PI3K-Akt signaling pathway     121019674 (TSC2)    04152 AMPK signaling pathway     121019674 (TSC2)    04150 mTOR signaling pathway     121019674 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     121019674 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     121019674 (TSC2)    04218 Cellular senescence     121019674 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     121019674 (TSC2)    04919 Thyroid hormone signaling pathway     121019674 (TSC2)   09149 Aging    04211 Longevity regulating pathway     121019674 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     121019674 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     121019674 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     121019674 (TSC2)    05163 Human cytomegalovirus infection     121019674 (TSC2)    05165 Human papillomavirus infection     121019674 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:pyu01009]     121019674 (TSC2) Protein phosphatases and associated proteins [BR:pyu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      121019674 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Motif Other DBs NCBI-GeneID:  121019674 NCBI-ProteinID:  XP_040315297 LinkDB All DBs Position Unknown AA seq 1809 aa AA seqDB search MAKPTSKDSGLKEKFRILFGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVKDMLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSVTRLIKKYRRELQAVTWDI LLDIIERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSHERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHIPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVMARSLS APPELEERDVVAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVYETLVSHLQLHYKH GYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDSTEPERGSEKKAG GPLSPPTGPSGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLGKLPESLRFK VLIFTSPCSVDQLSSALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKARQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVREFQESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSAELQGSPELSSDPSAHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG ALDAPATHCPGSQTTPASTSERASAAAQLPAQEKTSLAAYVPLLTQGWAEILVRRPTGNT SWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKPPPP PRSNTVASFSSLYQTSCQGELHRSISWADSAVVLEEGSPSETDLPGEPTELEDFEATLGP ERRCRRPEAYSRSSSSSSQEEKSFAAEEVAAGGLPIGRAVSAEGARPSAGLSFQPAQPLS KSSSSPELQTLQDTLGDPGDKADVGRLSPEAKARSQSGTLDGAGATWSTPGEESQGRGPV RPEGPLPSGCPRSPGGLRPRGYTISDSAPSRRGKRVERDAFKSRAGASNTEKVPGINPSF VFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAI LSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHI ATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECN LVSLQCRKDMEGLVDTSVAKIVSDRNLSFVARQMALHANMASQVHHSRSNPTDIYPSKWI ARLRHIKRLRHRVGQIREEAHYSNPSLPLTQTHPPGHAKAPAPAEPMPTYETGQRKRLIS SVDDFTEFV NT seq 5430 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgacaagcaaggattcaggcttgaaggagaagttcaggattctgtttgga ctgggaaccccgcggccaaaccccaggtctgcagagggcaagcagacggagtttatcatc acggcggaaatcctgagagagctgagcgttgaatgtggcctcaacaatcgcatccgggtg atagggcagatctgtgaagttgcaaaaacgaagaagtttgaagagcatgcagtggaagcg ctctggaaggccgtcaaggacatgctgcagccagagcggccaccggaggcccggcatgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcttgggcgttctcagg gccctcttctttaaggtcatcaaggattacccctctaatgaagatctccatgaaagactg gaagttttcaaggccctcacagacaatgggagacacatcacatatttggaagaagaactg gctgggtttgtgctgcagtggatggacatcggcctgtcctcagagttccttctggtgctt gtgaacttggtcaaattcaacagctgttacctggatgaatacatcgcatcaatggtccac atgatctgcctgctgtgcgtccagactgtgtcctccgtggacatagaggtctctctgcag gtgctggacgccgtcgtctgctacaactgcctgccggctgagagcctgcccctgttcatc gtcactctctgtcgtaccgtcaacgtcaaggagctctgtgagccttgttggaagctgatg cgtaatcttctgggcacccacctgggtcacagtgccatctacaacatgtgccgcatcatg gaggacagagcctacatggaagatgccccgctgctgagaggggccgtgttctttgtgggc atggctctctggggggcgcaccgactctactcgctcaagaactccccaacatccgtgctg ccgtcgttttacgaggccatgacctgtccgaacgaggtggtgtcctatgaaatcgtcctg tctgtcaccagactcatcaagaagtaccggagggagctccaggctgtgacgtgggatatc ctgctggacatcatcgaacgtctgctgcaacagctccagagcctggacagcccggagctc agagccatcgtccatgacctgctgaccacagtggaggagctgtgtgaccagaatgagttc cacggctcgcatgagagatacttcgagctcgtcgagagatgtgcagaccagaggccggag tcctccctcctaaacttaataacctacagggctcagtccatccatccggcaaaggacggc tggattcacaacctgcagttactgatggagagattcttccggaatgaatcccgcagtgct gtgcgcatcaaggtgctcgacgtcctgtcctttgtgctgctcatcaacaggcagttctat gaggaggagctgatcagctcggtggtcatctctcagctctcccacatcccggaggacaaa gacccccaagtccggaaactggccacccagttgctggtggacctggccgaaggctgtcac acccaccacttcaacagcctgctagacattgtggagaaggtgatggcccgctccctttcc gcaccccctgagctggaggaaagagatgtggtggcatattcagcctccttagaggatgtg aagactgccgtcttggggctcctggtgatccttcagaccaagctgtacgccttgcctgcc agccacgcggtgcgtgtgtacgagaccctcgtcagccacctgcagctccactacaagcac ggctataccctgcccatcgccagtagcatccggctgcaggcctttgacttcctgctgctg ctgagggcggactccctgcaccgcctcggcctgcccagcaaggacggggctgtgaggttc agcccctactgcgtctgcgactccacggagccagagagaggctctgagaagaaggccggc ggccccctgtcgcctcccaccgggccgtccggcccagcacctgccggtcctgctgtgcgg cttggctccctgccctactccctgctcttccgggtcctgctgcagtgcttgaagcaggag acggactggaaggtgctgaagcttgttctcggcaagctgcccgagtccctgcgcttcaag gtcctcatcttcacgtccccgtgcagcgtcgaccagctgtcttccgccctctgctccatg ctttcaggtcccagaactctggagcggctccgaggcaccccggaaggtttctccaggacc gacctgcacctggctgtggttcctgtgctgacggcgttaatctcttaccataactatttg gacaaagccagacagcgggagatggtgtactgcctggagcaaggcctgatctaccgctgt gccagccagtgcgtggtggccctggccgtgtgcagcgtcgaaatgcccgacatcatcatc aaggcgctgcctgtcttggtcgtgaagctcacacacatttcggccacagccagcatggcc attccactcctcgaattcctgtcaactctggccaggctgcctcacctctacaggaacttt gccgctgagcagtacgcgagtgtgtttgccatctccctgccgtacaccaacccctccaag tttaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcattagatgc cgtctgccttttcggaaggattttgttccttatatcactaagggcctacgctccaatgtc ctcctgtcttttgacgacaccccggagaaggacagcttcagagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactcc ccacccgtgagagaattccaggagagctctgcagccgacgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcacgagtgccagcttg gggtctgcggatgagaactcaatggcccaggctgacgacaacttgaaaaatctccacctg gagctcacggagacttgtctggacatgatggccagatacgtgttctccaacttcacggcg gtccccaagaggtcccctgtaggggagttcctcttggctggcggcaggaccaagacctgg ctggttggaaacaagctcgtcactgtgacgacgagcgtggggaccggaacccggtcactg ctgggcttggactcagcagagctgcagggcagcccagagctgagctctgaccccagtgcg cacgtgaggcagacaaaggaggcgcctgccaagttggagtcccaggctgggcagcaggtg tgccgtggggcccgggaccgcgtccgctccatgtctgggggccacggccttcgtgttggt gccttggacgctccagccacccattgcccaggctcacagaccacaccagccagcacgtcc gagagggcctcggctgccgcccagctcccggcacaggagaagacgagcctggcggcctac gtacccctgctgacccagggctgggcggagatcttggtccggaggcccacggggaacacc agctggctgatgagcctggagaaccccctcagccccttctcctcggacatcaacaacatg cccctgcaggagctgtccaacgccctcatggccgctgagcgcttcaaggagcgtcgtgac acggccctgtacaagtcactttcggtgccggcggccggctccgccaagccccctccgccc ccacgctctaacacagtggcctctttctcctccctgtaccagaccagttgccaaggagag ctgcacaggagcatttcctgggcagactccgcggtggttctggaggagggaagtcccagc gagactgatttgccgggcgagcccactgagctggaggactttgaggccaccctgggccca gagaggcgctgtcggcgccccgaagcctacagtagatcgtcttccagctccagccaagag gagaagtctttcgccgcagaggaggtggctgccggagggctccccatcgggcgggccgtg tctgccgagggagcccgaccctctgcggggctctccttccagcccgcccagcccctcagc aagtctagctcctcgccggagctgcagaccctgcaggatacactcggggaccctggggac aaggccgacgttggccggctgagccccgaggccaaggcccgctcacagtccgggactctg gatggggcaggtgccacctggtcaaccccaggtgaagagagtcagggccggggccctgtg aggcccgagggtcccttgccttctggctgtccccgttcccccggtggcctgcgtcccaga ggctacaccatttcggattcagccccgtcacgcagaggcaagagggtagagcgggacgcc ttcaagagcagagctggggcctccaatactgagaaggtgccgggcatcaaccccagcttc gtgttcctgcagctctaccactctcctttctttggcgacgagtccaacaagccgatcctt ctgcctaacgagtccttcgagcggtcggtgcagctcctcgaccagatcccatcctacgac acgcacaagatcgcggtcctgtacgtgggagaaggccagagcagcagcgaactcgccatc ctgtccaacgagcacggctcgtaccggtacacagagttcctgacgggcctgggcaagctc atcgagctcaaggactgccagccggataaggtgtacctgggcggtctggacgtgtgcggg gaggacggccagttcacctactgctggcacgatgacatcatgcaggctgtcttccatatc gccaccctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgccatctg ggcaacgactttgtgtccattgtctataatgactccggcgaggacttcaaactgggcacc attaaaggccagttcaacttcgtccacgtgatcatcacccccctggactacgagtgcaac ctggtgtcgctgcagtgcaggaaggacatggagggcctcgtggacaccagcgtggccaag atcgtgtctgatcgcaacctgtccttcgtggcccgtcagatggctctgcatgccaacatg gcctcccaggtgcaccatagccgctccaaccccacggatatctacccgtccaagtggatc gccaggctccgtcacatcaagcggctgcgccaccgggtagggcagatccgtgaggaagcc cactactccaaccccagcctgccgctgacgcagacgcaccctccgggccacgccaaggcc ccagccccggccgagcccatgcccacgtacgagacgggccagcggaagcgcctcatctcc tctgtggatgacttcaccgagttcgtgtga

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