KEGG   Herpailurus yagouaroundi (jaguarundi): 121021720
Entry
121021720         CDS       T07555                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
pyu  Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu04010  MAPK signaling pathway
pyu04020  Calcium signaling pathway
pyu04022  cGMP-PKG signaling pathway
pyu04024  cAMP signaling pathway
pyu04260  Cardiac muscle contraction
pyu04261  Adrenergic signaling in cardiomyocytes
pyu04270  Vascular smooth muscle contraction
pyu04723  Retrograde endocannabinoid signaling
pyu04725  Cholinergic synapse
pyu04726  Serotonergic synapse
pyu04727  GABAergic synapse
pyu04911  Insulin secretion
pyu04912  GnRH signaling pathway
pyu04921  Oxytocin signaling pathway
pyu04924  Renin secretion
pyu04925  Aldosterone synthesis and secretion
pyu04927  Cortisol synthesis and secretion
pyu04929  GnRH secretion
pyu04934  Cushing syndrome
pyu04935  Growth hormone synthesis, secretion and action
pyu05010  Alzheimer disease
pyu05020  Prion disease
pyu05022  Pathways of neurodegeneration - multiple diseases
pyu05207  Chemical carcinogenesis - receptor activation
pyu05410  Hypertrophic cardiomyopathy
pyu05412  Arrhythmogenic right ventricular cardiomyopathy
pyu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121021720 (CACNA1S)
   04020 Calcium signaling pathway
    121021720 (CACNA1S)
   04024 cAMP signaling pathway
    121021720 (CACNA1S)
   04022 cGMP-PKG signaling pathway
    121021720 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    121021720 (CACNA1S)
   04929 GnRH secretion
    121021720 (CACNA1S)
   04912 GnRH signaling pathway
    121021720 (CACNA1S)
   04921 Oxytocin signaling pathway
    121021720 (CACNA1S)
   04935 Growth hormone synthesis, secretion and action
    121021720 (CACNA1S)
   04924 Renin secretion
    121021720 (CACNA1S)
   04925 Aldosterone synthesis and secretion
    121021720 (CACNA1S)
   04927 Cortisol synthesis and secretion
    121021720 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    121021720 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    121021720 (CACNA1S)
   04270 Vascular smooth muscle contraction
    121021720 (CACNA1S)
  09156 Nervous system
   04727 GABAergic synapse
    121021720 (CACNA1S)
   04725 Cholinergic synapse
    121021720 (CACNA1S)
   04726 Serotonergic synapse
    121021720 (CACNA1S)
   04723 Retrograde endocannabinoid signaling
    121021720 (CACNA1S)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    121021720 (CACNA1S)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121021720 (CACNA1S)
   05020 Prion disease
    121021720 (CACNA1S)
   05022 Pathways of neurodegeneration - multiple diseases
    121021720 (CACNA1S)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    121021720 (CACNA1S)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    121021720 (CACNA1S)
   05414 Dilated cardiomyopathy
    121021720 (CACNA1S)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    121021720 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pyu04040]
    121021720 (CACNA1S)
Ion channels [BR:pyu04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   121021720 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 121021720
NCBI-ProteinID: XP_040318279
LinkDB
Position
Unknown
AA seq 1871 aa
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSRVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTVEML
LKMCGLGLRQYFMSIFNRFDCFVVCSGILELLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDTGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFVSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFMERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANVACDNSSHSNSQL
FSSIRYEREFPGETEMPAARGGAFGRPQSVLGAHSKSCVEKLKGQLAQREMPGAQASPTP
CQHAGAEPPLPGERRDPTPGPEEASHHGRTKESSSRCQTPATARLIQEALVRGGLDTLAA
DADFVTVTGRALADACQMEPEDVEVAATELLKRQESPEGMASAQGRLSLGSSLGSLDQHQ
GSQETLIPRRL
NT seq 5616 nt   +upstreamnt  +downstreamnt
atggagccatcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaaccccctg
aggaaggcctgcatcaacatcgtggaatggaaaccgttcgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccagaagatgacaacaac
actctcaaccttggtctggagaaactggagtatttcttcctcatcgtcttctcaatcgaa
gccgccatgaagatcattgcctatggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaatgtgctagacttcatcatcgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacaccgccccgatgagcagcaaaggggctggcctggac
gtcaaggccctgagagccttccgtgtgctcagacccctccggcttgtgtcgggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgcttcccctgttccacatcgcc
ctgcttgtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattgggacagatatcgtggccacggtagagaatgag
aagccctcaccctgcgccaggacgggctcgggacgcccgtgcaccatcaacggcagcgag
tgtcggggcggctggccggggcccaaccacggcatcacgcactttgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggaa
gaggacctccggggctacatgagctggatcacgcagggggaggtcatggacgtcgaggac
ttgagagaagggaagctgtctctggatgaaggaggctccgacacagagagcctgtatgaa
atcgagggcttgaacaaaatcatccagtttgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccacgatgtgatcaagtccagagtcttctattggctggtgatcctg
gtcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggttg
acccatttgcaagacgttgccaaccgcgtgctgctggcccttttcaccgtcgagatgctg
ctgaagatgtgcgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagctgctgctggtggagtcaggtgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctactgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgcttttcctcttcatcgtcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacacggaggtgcggcgcagcaactttgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctaacaggtgaagactggaattctgtgatg
tacaacgggatcatggcctacggcgggccgtcctaccctggggtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggcaattatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggcagagagcctgacttctgcccagaaggccaaagctgaggag
aaaaaacgcaggaagatgtccaagggtcttccagataagtcagaggaagagaagtcagtg
atggccaagaagctggaacagaaacccaagggtgaaggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtgaaggatccctacccctcagctgac
ttcccaggagatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgcccg
ctggctgagctgcagctcaaagagaaggcagtgcccatcccagaagccagctccttcttc
attttcagccccaccaacaagatccgtgtcttgtgtcatcgcattgtcaacgctacctgg
ttcaccaacttcatccttcttttcatcctgctcagcagtgccgcactggccgcggaggac
cccatccgggccgagtccgtgaggaatcagatccttgggtatttcgacattgcgttcacc
tctgtcttcaccgtggagattgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccggcccctgcgggccatcaacagagccaaggggctgaagcacgtggtgcagtgt
gtgtttgtggccatccgcacaatcgggaacatcgtcctcgtcaccaccctcctgcagttc
atgtttgcctgcatcggcgtccagcttttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acccagatggagctgcgcccccgccagtggatacacagcgacttccatttcgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacctttgagggatggcctcagctgctt
taccaggccatagactcatacaaggaagacacaggccccatctacaacaaccgagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaactgtgaa
ctggacaaaaaccagcgccagtgtgtgcaatatgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtatgtcgtcacctcctcctacttt
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaacgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgatgtcattctcagt
gaaatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagcgcccggatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcagagggagtgcgcactctgctgtggacgttc
atcaagtccttccaggccctgccatacgtggccctgctcatcgtcatgctcttcttcatc
tacgccgtcatcggcatgcagatgtttggtaagatcgccatggtggatgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgttgctgctcttcaggtgtgcg
acaggtgaggcgtggcaggagatcctcctggcctgcagctacggcaagttgtgtgacccc
gaatcggattatgccccgggtgaggagtacacgtgtggcaccaacttcgcctactattac
ttcgtcagcttctacatgctctgcgccttcctgatcatcaacctgtttgtagctgtcatc
atggacaactttgactacctcacccgggactggtccatcctgggcccccatcacctggat
gagttcaaagccatttgggcagagtatgacccagaggctaagggcagaatcaaacacctg
gatgtggtgaccctgctgagacggatccaaccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccttgaacagcgatggcacg
gtcaccttcaacgccactctcttcgccctggtccgcacagcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactgtacagatccaggccggactgcgg
accattgaggaagaggcagccccagagatccggcgcaccatctcaggagacctgacagct
gaagaggagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actgggggcctgtttggccaggtggacaacttcatggaaaggaccaactccctgccccct
gtcatggccaaccagcgacccctccagtttgctgagatagagatggaagagctggaatca
cccgtcttcttggaggatttccctcaagatccacgcaccaaccctcttgctcatgccaac
accaataatgccaatgccaatgttgcctgtgacaatagcagccatagcaacagccagcta
ttttccagcatccgctatgaaagggagttccctggagagacagagatgcctgctgccaga
ggaggagcctttggccggccccaaagcgtcctgggagcccacagcaaatcctgtgtggaa
aagctaaaaggacagctggcccagagagaaatgcctggggcccaggcgtctcctaccccc
tgccagcatgctggcgcagagcctcccctgcctggggagaggagggaccccaccccgggg
cctgaggaagcatcccaccacggtaggaccaaggagagtagttccaggtgccagactcca
gcgacagccaggctgatacaggaggctctggttcgaggaggcctggacaccttggcggct
gatgctgactttgtcacggtgacaggccgggccctggcagatgcctgccagatggaacca
gaggatgtggaggtggcagcaacagagctactgaaaagacaagagtccccagagggcatg
gccagtgcccagggacgcttgagcctcgggtcctcgctggggagccttgaccagcatcag
ggctcccaggagaccctgatcccccgcaggctgtga

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