Herpailurus yagouaroundi (jaguarundi): 121021720
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Entry
121021720 CDS
T07555
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu04010
MAPK signaling pathway
pyu04020
Calcium signaling pathway
pyu04022
cGMP-PKG signaling pathway
pyu04024
cAMP signaling pathway
pyu04260
Cardiac muscle contraction
pyu04261
Adrenergic signaling in cardiomyocytes
pyu04270
Vascular smooth muscle contraction
pyu04723
Retrograde endocannabinoid signaling
pyu04725
Cholinergic synapse
pyu04726
Serotonergic synapse
pyu04727
GABAergic synapse
pyu04911
Insulin secretion
pyu04912
GnRH signaling pathway
pyu04921
Oxytocin signaling pathway
pyu04924
Renin secretion
pyu04925
Aldosterone synthesis and secretion
pyu04927
Cortisol synthesis and secretion
pyu04929
GnRH secretion
pyu04934
Cushing syndrome
pyu04935
Growth hormone synthesis, secretion and action
pyu05010
Alzheimer disease
pyu05020
Prion disease
pyu05022
Pathways of neurodegeneration - multiple diseases
pyu05207
Chemical carcinogenesis - receptor activation
pyu05410
Hypertrophic cardiomyopathy
pyu05412
Arrhythmogenic right ventricular cardiomyopathy
pyu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121021720 (CACNA1S)
04020 Calcium signaling pathway
121021720 (CACNA1S)
04024 cAMP signaling pathway
121021720 (CACNA1S)
04022 cGMP-PKG signaling pathway
121021720 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
121021720 (CACNA1S)
04929 GnRH secretion
121021720 (CACNA1S)
04912 GnRH signaling pathway
121021720 (CACNA1S)
04921 Oxytocin signaling pathway
121021720 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
121021720 (CACNA1S)
04924 Renin secretion
121021720 (CACNA1S)
04925 Aldosterone synthesis and secretion
121021720 (CACNA1S)
04927 Cortisol synthesis and secretion
121021720 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
121021720 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
121021720 (CACNA1S)
04270 Vascular smooth muscle contraction
121021720 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
121021720 (CACNA1S)
04725 Cholinergic synapse
121021720 (CACNA1S)
04726 Serotonergic synapse
121021720 (CACNA1S)
04723 Retrograde endocannabinoid signaling
121021720 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
121021720 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
121021720 (CACNA1S)
05020 Prion disease
121021720 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
121021720 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
121021720 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
121021720 (CACNA1S)
05414 Dilated cardiomyopathy
121021720 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
121021720 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pyu04040
]
121021720 (CACNA1S)
Ion channels [BR:
pyu04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
121021720 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
121021720
NCBI-ProteinID:
XP_040318279
LinkDB
All DBs
Position
Unknown
AA seq
1871 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSRVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTVEML
LKMCGLGLRQYFMSIFNRFDCFVVCSGILELLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDTGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFVSFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFMERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANVACDNSSHSNSQL
FSSIRYEREFPGETEMPAARGGAFGRPQSVLGAHSKSCVEKLKGQLAQREMPGAQASPTP
CQHAGAEPPLPGERRDPTPGPEEASHHGRTKESSSRCQTPATARLIQEALVRGGLDTLAA
DADFVTVTGRALADACQMEPEDVEVAATELLKRQESPEGMASAQGRLSLGSSLGSLDQHQ
GSQETLIPRRL
NT seq
5616 nt
NT seq
+upstream
nt +downstream
nt
atggagccatcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaaccccctg
aggaaggcctgcatcaacatcgtggaatggaaaccgttcgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccagaagatgacaacaac
actctcaaccttggtctggagaaactggagtatttcttcctcatcgtcttctcaatcgaa
gccgccatgaagatcattgcctatggcttcctgttccaccaggatgcctacctgcgcagc
ggctggaatgtgctagacttcatcatcgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacaccgccccgatgagcagcaaaggggctggcctggac
gtcaaggccctgagagccttccgtgtgctcagacccctccggcttgtgtcgggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgcttcccctgttccacatcgcc
ctgcttgtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattgggacagatatcgtggccacggtagagaatgag
aagccctcaccctgcgccaggacgggctcgggacgcccgtgcaccatcaacggcagcgag
tgtcggggcggctggccggggcccaaccacggcatcacgcactttgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggaa
gaggacctccggggctacatgagctggatcacgcagggggaggtcatggacgtcgaggac
ttgagagaagggaagctgtctctggatgaaggaggctccgacacagagagcctgtatgaa
atcgagggcttgaacaaaatcatccagtttgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccacgatgtgatcaagtccagagtcttctattggctggtgatcctg
gtcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggttg
acccatttgcaagacgttgccaaccgcgtgctgctggcccttttcaccgtcgagatgctg
ctgaagatgtgcgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagctgctgctggtggagtcaggtgccatgacg
cccctgggcatctccgtgctgcgctgcatccgcctactgcggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgcttttcctcttcatcgtcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtacgacttcgaggacacggaggtgcggcgcagcaactttgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctaacaggtgaagactggaattctgtgatg
tacaacgggatcatggcctacggcgggccgtcctaccctggggtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggcaattatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggcagagagcctgacttctgcccagaaggccaaagctgaggag
aaaaaacgcaggaagatgtccaagggtcttccagataagtcagaggaagagaagtcagtg
atggccaagaagctggaacagaaacccaagggtgaaggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagtgaaggatccctacccctcagctgac
ttcccaggagatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgcccg
ctggctgagctgcagctcaaagagaaggcagtgcccatcccagaagccagctccttcttc
attttcagccccaccaacaagatccgtgtcttgtgtcatcgcattgtcaacgctacctgg
ttcaccaacttcatccttcttttcatcctgctcagcagtgccgcactggccgcggaggac
cccatccgggccgagtccgtgaggaatcagatccttgggtatttcgacattgcgttcacc
tctgtcttcaccgtggagattgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggactcgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccggcccctgcgggccatcaacagagccaaggggctgaagcacgtggtgcagtgt
gtgtttgtggccatccgcacaatcgggaacatcgtcctcgtcaccaccctcctgcagttc
atgtttgcctgcatcggcgtccagcttttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagagaaggagtgcaggggctattactatgtgtacaaggatggggacccc
acccagatggagctgcgcccccgccagtggatacacagcgacttccatttcgacaacgtg
ctctcggccatgatgtcactcttcacggtctccacctttgagggatggcctcagctgctt
taccaggccatagactcatacaaggaagacacaggccccatctacaacaaccgagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaactgtgaa
ctggacaaaaaccagcgccagtgtgtgcaatatgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtatgtcgtcacctcctcctacttt
gagtacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaacgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgatgtcattctcagt
gaaatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagcgcccggatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcagagggagtgcgcactctgctgtggacgttc
atcaagtccttccaggccctgccatacgtggccctgctcatcgtcatgctcttcttcatc
tacgccgtcatcggcatgcagatgtttggtaagatcgccatggtggatgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgttgctgctcttcaggtgtgcg
acaggtgaggcgtggcaggagatcctcctggcctgcagctacggcaagttgtgtgacccc
gaatcggattatgccccgggtgaggagtacacgtgtggcaccaacttcgcctactattac
ttcgtcagcttctacatgctctgcgccttcctgatcatcaacctgtttgtagctgtcatc
atggacaactttgactacctcacccgggactggtccatcctgggcccccatcacctggat
gagttcaaagccatttgggcagagtatgacccagaggctaagggcagaatcaaacacctg
gatgtggtgaccctgctgagacggatccaaccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccttgaacagcgatggcacg
gtcaccttcaacgccactctcttcgccctggtccgcacagcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactgtacagatccaggccggactgcgg
accattgaggaagaggcagccccagagatccggcgcaccatctcaggagacctgacagct
gaagaggagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actgggggcctgtttggccaggtggacaacttcatggaaaggaccaactccctgccccct
gtcatggccaaccagcgacccctccagtttgctgagatagagatggaagagctggaatca
cccgtcttcttggaggatttccctcaagatccacgcaccaaccctcttgctcatgccaac
accaataatgccaatgccaatgttgcctgtgacaatagcagccatagcaacagccagcta
ttttccagcatccgctatgaaagggagttccctggagagacagagatgcctgctgccaga
ggaggagcctttggccggccccaaagcgtcctgggagcccacagcaaatcctgtgtggaa
aagctaaaaggacagctggcccagagagaaatgcctggggcccaggcgtctcctaccccc
tgccagcatgctggcgcagagcctcccctgcctggggagaggagggaccccaccccgggg
cctgaggaagcatcccaccacggtaggaccaaggagagtagttccaggtgccagactcca
gcgacagccaggctgatacaggaggctctggttcgaggaggcctggacaccttggcggct
gatgctgactttgtcacggtgacaggccgggccctggcagatgcctgccagatggaacca
gaggatgtggaggtggcagcaacagagctactgaaaagacaagagtccccagagggcatg
gccagtgcccagggacgcttgagcctcgggtcctcgctggggagccttgaccagcatcag
ggctcccaggagaccctgatcccccgcaggctgtga
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integrated database retrieval system