KEGG   Herpailurus yagouaroundi (jaguarundi): 121023937
Entry
121023937         CDS       T07555                                 
Symbol
PLCB3
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pyu  Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu00562  Inositol phosphate metabolism
pyu01100  Metabolic pathways
pyu04015  Rap1 signaling pathway
pyu04020  Calcium signaling pathway
pyu04022  cGMP-PKG signaling pathway
pyu04062  Chemokine signaling pathway
pyu04070  Phosphatidylinositol signaling system
pyu04071  Sphingolipid signaling pathway
pyu04072  Phospholipase D signaling pathway
pyu04081  Hormone signaling
pyu04082  Neuroactive ligand signaling
pyu04261  Adrenergic signaling in cardiomyocytes
pyu04270  Vascular smooth muscle contraction
pyu04310  Wnt signaling pathway
pyu04371  Apelin signaling pathway
pyu04540  Gap junction
pyu04611  Platelet activation
pyu04613  Neutrophil extracellular trap formation
pyu04621  NOD-like receptor signaling pathway
pyu04713  Circadian entrainment
pyu04720  Long-term potentiation
pyu04723  Retrograde endocannabinoid signaling
pyu04724  Glutamatergic synapse
pyu04725  Cholinergic synapse
pyu04726  Serotonergic synapse
pyu04728  Dopaminergic synapse
pyu04730  Long-term depression
pyu04742  Taste transduction
pyu04750  Inflammatory mediator regulation of TRP channels
pyu04911  Insulin secretion
pyu04912  GnRH signaling pathway
pyu04915  Estrogen signaling pathway
pyu04916  Melanogenesis
pyu04918  Thyroid hormone synthesis
pyu04919  Thyroid hormone signaling pathway
pyu04921  Oxytocin signaling pathway
pyu04922  Glucagon signaling pathway
pyu04924  Renin secretion
pyu04925  Aldosterone synthesis and secretion
pyu04926  Relaxin signaling pathway
pyu04927  Cortisol synthesis and secretion
pyu04928  Parathyroid hormone synthesis, secretion and action
pyu04929  GnRH secretion
pyu04933  AGE-RAGE signaling pathway in diabetic complications
pyu04934  Cushing syndrome
pyu04935  Growth hormone synthesis, secretion and action
pyu04961  Endocrine and other factor-regulated calcium reabsorption
pyu04970  Salivary secretion
pyu04971  Gastric acid secretion
pyu04972  Pancreatic secretion
pyu04973  Carbohydrate digestion and absorption
pyu05010  Alzheimer disease
pyu05016  Huntington disease
pyu05017  Spinocerebellar ataxia
pyu05022  Pathways of neurodegeneration - multiple diseases
pyu05142  Chagas disease
pyu05143  African trypanosomiasis
pyu05146  Amoebiasis
pyu05163  Human cytomegalovirus infection
pyu05200  Pathways in cancer
pyu05415  Diabetic cardiomyopathy
pyu05417  Lipid and atherosclerosis
Module
pyu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121023937 (PLCB3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    121023937 (PLCB3)
   04310 Wnt signaling pathway
    121023937 (PLCB3)
   04371 Apelin signaling pathway
    121023937 (PLCB3)
   04020 Calcium signaling pathway
    121023937 (PLCB3)
   04070 Phosphatidylinositol signaling system
    121023937 (PLCB3)
   04072 Phospholipase D signaling pathway
    121023937 (PLCB3)
   04071 Sphingolipid signaling pathway
    121023937 (PLCB3)
   04022 cGMP-PKG signaling pathway
    121023937 (PLCB3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    121023937 (PLCB3)
   04081 Hormone signaling
    121023937 (PLCB3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    121023937 (PLCB3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121023937 (PLCB3)
   04613 Neutrophil extracellular trap formation
    121023937 (PLCB3)
   04621 NOD-like receptor signaling pathway
    121023937 (PLCB3)
   04062 Chemokine signaling pathway
    121023937 (PLCB3)
  09152 Endocrine system
   04911 Insulin secretion
    121023937 (PLCB3)
   04922 Glucagon signaling pathway
    121023937 (PLCB3)
   04929 GnRH secretion
    121023937 (PLCB3)
   04912 GnRH signaling pathway
    121023937 (PLCB3)
   04915 Estrogen signaling pathway
    121023937 (PLCB3)
   04921 Oxytocin signaling pathway
    121023937 (PLCB3)
   04926 Relaxin signaling pathway
    121023937 (PLCB3)
   04935 Growth hormone synthesis, secretion and action
    121023937 (PLCB3)
   04918 Thyroid hormone synthesis
    121023937 (PLCB3)
   04919 Thyroid hormone signaling pathway
    121023937 (PLCB3)
   04928 Parathyroid hormone synthesis, secretion and action
    121023937 (PLCB3)
   04916 Melanogenesis
    121023937 (PLCB3)
   04924 Renin secretion
    121023937 (PLCB3)
   04925 Aldosterone synthesis and secretion
    121023937 (PLCB3)
   04927 Cortisol synthesis and secretion
    121023937 (PLCB3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121023937 (PLCB3)
   04270 Vascular smooth muscle contraction
    121023937 (PLCB3)
  09154 Digestive system
   04970 Salivary secretion
    121023937 (PLCB3)
   04971 Gastric acid secretion
    121023937 (PLCB3)
   04972 Pancreatic secretion
    121023937 (PLCB3)
   04973 Carbohydrate digestion and absorption
    121023937 (PLCB3)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    121023937 (PLCB3)
  09156 Nervous system
   04724 Glutamatergic synapse
    121023937 (PLCB3)
   04725 Cholinergic synapse
    121023937 (PLCB3)
   04728 Dopaminergic synapse
    121023937 (PLCB3)
   04726 Serotonergic synapse
    121023937 (PLCB3)
   04720 Long-term potentiation
    121023937 (PLCB3)
   04730 Long-term depression
    121023937 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    121023937 (PLCB3)
  09157 Sensory system
   04742 Taste transduction
    121023937 (PLCB3)
   04750 Inflammatory mediator regulation of TRP channels
    121023937 (PLCB3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    121023937 (PLCB3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121023937 (PLCB3)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    121023937 (PLCB3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    121023937 (PLCB3)
   05142 Chagas disease
    121023937 (PLCB3)
   05143 African trypanosomiasis
    121023937 (PLCB3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121023937 (PLCB3)
   05016 Huntington disease
    121023937 (PLCB3)
   05017 Spinocerebellar ataxia
    121023937 (PLCB3)
   05022 Pathways of neurodegeneration - multiple diseases
    121023937 (PLCB3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121023937 (PLCB3)
   05415 Diabetic cardiomyopathy
    121023937 (PLCB3)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    121023937 (PLCB3)
   04934 Cushing syndrome
    121023937 (PLCB3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pyu04131]
    121023937 (PLCB3)
Enzymes [BR:pyu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121023937 (PLCB3)
Membrane trafficking [BR:pyu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121023937 (PLCB3)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121023937 (PLCB3)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 121023937
NCBI-ProteinID: XP_040322117
LinkDB
Position
Unknown
AA seq 1249 aa
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTAKVWTEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHQPSTGVPNS
SIRKRPLEQSNSALSESSAATEPSSSQLGSPSSDSCLGLSNGEELGLEKPSLEPRKSLGE
EGLQRGPDALGSADREDEEEDEEEEEQADPKKPTSDEGTASSEVNATEEMSTLVNYIEPV
KFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYM
PQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIV
DGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEH
FDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLI
YTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQVGPETCQETPSQQP
VTPNPTPSTLDISPRRPPGPATSPTSPSLSSPGQRDDLIASLLSEVAPAPLDELRGHKAL
VKLRSRQERELRELHKKHQRKAVALTRRLLDSLAQARAERRCRQRPGVLHRPPSPSPCDN
LSVTQRGSSCRGGEDEKAEEEEVKRYREFQKRQVQSLLELREAQADTEAERRLEHLRQAQ
QRLREIVLDAHATQFKRLKETNEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEIN
RRHITESVNSIRRLEEAQKQRHERLVAGQQQVLQQLAEEEPKLLAQLARECQEQRARLPQ
EACRSLLGETPEGLGDGHLVACASNGHAPGSGGHLSGADSESQEENTKL
NT seq 3750 nt   +upstreamnt  +downstreamnt
atggcgggcgccaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtagag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcttccagtcggaacctg
gtgaccctgcgtgtggaccccaatggcttcttcctgtactggacaggacccaacatggag
gtggacaccctggacatcagttccatcagggacacgcggacgggccgttatgcccgcctg
cccaaggaccccaagatccgagaggtgctgggctttggaggccctgacacccggctggag
gagaagttgatgacagtggtggccgggccagacccggtgaatacaacgttcttgaacttc
atggccgtgcaggatgacacagccaaggtctggaccgaggagctgttcaagctggctatg
aacatcctggctcagaacgcctcccggaacacctttctgagaaaagcatacaccaagctg
aagctgcaggtgaaccaggatggacggatcccagtgaagaacatcctgaagatgttctca
gcagataagaagcgcgtcgagactgcgctggaatcctgtggcctcaatttcaaccggagt
gagtccatccggcccgacgagttctccttggaaatcttcgagcggttcctaaataagctg
tgtctgcggccagacattgacaagatcctgctggagataggcgccaagggcaagccatac
ctgacgctggagcagctcatggacttcatcaaccagaagcaacgggacccgaggctcaac
gaagtgctgtatccacccctgcggccctcccaggcccggctgctcattgagaagtatgag
cccaaccagcagttcctggaacgagaccagatgtccatggagggcttcagccgctacctg
gggggtgaggagaatggaatcctgcccttggaggccctggatctgagcgcagacatgacc
cagccgctaagcgcctacttcatcaactcctcacacaacacctatctcacagcggggcag
ctggctgggacgtcgtcggtggagatgtaccggcaggcactgctctggggctgccgctgc
gtggagctggacgtgtggaaagggcggcccccggaggaggagccctttatcacccacggc
ttcaccatgaccaccgaggtgccgctgcgagacgtgctggaggccattgcggaaaccgcc
ttcaagacctcgccctaccctgtcatcctctccttcgagaaccacgtggactcggcaaag
cagcaggccaagatggccgagtactgtcgttcgatcttcggggacgcgctgctcatcgac
ccactggacaagtacccgctggccccaggcgtccccctgcccagcccccaggacctgatg
ggccgcatcctggtgaagaacaagaagcgacaccagcccagcactggtgtccccaacagc
tccattcgcaagcggccgctggagcagagcaactcggccctgagcgagagctctgccgcc
accgagccctcctcatctcagctcgggtcccccagctctgacagctgcctgggcctgagc
aatggggaagagctgggccttgagaagcccagcctggagcctcggaagtctctgggcgag
gaggggctacagcggggccctgatgctcttggatctgccgaccgtgaggatgaggaggaa
gacgaggaagaggaggaacaggcagatcccaaaaagccgacctcagatgagggcactgcc
agcagtgaagtcaatgccactgaggagatgtcaacactcgtcaactacatcgagcctgtc
aagttcaagtcctttgaggctgctcgaaagaggaacaaatgcttcgagatgtcatccttc
gtggaaaccaaggccatggagcaactgaccaagagccccatggagtttgtggaatacaat
aaacaacagctcagccgcatctaccccaagggcacccgcgtggactcctccaactacatg
ccccagctcttctggaacgtgggctgccagcttgtggccctcaactttcagaccctggat
gtggcgatgcagctcaacgcgggtgtgtttgagtacaacgggcgcagcggctacctgctc
aagcccgagttcatgcggcggccggacaagtccttcgaccccttcaccgaagtcatcgtg
gacggcatcgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctgtccgac
aggaaggtgggcatctacgtggaggtggacatgtttggcctccccgttgacacacggcgc
aaataccgcactcggacgtctcaggggaactcattcaatcctgtgtgggatgaggaacac
tttgacttccccaaggtggtgctccccacgctggcttcgctgcgcatcgcggcctttgag
gaaggcggcaagtttgtggggcatcggattctgcccgtctctgccatccgttcagggtac
cactacatttgcctgcggaacgaggccaaccagccgctctgcctgccagccctgctcata
tacaccgaagcctccgactacattcctgatgaccaccaggactacgcagaggccctgatc
aaccccatcaagcatgtcagcctgatggaccagagggccaagcagttggccgccctcatc
ggggagagcgaggctcaggttggcccagaaacgtgccaggagactccatctcagcagccg
gtgaccccaaaccccacacccagcacactggacatctccccgcgccggcccccgggcccc
gccacgtcccctaccagcccctccctcagcagcccagggcagcgcgacgacctcatcgcc
agcctcctctcagaggtggccccggccccgctggacgagctccgaggccacaaggctctg
gtgaaactccggagccggcaggagcgagagcttcgggagctgcacaagaagcatcagcgg
aaggcggttgccctcactcgccgattgctcgacagcttggcccaggcccgggctgagcgc
aggtgccggcagcggccgggtgtcctacaccgccctcccagcccgagtccctgtgacaac
ctgagtgtcacccagaggggttcttcctgcagaggcggggaggacgagaaggcggaggag
gaagaggtgaagcggtatcgagagttccagaagagacaggtgcagagtctgctggagctg
cgggaggcccaggcggatacagaggccgagcggaggctggagcatctgcgacaggctcag
cagcggctcagggagatcgtcctggatgctcacgccacccagttcaagcggctgaaggag
acgaacgagagggagaagaaggaactgcagaagattctggacaggaagcgccacaacagt
atctcagaagccaagacaagggagaaacataagaaggaggcggaactgacagagattaac
cgtcggcacatcaccgagtccgtcaactccatccgtcggctggaggaggcccagaagcag
cggcacgaacgccttgtggccgggcagcagcaggtgctgcagcagctagccgaagaagag
cccaagctgctggcccaactggcccgggagtgtcaggaacagcgggcaaggctgccccag
gaggcctgccggagcctgctgggcgagacgccggaggggctgggggacgggcatctggtg
gcctgtgccagcaatggtcacgcacctgggagcggcgggcacctgtctggcgctgactca
gagagccaagaggagaatacgaagctctga

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