KEGG   Puma yagouaroundi (jaguarundi): 121024518
Entry
121024518         CDS       T07555                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
pyu  Puma yagouaroundi (jaguarundi)
Pathway
pyu04120  Ubiquitin mediated proteolysis
pyu04380  Osteoclast differentiation
pyu04630  JAK-STAT signaling pathway
pyu04668  TNF signaling pathway
pyu04910  Insulin signaling pathway
pyu04917  Prolactin signaling pathway
pyu04920  Adipocytokine signaling pathway
pyu04930  Type II diabetes mellitus
pyu04931  Insulin resistance
pyu04932  Non-alcoholic fatty liver disease
pyu04935  Growth hormone synthesis, secretion and action
pyu05160  Hepatitis C
pyu05164  Influenza A
pyu05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    121024518 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    121024518 (SOCS3)
   04668 TNF signaling pathway
    121024518 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    121024518 (SOCS3)
   04920 Adipocytokine signaling pathway
    121024518 (SOCS3)
   04917 Prolactin signaling pathway
    121024518 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    121024518 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121024518 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    121024518 (SOCS3)
   05164 Influenza A
    121024518 (SOCS3)
   05168 Herpes simplex virus 1 infection
    121024518 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    121024518 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    121024518 (SOCS3)
   04931 Insulin resistance
    121024518 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:pyu04121]
    121024518 (SOCS3)
Ubiquitin system [BR:pyu04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     121024518 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 121024518
NCBI-ProteinID: XP_040322677
LinkDB
Position
Unknown
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPALPPPPAEPSSEVPEQPPAQPLAGSPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgacgggcggcgaggcgaacctgctgctc
agcgccgagcccgccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttttcgctgcagagcgacccccggagcacgcagccggtgccccgcttcgactgcgtg
ctcaagctggtgcaccactacatgccgccccccggcgcccccgccttgccccctccaccc
gccgaaccctcctccgaggtgccggagcagccgccggcccagccgctggcggggagtccc
cccaggagagcctattacatctactccgggggcgagaagatccctctggtgttgagccgg
cccctctcctccaacgtggccactctccaacatctctgtcggaagaccgtcaacggccac
ctggactcctatgagaaagtcacccagctgcctgggcccattcgggaattcctggaccag
tacgatgcccctctttaa

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