Herpailurus yagouaroundi (jaguarundi): 121025675
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Entry
121025675 CDS
T07555
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu00010
Glycolysis / Gluconeogenesis
pyu00020
Citrate cycle (TCA cycle)
pyu00620
Pyruvate metabolism
pyu00785
Lipoic acid metabolism
pyu01100
Metabolic pathways
pyu01200
Carbon metabolism
pyu01210
2-Oxocarboxylic acid metabolism
pyu04066
HIF-1 signaling pathway
pyu04922
Glucagon signaling pathway
pyu05230
Central carbon metabolism in cancer
pyu05415
Diabetic cardiomyopathy
Module
pyu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
121025675 (PDHA1)
00020 Citrate cycle (TCA cycle)
121025675 (PDHA1)
00620 Pyruvate metabolism
121025675 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
121025675 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
121025675 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
121025675 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
121025675 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
121025675 (PDHA1)
Enzymes [BR:
pyu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
121025675 (PDHA1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
121025675
NCBI-ProteinID:
XP_040324246
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgcagctgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccgactggaagagggccctcctgtcaccacggtactcaccagggaggat
gggctcaaatactataggatgatgcagactgttcgccgaatggaattaaaggcagatcag
ctgtataaacagaaaattattcgtggtttttgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggcttcacctttactcgtggactttctgtccgagaaattcttgcagagcttacagga
cgaagaggaggttgcgctaaagggaaaggcggatcgatgcatatgtatgccaaaaacttc
tacgggggcaacggcatcgtcggagctcaggtgcccctgggagcagggattgctctggcc
tgtaagtataacggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaac
caaggtcagatattcgaagcttacaatatggcagctttgtggaaattgccatgtattttc
atctgtgaaaataaccgctatggaatgggaacatctgttgagagagcagcggccagcacg
gattactacaagagaggtgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggcgacgaggtttgcagccgcctactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgctaccacggacatagcatgagtgaccctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaacctggccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagagattgaggatgctgcccagtttgccaccgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgacccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
DBGET
integrated database retrieval system
