Herpailurus yagouaroundi (jaguarundi): 121029594
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Entry
121029594 CDS
T07555
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu00270
Cysteine and methionine metabolism
pyu00480
Glutathione metabolism
pyu01100
Metabolic pathways
pyu01240
Biosynthesis of cofactors
pyu04216
Ferroptosis
Module
pyu_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
121029594 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
121029594 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
121029594 (GCLC)
Enzymes [BR:
pyu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
121029594 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
121029594
NCBI-ProteinID:
XP_040329712
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPLEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFMETFPEDEEAARASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNTVVDGYGKVQNTSELTTEDYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFISNHPDYKGDSVITDEMNYS
LILKCNQIADELCECPELLGPAFRKVKYSGSKTDPSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataagagagtccagttggtcctgtctggagaagaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttac
atgattgaaggcacacctggacaaccgtacggaggaactatgtccgagttcaacacagtt
gaagacaacatgagaaaacgccggaaggaggcgacctctttattaggagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgccagagttt
aaacccaatccactcgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcatccccgcttcagtaccctaacaagaaatatccgacacaggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatggaaaca
tttcctgaggatgaggaggcagcaagggcttccaagcctgatcatatttacatggatgcc
atgggatttgggatgggtaattgctgtcttcaggtaacgttccaagcctgcagcatatcc
gaggccagatacctttatgatcagctggccaccatctgtccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
agctataggatcagtaaatcccgatatgattcaatagacagttatttatctgagtgtggg
gagaaatacaatgacatcgacttgacaattgataaagaaatctacgaacagctgctgcag
gaaggcattgatcatctcctggctcagcatgtcgctcatctcttcataagagacccactg
actctatttgaagagaaaatacacttggatgatgccaatgaatcagaccattttgagaac
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactctgacatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtgctgcttacaagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgatgaaaacatgaaagttgcacagaaacgagatgctgtcttg
cggggaatgttttatttcaggaaagatatttgcaaaggtgggaacactgtggtggatggc
tacgggaaggtccagaacacctcggaactgaccacggaggactacaccctgatgagcata
gacaccatcatcaacgggaaggagggtgtgtttcctgggttgatcccgattctgaactct
taccttgaaaacatggaggtggatgtggacactagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgccagatggatgagagagttt
atctcaaaccatcctgactataagggagacagtgtaatcactgatgaaatgaactatagc
ctcatcttaaagtgtaaccaaattgcagacgaattgtgtgagtgcccggagttacttgga
ccagcttttaggaaagtgaaatacagtggaagtaaaacggacccttccaactga
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