KEGG   Puma yagouaroundi (jaguarundi): 121031929
Entry
121031929         CDS       T07555                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pyu  Puma yagouaroundi (jaguarundi)
Pathway
pyu04010  MAPK signaling pathway
pyu04020  Calcium signaling pathway
pyu04022  cGMP-PKG signaling pathway
pyu04114  Oocyte meiosis
pyu04218  Cellular senescence
pyu04310  Wnt signaling pathway
pyu04360  Axon guidance
pyu04370  VEGF signaling pathway
pyu04380  Osteoclast differentiation
pyu04625  C-type lectin receptor signaling pathway
pyu04650  Natural killer cell mediated cytotoxicity
pyu04658  Th1 and Th2 cell differentiation
pyu04659  Th17 cell differentiation
pyu04660  T cell receptor signaling pathway
pyu04662  B cell receptor signaling pathway
pyu04720  Long-term potentiation
pyu04724  Glutamatergic synapse
pyu04728  Dopaminergic synapse
pyu04921  Oxytocin signaling pathway
pyu04922  Glucagon signaling pathway
pyu04924  Renin secretion
pyu05010  Alzheimer disease
pyu05014  Amyotrophic lateral sclerosis
pyu05020  Prion disease
pyu05022  Pathways of neurodegeneration - multiple diseases
pyu05031  Amphetamine addiction
pyu05152  Tuberculosis
pyu05163  Human cytomegalovirus infection
pyu05166  Human T-cell leukemia virus 1 infection
pyu05167  Kaposi sarcoma-associated herpesvirus infection
pyu05170  Human immunodeficiency virus 1 infection
pyu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pyu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121031929 (PPP3CA)
   04310 Wnt signaling pathway
    121031929 (PPP3CA)
   04370 VEGF signaling pathway
    121031929 (PPP3CA)
   04020 Calcium signaling pathway
    121031929 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    121031929 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    121031929 (PPP3CA)
   04218 Cellular senescence
    121031929 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    121031929 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    121031929 (PPP3CA)
   04660 T cell receptor signaling pathway
    121031929 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    121031929 (PPP3CA)
   04659 Th17 cell differentiation
    121031929 (PPP3CA)
   04662 B cell receptor signaling pathway
    121031929 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    121031929 (PPP3CA)
   04921 Oxytocin signaling pathway
    121031929 (PPP3CA)
   04924 Renin secretion
    121031929 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    121031929 (PPP3CA)
   04728 Dopaminergic synapse
    121031929 (PPP3CA)
   04720 Long-term potentiation
    121031929 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    121031929 (PPP3CA)
   04380 Osteoclast differentiation
    121031929 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121031929 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121031929 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    121031929 (PPP3CA)
   05163 Human cytomegalovirus infection
    121031929 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121031929 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    121031929 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121031929 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    121031929 (PPP3CA)
   05020 Prion disease
    121031929 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    121031929 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    121031929 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121031929 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pyu01009]
    121031929 (PPP3CA)
Enzymes [BR:pyu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     121031929 (PPP3CA)
Protein phosphatases and associated proteins [BR:pyu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     121031929 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 121031929
NCBI-ProteinID: XP_040333375
LinkDB
Position
Unknown
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccgacttacagcaaaagaagtattcgataacgatgggaag
cctcgtgtggatatcttaaaggcacatctcatgaaggagggcaggctggaagagagtgtt
gcattgagaataataacagagggggcctcaattcttcgacaggaaaaaaatttgctggat
atcgatgcaccagtcacagtttgtggggacatccatggacaattctttgacttgatgaag
ctttttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagaacgcgtatatgatgcctgtatggat
gcctttgactgcctgcccctggctgccctgatgaaccaacagttcctgtgtgtccacggc
ggtttgtctccagagattaacactttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcgtacttctac
agctacccggctgtatgtgaattcttacagcacaataacctgttgtctatactccgagcc
catgaagcccaagatgcagggtatcgcatgtacaggaaaagccaaacgacaggcttccct
tctctaattacaattttttcagcaccaaattacttagatgtgtacaataacaaagctgca
gtattgaagtatgagaacaatgtcatgaacatcaggcaattcaactgttctcctcaccca
tactggcttccaaatttcatggatgttttcacttggtccctgccctttgttggagaaaaa
gtgactgaaatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaagatggatttgatggcgcaacagctgcagcccggaaggaggtgataaggaacaagatc
cgagcaataggcaaaatggcccgagtgttctcagttctcagagaagagagtgagagcgtg
ctaacgctgaaaggcttgactcccacgggcatgctccccagcggagtgctttctggaggg
aagcagaccctgcaaagcgctactgttgaggctattgaggctgatgaagccatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccacctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcgcctcagagactaacggcacggacagcaatggcagtaatagcagcaatatc
cagtga

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