Puma yagouaroundi (jaguarundi): 121034896 Help Entry 121034896         CDS       T07555                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu04064   NF-kappa B signaling pathway pyu04066   HIF-1 signaling pathway pyu04145   Phagosome pyu04151   PI3K-Akt signaling pathway pyu04217   Necroptosis pyu04613   Neutrophil extracellular trap formation pyu04620   Toll-like receptor signaling pathway pyu04621   NOD-like receptor signaling pathway pyu04936   Alcoholic liver disease pyu05132   Salmonella infection pyu05133   Pertussis pyu05134   Legionellosis pyu05135   Yersinia infection pyu05140   Leishmaniasis pyu05142   Chagas disease pyu05144   Malaria pyu05145   Toxoplasmosis pyu05146   Amoebiasis pyu05152   Tuberculosis pyu05161   Hepatitis B pyu05162   Measles pyu05164   Influenza A pyu05170   Human immunodeficiency virus 1 infection pyu05171   Coronavirus disease - COVID-19 pyu05205   Proteoglycans in cancer pyu05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pyu05321   Inflammatory bowel disease pyu05323   Rheumatoid arthritis pyu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pyu00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     121034896 (TLR4)    04066 HIF-1 signaling pathway     121034896 (TLR4)    04151 PI3K-Akt signaling pathway     121034896 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     121034896 (TLR4)   09143 Cell growth and death    04217 Necroptosis     121034896 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     121034896 (TLR4)    04620 Toll-like receptor signaling pathway     121034896 (TLR4)    04621 NOD-like receptor signaling pathway     121034896 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     121034896 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     121034896 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     121034896 (TLR4)    05161 Hepatitis B     121034896 (TLR4)    05171 Coronavirus disease - COVID-19     121034896 (TLR4)    05164 Influenza A     121034896 (TLR4)    05162 Measles     121034896 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     121034896 (TLR4)    05135 Yersinia infection     121034896 (TLR4)    05133 Pertussis     121034896 (TLR4)    05134 Legionellosis     121034896 (TLR4)    05152 Tuberculosis     121034896 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     121034896 (TLR4)    05144 Malaria     121034896 (TLR4)    05145 Toxoplasmosis     121034896 (TLR4)    05140 Leishmaniasis     121034896 (TLR4)    05142 Chagas disease     121034896 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     121034896 (TLR4)    05321 Inflammatory bowel disease     121034896 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     121034896 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     121034896 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pyu04131]     121034896 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:pyu04054]     121034896 (TLR4)    04090 CD molecules [BR:pyu04090]     121034896 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:pyu00536]     121034896 (TLR4) Membrane trafficking [BR:pyu04131]  Endocytosis   Phagocytosis    Toll-like receptors     121034896 (TLR4) Pattern recognition receptors [BR:pyu04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    121034896 (TLR4) CD molecules [BR:pyu04090]  Proteins   121034896 (TLR4) Glycosaminoglycan binding proteins [BR:pyu00536]  Hyaluronan   Cell surface receptors    121034896 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_9 LRR_NXF1-5 LRR_6 LRR_At5g56370 ThsB_TIR LRR_R13L1-DRL21 LRR_EndoS Motif Other DBs NCBI-GeneID:  121034896 NCBI-ProteinID:  XP_040338053 LinkDB All DBs Position Unknown AA seq 833 aa AA seqDB search MMPPTRLAGTLIPAMAFLSCLRPESWDPCVEVVPNITYQCMDLNLHKIPDNIPSSTKDLD MSFNPLRNLGSHSFSKFPELQVLDLSRCEIQIIEDDAYQGLNHLSILILTGNPIQRLFPG AFSGLSSLQTLVVVETNIASLEDFPIGHLKTLKELNVAHNLIHSFKLPEYLSNMPNLEYL DLSNNKIQNIYHKDLQVLRQKPLLNLSLDLSLNPLDFIQPGAFKEIKLHELILRSNFNST DVMKASIQGLAGLQIHQLVLGEFKNERNLERFDKSILEGLCNLIIEKFRIAYFHKFSEDA TDSFNCLANVSTISLVHLYFNGLKQLPKNLGWQRLELVNCEFEQFPTWKLDSLKELVFSA NKVGNTFTQVKLESLEFLDLSRNDFSFKSCCSERDLGTTRLKHLDLSFNNIITMSSNFLG LEQLEYLDFQHSSLKQVSDFSVFLPLKNLRYLDISYTHTQVAFHGIFNGLISLQILKMAG NSFQDNFLPNIFMELTNLTILDLSDCQLEQVSQVAFNSLPKLQLLNMSHNHLLSLDTLPY EPLHSLQTLDCSFNRIVASKEQELRHFPSNLSSLNLTRNDFACVCEHQSFLQWVKDQRQL LVEVEQMVCAKPLDMQGMPMLNFRNATCQVRKTIITVSVFTVLLVSLVVVLVYKFYFHLM LLAGCKKYSRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA ANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLL RQQVELYRLLNRNTYLEWEDSVLGRHIFWRRLRKALLDGKPRSPEGMADAEGS NT seq 2502 nt NT seq  +upstreamnt  +downstreamnt atgatgcctcctacccgcctggctgggactctgatcccagccatggccttcctctcctgc ctgagacctgagagctgggacccttgtgtggaggtggttcctaacattacttaccaatgc atggacctgaatcttcacaaaatccccgacaacatcccctcatcaaccaaggacctggac atgagctttaaccccctgagaaatttaggcagccatagtttctccaagttcccagaactg caggtgctggatttatccaggtgtgaaattcaaataattgaagatgatgcatatcagggc ctaaaccacctctccatcttgatattgacaggaaatcctatccagaggttattcccagga gctttttctggactatcaagtttacagacgctggtggttgtggagacaaatatagcatct ctagaggacttccccattggacatctcaaaacgttgaaggagcttaatgtggctcacaat cttatccattccttcaaattacctgaatatttatctaacatgcccaaccttgagtatttg gatctttccaataacaagatccaaaatatttatcataaagacttacaggttctacgtcaa aagcctctactcaacctttctttagacttgtccctaaaccctttagactttatccaacca ggtgcctttaaagaaattaagctccatgaactgattttgagaagtaattttaatagtaca gatgtaatgaaagcttctattcaaggtctggcaggtttacagatccatcagttggttctg ggagaatttaaaaatgaaaggaacttggaaagatttgacaaatctatcctggagggactg tgcaatttgatcatagaaaaattccggatagcatactttcacaagttctcagaggatgct actgactcatttaattgtttggcaaacgtttctaccatttctctggtgcatctgtatttc aacgggttaaaacagctccctaaaaatctcggatggcaacggttagaattggttaactgt gaatttgaacaatttcccacatggaagctggactctctcaaggagcttgttttctctgcc aacaaagttgggaacacttttactcaggttaagttggaaagccttgagtttctagatctc agtagaaatgactttagtttcaagagttgctgttctgagagagatttggggacaaccaga ctgaagcatttagatctaagcttcaacaatattattaccatgagttcaaacttcttgggc ttagaacagttagaatatctagacttccagcattccagtttgaaacaggtcagtgatttt tcagtattcctacccctcaaaaacctccgttaccttgatatttcttacactcacacccaa gttgccttccatggcatcttcaatggcttgatcagcctccaaatcttaaaaatggctggc aattctttccaggacaacttccttccaaatattttcatggagctgactaacttgaccatt ctagacctctctgattgtcagctggaacaggtgtcccaagtggcatttaactcactccct aaacttcagttgctaaatatgagtcacaatcacctcttatcattggatacacttccttat gaacctcttcactccctccagactctggactgcagttttaatcgtatagtggcctctaag gaacaagaactacggcattttccaagtaatctatcttccttaaatcttactcggaatgat tttgcttgtgtttgtgaacaccagagtttcctgcagtgggtcaaggaccagaggcagctc ttggtggaagttgaacagatggtgtgtgcaaaacctttggacatgcagggcatgcccatg ctgaattttaggaatgctacctgtcaggtgagaaagaccatcattactgtgtcggttttc actgtactcttggtttctctggtggtggttctggtgtataagttctatttccacctgatg cttcttgctggctgtaaaaagtatagcagaggtgaaagcacctatgacgccttcgttatc tactcaagccaggatgaagattgggtgaggaatgaattggtaaagaacttggaggagggg gtgcccccttttcagctctgccttcactacagagactttattcctggtgtggccattgcc gccaacatcatccaggaaggtttccataaaagccggaaggttatcgtcgtggtgtcccag cactttatccagagtcgatggtgcatctttgagtatgagattgcccagacttggcagttt ctgagcagccgtgccggcatcatcttcatcgtcctgcagaagttggagaagtccctgctg cggcagcaggtggagctgtatcgccttctcaacaggaacacctacctggagtgggaggac agtgtcctggggaggcacatcttctggagacgactcagaaaagccttgctggatggtaaa ccacgcagtccagaaggaatggcagatgcagaaggcagctag

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