Herpailurus yagouaroundi (jaguarundi): 121035030
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Entry
121035030 CDS
T07555
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu00790
Folate biosynthesis
pyu01100
Metabolic pathways
pyu01240
Biosynthesis of cofactors
pyu01523
Antifolate resistance
pyu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
121035030 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
121035030 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121035030 (FPGS)
Enzymes [BR:
pyu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
121035030 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
121035030
NCBI-ProteinID:
XP_040338347
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All DBs
Position
Unknown
AA seq
580 aa
AA seq
DB search
MSQARRHLRPALFLAAVSARVATTGVAARRGLSAWPAPQEPGMEYQDAVRALNTLQTNAG
YLEQVKRQRGDPQAQLEAMKLYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWPLYHRLEETKDSSSYVSMPTYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSILGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDYRGIGELKVSRPSLLRQMPLAPVFQPTTHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSMQACVRWFHQALHRRQRPSRGSEVLVLLFNSTGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSTVGNADQQNFMVTLDQVLLRCLAHQQHWSRLDE
EQAGPEPGEPTSSLLAPHPPEPRSTSSLVFSCISHALLWISQGRDPVFQPPSPPQGLFAH
PVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgccgccacctgcgacccgctcttttcctggcggcggtttctgcgcgc
gttgcaactaccggggtagcggctcggcgagggttgagcgcgtggcccgccccgcaggag
cccggcatggagtatcaggatgctgtgcgcgcactgaacaccctgcagaccaatgctggc
tatctggagcaggtaaagcgccagcggggtgaccctcaggcacagctggaagccatgaag
ctgtacttggcacggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacttgtgcctttactgaacgtattctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccctgagctcttcaccaagcacttctggcccctctac
caccggctggaggagaccaaggacagcagcagctatgtctccatgcccacctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcattggtggcgcttacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggcatttcctctcttggcatcgaccacaccagcattctgggggacacagtggaggagatc
gcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcaccgtgctccagcct
gacggtcccctggcagtgctgagggaccgggcccagcagatctcatgtcctctctatctg
tgcccaccactggaagccctggaggaaggggggccgccgctgaccctgggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggctcgctgctggctacagcaa
aaggactaccggggcatcggggagctgaaggtgtccaggcccagtctcttgcggcagatg
cccctggcgcccgtgttccagcccacgacccacatgcggcatgggcttcgggacacggag
tggctgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggatggcgcg
cacaccgccagcagcatgcaggcctgcgtgcgctggttccaccaggcgctgcaccgccgc
cagaggccgagtcgcggctctgaggtgcttgtcctgcttttcaactccaccggagaccgg
gatcccgcagcactgctgaagctgctgcagccctgtcagtttgattatgctgttttctgc
cctaacctgacagaggtctcaactgttggcaatgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgccttgcacaccaacagcactggagccgcctggacgag
gagcaggccggcccggagcctggtgagcccacatcctcgctgctggctccccacccgccc
gagccccgtagcaccagctccctcgtcttcagctgcatctcccatgccttgctgtggatc
agtcaaggccgggaccctgtctttcagccacccagtcccccgcagggcctcttcgcccac
cctgtggcaggcagcggggccggcgtgctccgtgaggctgctgccatccacgtgctggtc
accggcagcctgcacctggtgggcggcgtcctgaagctgctggagccagccctgtcccag
tag
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