KEGG   Puma yagouaroundi (jaguarundi): 121037198
Entry
121037198         CDS       T07555                                 
Symbol
GSTO1
Name
(RefSeq) glutathione S-transferase omega-1 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
pyu  Puma yagouaroundi (jaguarundi)
Pathway
pyu00480  Glutathione metabolism
pyu00980  Metabolism of xenobiotics by cytochrome P450
pyu00982  Drug metabolism - cytochrome P450
pyu00983  Drug metabolism - other enzymes
pyu01100  Metabolic pathways
pyu01524  Platinum drug resistance
pyu05200  Pathways in cancer
pyu05204  Chemical carcinogenesis - DNA adducts
pyu05207  Chemical carcinogenesis - receptor activation
pyu05208  Chemical carcinogenesis - reactive oxygen species
pyu05225  Hepatocellular carcinoma
pyu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    121037198 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    121037198 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    121037198 (GSTO1)
   00983 Drug metabolism - other enzymes
    121037198 (GSTO1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121037198 (GSTO1)
   05204 Chemical carcinogenesis - DNA adducts
    121037198 (GSTO1)
   05207 Chemical carcinogenesis - receptor activation
    121037198 (GSTO1)
   05208 Chemical carcinogenesis - reactive oxygen species
    121037198 (GSTO1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    121037198 (GSTO1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    121037198 (GSTO1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    121037198 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pyu02000]
    121037198 (GSTO1)
Enzymes [BR:pyu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     121037198 (GSTO1)
Transporters [BR:pyu02000]
 Other transporters
  Pores ion channels [TC:1]
   121037198 (GSTO1)
SSDB
Motif
Pfam: GST_N_2 GST_N_3 GST_C_3 GST_C GST_N GST_C_2 VMAP-M15
Other DBs
NCBI-GeneID: 121037198
NCBI-ProteinID: XP_040342295
LinkDB
Position
Unknown
AA seq 351 aa
MGGMSLRVSSFFCGSGRGYLSWPASTLGHDQQLRCFSASSAKPGRPGLGGRVGWVRGCDF
PSGSWPQGRRVPACRGWEGDSGRRTPAFIKRLGPRGAGRAQPPPSWRPPPAGTSERRREG
SKDRGRGDVLPEPPAHPGSRARPALRRDVRRVSQEPSEGHEIININLKNKPEWFFTKNPF
GLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMVFELFSKVPPLVTS
FIRRQNEDGSGLKEELRKEFSKLEEVLTNKKTTFFGGNSLSMIDYLIWPWFERLEVLELN
ECVDHTPKLKLWMAAMREDPAVSSLLIEAKAFRGFLELYLQNSPEACDYGL
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggggggcatgtctctgagggtgtcgagcttcttctgtggctctggacgtgggtacctc
tcttggccagcgagtacactcgggcacgaccagcagctgcggtgttttagcgctagctct
gcaaaaccgggaaggccaggcctaggtgggcgcgttgggtgggtccgcggctgcgatttc
ccttcaggctcttggccgcaggggcggcgcgttccagcttgcagagggtgggaaggggat
tctggacgccgcacgccagctttcattaagcgcctggggccacgcggggccgggagagca
cagcccccgcccagctggcggccgcccccggcaggcacttctgagaggagaagagaaggg
agcaaggaccgagggaggggcgacgtacttcctgaaccgccggcacaccctgggtcgcga
gctcggcctgccctgcgccgcgatgtccggagggtcagccaggagcctagcgaagggcat
gaaatcatcaacatcaacctgaaaaataagcctgagtggttctttacgaagaatcccttt
ggtctggtgccagttctggaaaacagtcagggtcaactgatctatgaatctgccattact
tgtgagtacctggatgaagcatatccagggaagaagctgttgccagatgacccctatgag
aaagcttgccaaaagatggtctttgagttattttctaaggttccccctttggtaacaagc
ttcattagaagacaaaacgaagacggctctggcctaaaagaagaattgcgtaaagaattc
agcaagttagaggaggttctgaccaataagaagacaaccttctttggtggcaattctctt
tctatgattgattacctcatctggccctggtttgaacggctcgaagttctggagttaaat
gagtgtgtagatcacactccaaaacttaagctctggatggcagccatgagggaagatcct
gcagtgtcctccctcctcattgaggcgaaggcctttcgaggtttcttagagctctacttg
cagaacagccctgaggcctgtgattatgggctctga

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