Puma yagouaroundi (jaguarundi): 121040887
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Entry
121040887 CDS
T07555
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu00260
Glycine, serine and threonine metabolism
pyu00630
Glyoxylate and dicarboxylate metabolism
pyu00670
One carbon pool by folate
pyu01100
Metabolic pathways
pyu01200
Carbon metabolism
pyu01230
Biosynthesis of amino acids
pyu01240
Biosynthesis of cofactors
pyu01523
Antifolate resistance
pyu04981
Folate transport and metabolism
Module
pyu_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
121040887 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
121040887 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
121040887 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
121040887 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121040887 (SHMT2)
Enzymes [BR:
pyu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
121040887 (SHMT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
121040887
NCBI-ProteinID:
XP_040347590
LinkDB
All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRCGHLGRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGMQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLRDTETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatgtggtcatctgggc
aggatggccatacggtgccaacacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaagagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagagagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccttggggtcctgtctgaacaacaagtactcggagggttac
cctggcaagagatattatggaggagcagaggtagtggatgaaattgagctgctgtgtcag
cgccgggccttggaagcctttgacctggatcctgcacagtggggagtcaatgtccagcca
tactcaggctctccggctaatctggcggcctatacagcccttctgcagcctcatgaccga
atcatggggctggacttgcctgatgggggccatcttactcacggctacatgtctgatgtc
aagcggatctcggccacatccattttctttgagtctatgccctataagttaaatcccaaa
actggcctcatcgactatgaccagctggcactgaccgctcggcttttccgaccgcggctc
attatagctggtaccagtgcctacgctcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctcctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcacgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaaggggatgcaggctgtggac
cccaagaccggccgggagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcagggggggccccacaaccatgccattgctgcagtggctgtggccttaaag
caggcctgcacccccatgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggccgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaatcac
ctagtgctggtggacctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaacttgtatccatcacagccaacaagaacacctgtcccggagaccgaagtgccatcaca
cctgggggcctgcggctcggggccccagccttgacctctcgacagttccgtgaggatgac
ttccggagagttgtagactttatagatgaaggggtcaacatcggcttggaggtgaagagc
aaaactgccaaactccaggatttcaaatccttcctgctcagggacacagaaaccagtcat
cggctggccgacctccggcaacgggtggaacagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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