| Entry |
|
|---|
| Symbol |
GLS2
|
|---|
| Name |
(RefSeq) glutaminase liver isoform, mitochondrial isoform X1
|
|---|
| KO |
|
|---|
| Organism |
pyu Puma yagouaroundi (jaguarundi)
|
|---|
| Pathway |
| pyu00250 | Alanine, aspartate and glutamate metabolism |
| pyu04964 | Proximal tubule bicarbonate reclamation |
| pyu05230 | Central carbon metabolism in cancer |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:pyu00001]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
121040913 (GLS2)
00220 Arginine biosynthesis
121040913 (GLS2)
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
121040913 (GLS2)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
121040913 (GLS2)
09156 Nervous system
04724 Glutamatergic synapse
121040913 (GLS2)
04727 GABAergic synapse
121040913 (GLS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
121040913 (GLS2)
05230 Central carbon metabolism in cancer
121040913 (GLS2)
Enzymes [BR:pyu01000]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.2 glutaminase
121040913 (GLS2)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
Unknown
|
|---|
| AA seq |
602 aa
MRSMRALQNALSGAGSHCWLGGWGHLRRSPLLGGGVRHHLSEAAALGRETPHSHQPQHRD
HDSSESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSQMCRMVR
ESSSGGLLDRDLFQKCVSSNIVLLTQAFRKKFVIPDFEEFTSHVDRIFEDAKELTGGKVA
AYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHK
FVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAG
NEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESG
SVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGA
ILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGG
EVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE
ACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTPSETQAEAAAEALSKENLES
MV |
|---|
| NT seq |
1809 nt +upstreamnt +downstreamnt
atgcgctctatgagggctctgcagaatgcgctgagcggggccggcagtcactgctggctg
ggaggctggggtcacctgagacggagccctcttcttggcgggggcgtccggcaccacctc
agtgaggccgcggcgctgggcagagagacgccgcacagccaccagccgcagcaccgggat
catgattcatcagagagtggcatgctgtcgcgcctgggtgatctgctcttctacactatt
gctgagggacaggaacgaatccctatccacaagttcactactgcactgaaggccactgga
ctgcagacatcagatccccggcttcgggactgcatgagccagatgtgccgcatggttcgg
gagtccagcagtggtggcctcttggaccgagatctcttccaaaagtgtgtgagcagcaac
attgtgctcctgacccaggcattccgaaagaagtttgtcattcctgattttgaggagttc
acgagccatgtggatcgcatctttgaggatgccaaagagctcactggaggcaaagtggcg
gcctacatccctcagctggccaaatccaatccagacctgtggggtgtctccctgtgcact
gtggatggtcagcggcactccgtgggccacacaaagatccccttctgcctgcagtcttgt
gtgaagcccctcacctatgccatctccataagcaccctaggcactgactacgtgcacaag
tttgtgggcaaggagcccagtggcctacgttacaacaagctctctctcaatgaggaagga
atcccccataaccccatggtcaatgctggtgccattgttgtgagctccctgatcaagatg
gactgtaacaaagcagagaagtttgattttgtattacagtatctgaacaaaatggctggg
aacgaatacatgggtttcagcaatgctacattccagtcagagaaggaaacaggggatcgg
aattatgccattggctactatctaaaggaaaagaagtgctttcctaagggggtggacatg
atggctgcccttgatctctatttccagctgtgctccgtggaggtgacctgtgagtcaggc
agtgtcatggcagccaccctggccaatggcgggatctgccccatcacaggagagagcgtg
ctgagcgctgaagcagtgcgcaacaccctcagcctcatgcactcctgcggcatgtacgac
ttctcaggccagtttgccttccatgtgggcctgccagccaagtcagctgtgtcaggagcc
atcctcctagtagtacctaatgtcatgggaatgatgtgtctgtcacctccactggacaag
ctagggaacagccacaggggcatcagcttctgccagaagttggtgtctctcttcaatttc
cacaactacgacaacctgaggcactgtgctcggaagttagacccacggcgtgaaggggga
gaagttcggaacaagactgtggtgaacctattatttgctgcctatagtggagatgtctca
gctcttcgaaggtttgccttgtcagccatggacatggaacagaaagattatgactcccgc
acagccctgcatgttgctgcagctgaaggacacatcgaagttgttaaattcctgattgag
gcttgcaaagtgaatccttttgttaaggacaggtggggcaacattcccctggatgatgct
gtgcagttcaaccacctggaggtggtgaaactgcttcaggattaccaggactcctataca
ccatctgagactcaggccgaagcagcggccgaggccctgtccaaggagaacttagagagc
atggtgtga |
|---|
