Puma yagouaroundi (jaguarundi): 121042474
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Entry
121042474 CDS
T07555
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu01521
EGFR tyrosine kinase inhibitor resistance
pyu01522
Endocrine resistance
pyu04010
MAPK signaling pathway
pyu04014
Ras signaling pathway
pyu04015
Rap1 signaling pathway
pyu04066
HIF-1 signaling pathway
pyu04068
FoxO signaling pathway
pyu04081
Hormone signaling
pyu04114
Oocyte meiosis
pyu04140
Autophagy - animal
pyu04144
Endocytosis
pyu04150
mTOR signaling pathway
pyu04151
PI3K-Akt signaling pathway
pyu04152
AMPK signaling pathway
pyu04211
Longevity regulating pathway
pyu04213
Longevity regulating pathway - multiple species
pyu04510
Focal adhesion
pyu04520
Adherens junction
pyu04550
Signaling pathways regulating pluripotency of stem cells
pyu04730
Long-term depression
pyu04913
Ovarian steroidogenesis
pyu04914
Progesterone-mediated oocyte maturation
pyu05200
Pathways in cancer
pyu05202
Transcriptional misregulation in cancer
pyu05205
Proteoglycans in cancer
pyu05214
Glioma
pyu05215
Prostate cancer
pyu05218
Melanoma
pyu05224
Breast cancer
pyu05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121042474 (IGF1R)
04014 Ras signaling pathway
121042474 (IGF1R)
04015 Rap1 signaling pathway
121042474 (IGF1R)
04066 HIF-1 signaling pathway
121042474 (IGF1R)
04068 FoxO signaling pathway
121042474 (IGF1R)
04151 PI3K-Akt signaling pathway
121042474 (IGF1R)
04152 AMPK signaling pathway
121042474 (IGF1R)
04150 mTOR signaling pathway
121042474 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
121042474 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
121042474 (IGF1R)
04140 Autophagy - animal
121042474 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
121042474 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
121042474 (IGF1R)
04520 Adherens junction
121042474 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
121042474 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
121042474 (IGF1R)
04914 Progesterone-mediated oocyte maturation
121042474 (IGF1R)
09156 Nervous system
04730 Long-term depression
121042474 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
121042474 (IGF1R)
04213 Longevity regulating pathway - multiple species
121042474 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121042474 (IGF1R)
05202 Transcriptional misregulation in cancer
121042474 (IGF1R)
05205 Proteoglycans in cancer
121042474 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
121042474 (IGF1R)
05214 Glioma
121042474 (IGF1R)
05218 Melanoma
121042474 (IGF1R)
05215 Prostate cancer
121042474 (IGF1R)
05224 Breast cancer
121042474 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121042474 (IGF1R)
01522 Endocrine resistance
121042474 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121042474 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pyu04090
]
121042474 (IGF1R)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
121042474 (IGF1R)
Protein kinases [BR:
pyu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
121042474 (IGF1R)
CD molecules [BR:
pyu04090
]
Proteins
121042474 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
121042474
NCBI-ProteinID:
XP_040349705
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTDSNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWGHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCSGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNITVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPEDMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgatatccgt
aacgactatcagcagctgaagcgcctggagaactgcacggtgattgagggctacctccac
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgctgctgttccgcgtggccggcctcgagagcctcggggacctcttc
ccgaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattacccggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccacggtggactggtccctaatc
ctggatgcggtgtctaataactacatcgtgggaaacaagcccccaaaggaatgcggggac
ctgtgtccggggacgatggaggagaagcccttgtgcgagaagacgaccatcaacaatgaa
tacaactaccgctgctggacgaccaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcacagacagcaacgagtgctgtcaccccgagtgcctgggcagctgcagc
gcgccggacaacgacacggcctgtgtggcctgcaggcattactactacgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgctttgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgat
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacgggagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgcgaggaggagaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatctg
ctcattaatatccgccgaggcaataacattgcttcggagctggagaacttcatgggactc
atcgaggtggtgacaggctatgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctcaaaaaccttcgccagatcttaggagaggagcagctggaggggaactactctttc
tatgtcctcgacaaccagaacctgcagcagctctgggactggggccaccgcaatctgacc
atcaaagctgggaagatgtactttgctttcaaccccaagttgtgcgtctccgaaatttac
cgcatggaggaggtgaccgggactaaggggcgccagagcaaaggggacatcaatacgagg
aacaatggagagcgagcctcctgtgaaagtgacgtcctgcacttcacctctacgaccacg
tggaagaaccgcatcatcataacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaggcaccttttaaaaacgtcacggagtatgatggc
caggatgcctgtggctccaacagctggaacatggtagacgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcacggactaaagccttggacgcagtatgccgtttac
gtcaaggcagtgaccctcaccatggtggagaatgaccacatccgcggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttcggca
tcaaactcctcttctcagctcatcgtgaagtggaacccgccgtccctgcccaacggcaac
ctgagttactacatcgtgcggtggcagcggcagccccaggacagctacctttaccgccac
aactactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccattgacgtc
gaggaggtgaccgagaaccccaagaccgaagtgtgcagcggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggcggagaaggaggaggctgagtaccgcaaa
gtcttcgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcacacaagtcaccaacaccaccatgtccagccgaagcaggaacatcacggtggca
gacacctataatatcacagaccccgaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtgatctctaacctccggcctttcactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagacgacattcctgggccggtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ctgattctaatgtatgaaataaaatatggatcacaaatcgaggatcagcgggaatgtgta
tccagacaggagtaccggaagtatggaggcgccaagcttaaccggctcaaccccgggaac
tatacggcccggatccaggccacctctctctctgggaatgggtcgtggacggatcccgtg
ttcttctacgtccccgccaaaataacatatgaaaatttcatccacctgatcatcgctctg
cctgttgccgtcctgctgatagtggggggactggttatcatgttgtacgtcttccacaga
aaaagaaataacagcaggctggggaatggagtgctgtatgcttcggtgaacccagagtac
ttcagtgccgcagatgtgtatgtacctgatgagtgggaggttgctcgggagaaaatcacc
atgagccgagagctggggcagggctcgtttgggatggtctacgaaggagttgccaaaggc
gtggttaaagatgagcccgaaaccagggtggccatcaaaacggtgaacgaggccgcgagc
atgcgtgaaaggattgaatttctcaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtggtgtcccaaggccagccgacgctggtcatcatggaa
ctgatgacgcggggcgatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggagagattgca
gacggcatggcatacctcaacgccaacaagtttgtccacagggaccttgctgcccggaac
tgcatggtggctgaagatttcacagtcaaaattggagatttcggtatgacgagagatatc
tacgagacagactattaccggaaaggagggaaggggctgctgcctgtgcgctggatgtca
cccgagtccctcaaggatggggtcttcaccactcactctgacgtctggtccttcggggtc
gttctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaacgagcaa
gtgcttcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggaacccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggatctggagccggaggacatg
gagagcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggccccggcgtgctggttctccgagccagcttc
gacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
