| Entry |
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| Symbol |
SLC8A1
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| Name |
(RefSeq) sodium/calcium exchanger 1 isoform X1
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| KO |
| K05849 | solute carrier family 8 (sodium/calcium exchanger) |
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| Organism |
pyu Puma yagouaroundi (jaguarundi)
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| Pathway |
| pyu04261 | Adrenergic signaling in cardiomyocytes |
| pyu04961 | Endocrine and other factor-regulated calcium reabsorption |
| pyu04974 | Protein digestion and absorption |
| pyu05412 | Arrhythmogenic right ventricular cardiomyopathy |
|
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| Brite |
KEGG Orthology (KO) [BR:pyu00001]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
121044375 (SLC8A1)
04020 Calcium signaling pathway
121044375 (SLC8A1)
04022 cGMP-PKG signaling pathway
121044375 (SLC8A1)
09150 Organismal Systems
09153 Circulatory system
04260 Cardiac muscle contraction
121044375 (SLC8A1)
04261 Adrenergic signaling in cardiomyocytes
121044375 (SLC8A1)
09154 Digestive system
04974 Protein digestion and absorption
121044375 (SLC8A1)
04978 Mineral absorption
121044375 (SLC8A1)
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
121044375 (SLC8A1)
09157 Sensory system
04740 Olfactory transduction
121044375 (SLC8A1)
09160 Human Diseases
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
121044375 (SLC8A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
121044375 (SLC8A1)
05414 Dilated cardiomyopathy
121044375 (SLC8A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:pyu02000]
121044375 (SLC8A1)
00536 Glycosaminoglycan binding proteins [BR:pyu00536]
121044375 (SLC8A1)
Transporters [BR:pyu02000]
Solute carrier family (SLC)
SLC8: Na+/Ca2+ exchanger
121044375 (SLC8A1)
Glycosaminoglycan binding proteins [BR:pyu00536]
Heparan sulfate / Heparin
Others
121044375 (SLC8A1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1004 aa
MLRCWASRRPHPPGSAPRSSLLLVGTVGSLPLYNMLRLRLSPTFSVGFHLLAFVALLFSH
VDLISADTEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMF
LGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEI
LLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAA
WSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAG
KQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARI
LKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARK
AVSMHEVNTEVAENDPVSKIFFEQGTYQCLENCGTVALTILRRGGDLTNTVFVDFRTEDG
TANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGI
LEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGN
VIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP
RLVEMSEKKALLLNELGGFTITGKYLYGQPVFRKVHAREHPIPSTVITIAEECDDKQPLT
SKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFI
EAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSIL
MIGILTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGN
VTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRR
RPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF |
|---|
| NT seq |
3015 nt +upstreamnt +downstreamnt
atgctgcgctgctgggcatccaggcgtccccacccaccgggctctgctccgaggtcatcc
ctcctcctggttgggacagttggaagcctaccattgtacaacatgctgcgattaagactc
tcacctacattttcagtgggatttcatctgttagccttcgtggcactcttattttcccat
gtggaccttataagtgctgacacagaaatggaaggagaaggcaatgaaactggcgagtgt
accggctcatattactgtaagaagggggtgattttacccatttgggagccccaagaccct
tcctttggagacaaaattgctagagctaccgtgtatttcgtggccatggtctacatgttt
ctcggagtctctatcattgccgaccggttcatgtcctctatagaagtcatcacgtctcaa
gaaaaagaaataaccataaagaaacccaatggagagaccaccaagaccactgtgaggatc
tggaatgagaccgtttcgaacctgaccttgatggccctgggatcttctgctccagagatt
ctcctttcggtaattgaagtgtgtggccacaacttcactgcgggagacctaggtcccagc
accatcgtgggaagtgctgcgttcaatatgttcatcattatcgcgctttgtgtttacgtg
gtcccagatggagagacgaggaagattaagcatttgcgtgtgttctttgtgacagcagcc
tggagcatctttgcctatacttggctttacattattttgtctgtcatctctcctggggtc
gtggaggtgtgggaaggtttgcttactttcttcttctttcccatctgtgttgtgttcgct
tgggtagcagataggaggcttctgttttacaagtatgtctacaagaggtatcgggctggc
aagcagaggggaatgattattgaacatgaaggagacaggccatcttccaagactgaaatt
gaaatggatgggaaagtggtcaattcccacgttgacaatttcttagatggtgccctggtt
ctggaggttgacgagagggaccaagatgatgaagaggccaggcgagaaatggctaggatt
ctgaaggagctcaagcagaaacatccggagaaagaaatagagcaattaatagaattagct
aactaccaagtcctaagtcagcagcaaaaaagtcgagcattttaccgcatccaagctact
cgcctcatgactggagctggcaacattttaaagaggcatgcagctgaccaggcaaggaag
gcagtcagcatgcatgaggtcaacactgaagtggctgaaaatgaccctgttagtaagatc
ttctttgaacaagggacataccagtgtctggagaactgtggtactgtagccctgaccatt
ctccgcagaggtggtgatttgaccaacactgtgtttgttgacttcagaacagaagatggc
acagccaatgctgggtctgattacgaatttaccgaaggaactgtggtctttaagcctggt
gagacccagaaggagatcagagttggcatcattgatgacgatatctttgaggaggatgag
aatttccttgtgcatctgagcaacgttaaggtatcttccgaagcctcagaagacggcatc
ctggaagccaatcatgtttctacactcgcttgcctcggctctccctccactgccactgtg
actatcttcgatgatgaccacgctggcatctttacttttgaggaacctgtgactcatgtg
agcgagagcattggcattatggaggtgaaggtattgagaacatctggagctcgaggaaat
gttatcgttccctataaaaccatcgaagggactgccagaggtggtggggaggactttgag
gacacttgcggagagctcgagttccagaacgacgaaattgtcaaaacaatatcagtcaag
gtaattgatgatgaggagtatgagaaaaacaagaccttcttccttgagattggagagccc
cgcctggtggagatgagtgagaagaaagccctgttactgaatgagcttggtggcttcaca
ataacaggaaaatacctgtacggccagcctgtcttccggaaagttcatgctagagaacat
ccgatcccttctactgtaatcaccattgcagaggaatgtgatgacaagcagccgctgacc
agcaaagaggaagaggagaggcgcattgcagaaatggggcgccccattctgggagaacac
accaagctggaagtgatcattgaagaatcctacgaattcaagagtaccgtggacaaactt
attaagaagacaaacttagcccttgtggttgggacaaacagctggagagagcagtttatc
gaagccatcactgtcagcgctggggaagatgacgacgacgatgaatgtggggaggagaag
ctaccctcctgtttcgattatgtgatgcatttcctgactgtgttctggaaggtcctcttc
gccttcgtcccccctacagaatactggaatggctgggcctgtttcattgtctccatcctc
atgatcggcatactgacagctttcattggagacctggcttcccacttcggatgcaccatt
ggcctgaaagattctgtgactgcggtagtgttcgtcgcgcttggaacttcggtaccagat
acgtttgcaagcaaagtggccgccacccaggaccagtacgcagatgcatccataggtaac
gtcactggcagcaacgcggtgaacgtcttcctgggaatcggcgtggcctggtccatcgct
gccatctaccacgcagccaacggggaacagttcaaagtgtcccctggcacgctagctttc
tctgtcactctcttcaccatttttgctttcatcaatgtgggggtgctgctgtatcggcga
aggccggagatcggaggtgagctgggtgggccccggactgccaagctcctcacatcctgc
ctcttcgtgctcctatggctcttgtacattttcttctcctccctggaggcctactgccac
ataaaaggcttctaa |
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