KEGG   Puma yagouaroundi (jaguarundi): 121044690
Entry
121044690         CDS       T07555                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
pyu  Puma yagouaroundi (jaguarundi)
Pathway
pyu01521  EGFR tyrosine kinase inhibitor resistance
pyu01522  Endocrine resistance
pyu04012  ErbB signaling pathway
pyu04066  HIF-1 signaling pathway
pyu04140  Autophagy - animal
pyu04150  mTOR signaling pathway
pyu04151  PI3K-Akt signaling pathway
pyu04152  AMPK signaling pathway
pyu04211  Longevity regulating pathway
pyu04213  Longevity regulating pathway - multiple species
pyu04350  TGF-beta signaling pathway
pyu04371  Apelin signaling pathway
pyu04666  Fc gamma R-mediated phagocytosis
pyu04714  Thermogenesis
pyu04910  Insulin signaling pathway
pyu04931  Insulin resistance
pyu05163  Human cytomegalovirus infection
pyu05165  Human papillomavirus infection
pyu05170  Human immunodeficiency virus 1 infection
pyu05200  Pathways in cancer
pyu05205  Proteoglycans in cancer
pyu05207  Chemical carcinogenesis - receptor activation
pyu05210  Colorectal cancer
pyu05212  Pancreatic cancer
pyu05221  Acute myeloid leukemia
pyu05224  Breast cancer
pyu05225  Hepatocellular carcinoma
pyu05226  Gastric cancer
pyu05231  Choline metabolism in cancer
pyu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    121044690 (RPS6KB1)
   04066 HIF-1 signaling pathway
    121044690 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    121044690 (RPS6KB1)
   04152 AMPK signaling pathway
    121044690 (RPS6KB1)
   04150 mTOR signaling pathway
    121044690 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    121044690 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    121044690 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    121044690 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    121044690 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    121044690 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121044690 (RPS6KB1)
   05205 Proteoglycans in cancer
    121044690 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    121044690 (RPS6KB1)
   05231 Choline metabolism in cancer
    121044690 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121044690 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    121044690 (RPS6KB1)
   05212 Pancreatic cancer
    121044690 (RPS6KB1)
   05225 Hepatocellular carcinoma
    121044690 (RPS6KB1)
   05226 Gastric cancer
    121044690 (RPS6KB1)
   05221 Acute myeloid leukemia
    121044690 (RPS6KB1)
   05224 Breast cancer
    121044690 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    121044690 (RPS6KB1)
   05163 Human cytomegalovirus infection
    121044690 (RPS6KB1)
   05165 Human papillomavirus infection
    121044690 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    121044690 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121044690 (RPS6KB1)
   01522 Endocrine resistance
    121044690 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pyu01001]
    121044690 (RPS6KB1)
Enzymes [BR:pyu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     121044690 (RPS6KB1)
Protein kinases [BR:pyu01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   121044690 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 121044690
NCBI-ProteinID: XP_040352864
LinkDB
Position
Unknown
AA seq 539 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSSGAYEVQHQGSGRFGVWLYSLVPHMPNPVAASS
SWTAQHPWTTQYPWPVSIYQRNNDKLLPSPVRERDVCLFHPFCHFQQLVSRTRKARREK
NT seq 1620 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatttcggaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacggaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgctaaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaggaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagttcaagctcatccattcttcaggcatattaattgggaagaactg
ctggctaggaaggtggaacccccttttaaacctctgttgcaatctgaggaggatgtgagt
cagtttgattcaaagtttacacgtcagacacctgttgacagcccagatgactcaactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgttgctccatctgtacttgaa
agtgtgaaagaaaaattttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccgcgaacacctgtcagttcaggagcctacgaagtccagcatcaaggttctggcaga
tttggtgtctggctttactccttggtgcctcatatgcctaaccctgttgcagcatctagt
tcttggacggcacagcatccttggacgacacagtatccttggccagttagcatttaccag
agaaataatgacaagctacttccatccccagttagagaaagagatgtttgcctttttcac
cctttctgccacttccagcagctggtgagtaggaccagaaaggcgaggagagagaagtaa

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