Herpailurus yagouaroundi (jaguarundi): 121044914
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Entry
121044914 CDS
T07555
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
pyu
Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu01521
EGFR tyrosine kinase inhibitor resistance
pyu01522
Endocrine resistance
pyu01524
Platinum drug resistance
pyu04010
MAPK signaling pathway
pyu04012
ErbB signaling pathway
pyu04020
Calcium signaling pathway
pyu04066
HIF-1 signaling pathway
pyu04151
PI3K-Akt signaling pathway
pyu04510
Focal adhesion
pyu04518
Integrin signaling
pyu04520
Adherens junction
pyu04530
Tight junction
pyu05200
Pathways in cancer
pyu05205
Proteoglycans in cancer
pyu05206
MicroRNAs in cancer
pyu05212
Pancreatic cancer
pyu05213
Endometrial cancer
pyu05215
Prostate cancer
pyu05219
Bladder cancer
pyu05223
Non-small cell lung cancer
pyu05224
Breast cancer
pyu05226
Gastric cancer
pyu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121044914 (ERBB2)
04012 ErbB signaling pathway
121044914 (ERBB2)
04066 HIF-1 signaling pathway
121044914 (ERBB2)
04020 Calcium signaling pathway
121044914 (ERBB2)
04151 PI3K-Akt signaling pathway
121044914 (ERBB2)
09133 Signaling molecules and interaction
04518 Integrin signaling
121044914 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
121044914 (ERBB2)
04520 Adherens junction
121044914 (ERBB2)
04530 Tight junction
121044914 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121044914 (ERBB2)
05206 MicroRNAs in cancer
121044914 (ERBB2)
05205 Proteoglycans in cancer
121044914 (ERBB2)
05230 Central carbon metabolism in cancer
121044914 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
121044914 (ERBB2)
05226 Gastric cancer
121044914 (ERBB2)
05219 Bladder cancer
121044914 (ERBB2)
05215 Prostate cancer
121044914 (ERBB2)
05213 Endometrial cancer
121044914 (ERBB2)
05224 Breast cancer
121044914 (ERBB2)
05223 Non-small cell lung cancer
121044914 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121044914 (ERBB2)
01524 Platinum drug resistance
121044914 (ERBB2)
01522 Endocrine resistance
121044914 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121044914 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pyu04147
]
121044914 (ERBB2)
04090 CD molecules [BR:
pyu04090
]
121044914 (ERBB2)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
121044914 (ERBB2)
Protein kinases [BR:
pyu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
121044914 (ERBB2)
Exosome [BR:
pyu04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
121044914 (ERBB2)
CD molecules [BR:
pyu04090
]
Proteins
121044914 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
121044914
NCBI-ProteinID:
XP_040353334
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGATGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLHANASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLDSGTPATGAALGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACQPCSPACKDSHCWGASSGDCQSLTRTVCAGGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFVGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTV
PWDQLFRNPHQALLHSANRPEDECAGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRATPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
acgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaagtggtacagggcaacctg
gagctcacctacctgcatgccaatgccagcctctccttcctgcaggatatccaggaggtg
caaggctatgtgctcattgcccacaaccaagtgagacaggtcccactgcagaggctacga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaacgga
gacccactggacagtggcacccctgctacaggggctgccctaggagggctgcgggagctg
cagctccgaagcctcacagagatcctgaagggaggggtcctcattcagcggaacccgcag
ctctgccaccaggacacgattctgtggaaggacatcttccataagaacaaccagctggcc
ctcatgctgatagacaccaaccgctctcgggcctgccaaccctgttctccagcttgtaaa
gactcccactgctggggagcaagttccggggactgtcagagcttgactcgaactgtctgt
gctggtggctgtgcccgctgcaagggcccgcagcccaccgactgctgccacgagcagtgt
gctgctggctgcacgggccccaagcattctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgaa
tccatgcccaaccctgagggccgttataccttcggtgccagctgtgtgactgcctgtccc
tacaactacctgtctacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggatggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctaggcatggagcacctgcgggaggcgagggcagtcaccagtgccaac
atccaagaatttgtcggctgcaagaagatctttgggagcctggcgtttctgccagagagc
tttgagggggacccagcctccaacactgcccccctgcagcctgagcagctcagagtgttt
gaggctctggaggagattacaggttacctgtacatctccgcgtggccagacagcttgcct
aacctcagtgtcttccagaacctcagagtgatccggggccgagttctgcatgacggtgct
tactcgctgacccttcaagggctgggcatcagctggctggggctgcgctcgctgcgggag
ctgggcagtgggctggccctcatccaccgcaactcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagcgccaaccggcca
gaggacgagtgcgcgggtgagggcctggcctgctacccgctgtgtgcccatgggcactgc
tggggtccgggacccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggcttccccgggagtacgtgaaggataggttctgt
ctgccatgccacccggagtgtcagccccagaatggctcagtgacctgcttgggctcggaa
gctgaccagtgtgtggcctgtgcccactacaaggaccctcctttctgtgtggctcgctgc
cccagtggggtgaaacctgacctctccttcatgcccatctggaagttcgcagatgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgtgcggacctggacgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgctgctgtggtgggc
attctgctggtcgtggttgtggggctggtccttggcatcctaatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacggagctggtggagcccctg
acgcctagtggagccatgcccaaccaggctcagatgcgaatcctgaaagaaacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcactgtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaatacatct
cccaaagccaacaaagaaatcttggacgaagcgtatgtgatggctggcgtgggctcccca
tatgtgtctcgccttctgggcatctgtctgacatccaccgtgcagttggtgacacagctt
atgccttatggctgcctcttagaccatgtccgagaacaccgtgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccacgtcaag
attacagattttgggctggctcggctgctggacattgacgagacagagtaccatgccgat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
catcagagtgacgtgtggagctacggtgtgactgtatgggaactgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcggccacgtttccgggagttggtggccgaattctcccggatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccagccagtcccttg
gacagcactttctaccgttcactgctggaggatgaggacatgggagacctggtggacgct
gaggagtacctggtaccccagcagggtttcttctgcccagaccctgccccaggcgccggg
ggcacagcccaccgcagacaccgcagctcatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctccgaggaagagcctcccaagtctccattggcaccctcagaaggg
gctggctctgatgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
ctttccccacaggaccccagccctctacagcggtacagtgaggatcctaccgtaccccta
ccccctgagactgatggctacgttgcccccctgacctgcagtccccagcctgaatatgtg
aaccagccagaggtttggccaaagcccccatcgcccttagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctttccccc
ggcaagaatggggttgtcaaagacgtttttgcctttgggggtgctgtggagaaccccgag
tacttggcaccccggggcagggctacccctcagccccaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacacatctgagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccccgaatacctgggcctggatgtgccagtg
tga
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