Puma yagouaroundi (jaguarundi): 121044941 Help Entry 121044941         CDS       T07555                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:pyu00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     121044941 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:pyu03032]     121044941 (TOP2A)    03036 Chromosome and associated proteins [BR:pyu03036]     121044941 (TOP2A) Enzymes [BR:pyu01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      121044941 (TOP2A) DNA replication proteins [BR:pyu03032]  Eukaryotic type   DNA Topoisomerases    121044941 (TOP2A) Chromosome and associated proteins [BR:pyu03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     121044941 (TOP2A)   Centrosome formation proteins    Centriole proteins     121044941 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  121044941 NCBI-ProteinID:  XP_040353388 LinkDB All DBs Position Unknown AA seq 1534 aa AA seqDB search MEVSPLQPVNENMLINKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVEVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCHLSEKFIKAAIGCGIVESILNWVKFKAQ VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFRGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKGDSVKDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA KGKKIQMAEVLPSPCGKRVIPRVTIEMKAEAEKKIKKKIKSENTEGSPQEDGMELEGLKQ RLEKKQKREPGTKTKKQTTLPFKPVKKGKKRNPWSDSESDMSSNESDFDVPPREIEPRRA ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSDVSPVKTKTSPPVPTNKELKPQKSATSVM DLDAGGAKDSVPPSLDSPAADFSAETEVINPVSKKKVAVKKTAAKSQSSTSTAGAKKRAA PKGTKKEPGLNSDVSQKPDPPKTKNRRKRKPSTSDDSDSNFEKMISKTVTSKKSKGESED FHLDLDSAVVPRAKSGRAKKPIKYLEESDEDDLF NT seq 4605 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccactgcagcctgtaaatgaaaatatgctaatcaacaaaacaaagaaa aatgaagatgccaagaaaagactgtctattgaaaggatctatcaaaagaaaacccaactg gaacatattttgctccgcccagacacctatattggctccgtggaattagtgacccagcaa atgtgggtttacgatgaagatattggcattaactatagggaagtcacctttgtccctggg ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacgtggatggataacatgggaagg gctggtgagatggaactcaagcccttcaatggggaagattatacatgtattaccttccag cctgatttgtccaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtc agaagagcatatgatattgccggatccactaaagatgtcaaagtgtttctcaatggaaat aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat gaaactggcaatccgttgaaaattatccatgaacaagtaaaccccaggtgggaagtatgc ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattatatagctgatcagattgtgactaaacttgttgaggtt gttaaaaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg tggatttttgtgaatgccttaattgaaaacccaacctttgattctcagacaaaagagaac atgactttacaagtcaagagctttggatcaacctgccatttaagtgaaaaattcatcaaa gctgcaattggttgtggtattgtagaaagtatactaaactgggtgaagtttaaggcccaa gtccagttaaacaagaagtgttcagctgtaaaacataacaggatcaagggaattcccaaa ctcgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacacttatcctgact gagggagactcagctaaaactttggctgtttcgggccttggtgtggttgggagagacaaa tatggggttttcccgcttagaggaaaaatactcaatgttcgagaagcttctcataaacag atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtataagaaa aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcttgctgattaattttatccatcacaac tggccctctcttctgcggcaccgttttctggaagaatttatcactcctattgtaaaggtg tctaaaaacaagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagt tctacaccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcacgagcaca tcaaaagaggctaaggaatactttgcagatatgaaaagacatcgtattcaattcaaatat tccggtcctgaagatgatgccgccatcagcctggcctttagcaagaaacagatagatgat cgaaaggaatggttaactcatttcatggaggacagaaggcaacggaagttacttggcctt cctgaggattacttgtatgggcaaactaccacatatctgacatacaatgacttcataaac aaggaacttatcctgttctcaaattctgataacgagagatctattccatctatggtggat ggtttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgacaagcga gaggtgaaggttgctcagttagctggatcagtggctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcaacccattggtcagtttggtaccaggctgcatggtggtaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcatacattaaagtttttatatgatgacaatcaacgtgttgaacctgaatgg tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg tcctgcaaaatcccgaactttgatattcgtgaagttgtaaataatatcaggcgtctgatg gatggagaagaacctttgccaatgcttccgagttacaagaacttcaggggtacgattgaa gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc attgaaatctcagaacttcccatcagaacatggacccagacatataaagaacaggttcta gaacccatgttgaatggcactgagaagacaccacctctcataaccgattatagggaatac catacagacaccactgtgaagtttgttgtgaagatgactgaagagaaattggcagaggca gagagagtgggactgcacaaagtcttcaaactccaaactagtctcacatgcaactctatg gtgctttttgaccatgtaggatgtttaaagaaatatgacacagtgttggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagaatggctactaggaatg cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaataatcattgaaaataagccaaagaaggaattaattaaagttctgattcagagg ggttatgattctgatcctgtgaaggcttggaaagaagcccagcaaaaggtaccagatgaa gaagaaaatgaagagagtgacaatgaaaatgaagctgaaaagggtgactctgtaaaagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggaaaag aaggatgaactgtgcaagctgagaaatgaaaaagaacaagagctagaaacattaaagaga aagagtccatcagatttgtggaaagaagacctagctgcttttattgaagagctggaggct gttgaaacaaaggaaaaacaagaagaacaaataggactccctgggaaagggggtaaagca aaggggaaaaaaatacagatggctgaagttttgccttcgccatgtgggaaaagagtcatc ccccgagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag agtgaaaacactgaagggagccctcaagaggatggtatggaactagaaggtctgaaacaa aggttggagaagaaacagaaaagagaaccaggtaccaagacaaagaagcaaactacgttg ccatttaaaccagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat atgagcagtaatgaaagtgactttgatgttcccccacgagagatagagccacggagagcg gcaacaaaaaccaaatttacagtggatttggattcagatgatgatttctcagattttgat gaaaaaactcaagatgaggattttgtcccatcagatgttagcccagttaagaccaaaact tccccaccagtacctactaacaaagaactgaagccacagaagagtgccacatcagtaatg gaccttgatgctggtggtgccaaggacagtgtaccaccttctctagattctccggctgct gatttctcagctgaaactgaagtcataaaccctgtttctaaaaagaaggtagcggtgaag aagacagcagcaaaaagtcagtcttccacctccactgcaggtgccaaaaaaagggctgca ccaaaaggaaccaaaaaggagccaggcttgaattctgatgtctctcaaaagcctgatcct cccaaaaccaaaaatcgccgcaaaaggaagccatccacttctgatgattctgactctaat tttgagaaaatgatttctaagacagtcacaagcaagaaatccaagggggagagtgaggat ttccatctggacttagactcagctgtggttcctcgggccaaatctggacgggcaaagaaa cctataaagtacctcgaagaatcagatgaagatgatctgttctaa

DBGET integrated database retrieval system