| Entry |
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| Symbol |
CAMK2A
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| Name |
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
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| KO |
| K04515 | calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] |
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| Organism |
pyu Puma yagouaroundi (jaguarundi)
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| Pathway |
| pyu04261 | Adrenergic signaling in cardiomyocytes |
| pyu04750 | Inflammatory mediator regulation of TRP channels |
| pyu04925 | Aldosterone synthesis and secretion |
| pyu05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:pyu00001]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
121045049 (CAMK2A)
04310 Wnt signaling pathway
121045049 (CAMK2A)
04066 HIF-1 signaling pathway
121045049 (CAMK2A)
04020 Calcium signaling pathway
121045049 (CAMK2A)
04024 cAMP signaling pathway
121045049 (CAMK2A)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
121045049 (CAMK2A)
09143 Cell growth and death
04114 Oocyte meiosis
121045049 (CAMK2A)
04217 Necroptosis
121045049 (CAMK2A)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
121045049 (CAMK2A)
04922 Glucagon signaling pathway
121045049 (CAMK2A)
04912 GnRH signaling pathway
121045049 (CAMK2A)
04921 Oxytocin signaling pathway
121045049 (CAMK2A)
04916 Melanogenesis
121045049 (CAMK2A)
04925 Aldosterone synthesis and secretion
121045049 (CAMK2A)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
121045049 (CAMK2A)
09154 Digestive system
04971 Gastric acid secretion
121045049 (CAMK2A)
09156 Nervous system
04725 Cholinergic synapse
121045049 (CAMK2A)
04728 Dopaminergic synapse
121045049 (CAMK2A)
04720 Long-term potentiation
121045049 (CAMK2A)
04722 Neurotrophin signaling pathway
121045049 (CAMK2A)
09157 Sensory system
04740 Olfactory transduction
121045049 (CAMK2A)
04750 Inflammatory mediator regulation of TRP channels
121045049 (CAMK2A)
09158 Development and regeneration
04360 Axon guidance
121045049 (CAMK2A)
09159 Environmental adaptation
04713 Circadian entrainment
121045049 (CAMK2A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121045049 (CAMK2A)
05205 Proteoglycans in cancer
121045049 (CAMK2A)
09162 Cancer: specific types
05214 Glioma
121045049 (CAMK2A)
09171 Infectious disease: bacterial
05152 Tuberculosis
121045049 (CAMK2A)
09164 Neurodegenerative disease
05012 Parkinson disease
121045049 (CAMK2A)
05022 Pathways of neurodegeneration - multiple diseases
121045049 (CAMK2A)
09165 Substance dependence
05031 Amphetamine addiction
121045049 (CAMK2A)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
121045049 (CAMK2A)
05415 Diabetic cardiomyopathy
121045049 (CAMK2A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
121045049 (CAMK2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:pyu01001]
121045049 (CAMK2A)
Enzymes [BR:pyu01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
121045049 (CAMK2A)
Protein kinases [BR:pyu01001]
Serine/threonine kinases: CAMK group
CAMK2 family
121045049 (CAMK2A)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
571 aa
MANDGRAGGWKGKFQAERTTRVKAPSPRERVVQGGSGGVPVSGSIPAGAPWEGQGWGRGR
GLPWGAVPGLLVVALGGTSVESPREPRPRERKGLLRHCNLVSPPSAASRCLPGGPRAPAR
EASFSRRGPGAALADHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELF
EDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFG
LAIEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQ
HRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVA
SCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQL
MESSESTNTTIEDEDTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGN
LVEGLDFHRFYFENLWSRNSKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTA
QSEETRVWHRRDGKWQIVHFHRSGAPSVLPH |
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| NT seq |
1716 nt +upstreamnt +downstreamnt
atggccaatgatggccgggcgggaggttggaagggaaagttccaagctgagagaaccaca
cgggtgaaggccccaagcccaagggagagggttgtgcagggtgggtctggaggagtgcct
gtcagtggttcaatcccagctggagccccgtgggaggggcaaggctgggggcggggcagg
ggcctgccctggggggccgttccggggctcctggttgtggctctgggaggcacctcagtt
gagagcccccgggaaccaaggcccagagagaggaagggacttctgaggcactgcaacctg
gtctctcccccttctgctgcatcccgctgccttcctggaggacccagggcccctgccaga
gaggcgagcttctccaggcggggcccaggggctgccctggcagaccatcagaagctggag
cgtgaagcccgcatctgccgcctgttgaagcaccccaacatcgtccggctccacgacagc
atctctgaggagggacaccattacctgatcttcgacctggttactggtggggagctgttt
gaggacatcgtggcccgggagtattacagtgaggctgatgccagtcactgtatccagcag
atcctggaggccgtgctgcactgccaccagatgggtgtggtgcaccgggacctgaagccg
gagaatctgctgttggcttccaagctcaagggcgccgcggtgaagctggcggactttggc
ctggccatagaggtggaaggggagcagcaggcatggttcgggttcgcagggacgcctgga
tacctctccccggaagtgctgcggaaggacccgtatgggaagcctgtggacctgtgggcc
tgtggggtcattctgtacatcctgctggttgggtatccgccattctgggatgaggaccag
caccgcctgtatcagcaaatcaaagccggcgcctatgatttcccgtcaccagaatgggac
actgtcaccccggaagccaaggatctgatcaataagatgctgaccatcaacccatccaaa
cgcatcacggccgccgaggccctcaagcacccttggatctcgcatcggtccactgtggcc
tcctgcatgcacagacaggagaccgtggactgcctgaagaagttcaacgccaggagaaaa
ctgaagggagccatccttaccacaatgctggctaccaggaacttctctggagggaagagc
ggaggaaacaagaagaatgatggtgtgaagaaaagaaagtccagttccagcgttcagtta
atggaatcttcagagagtaccaataccaccattgaggatgaagacaccaaagtgcggaaa
caggagattataaaagtgacagagcagctgatcgaagccataagcaatggagattttgag
tcctacacgaagatgtgtgaccctgggatgacagccttcgaacctgaggccctggggaac
ctggtcgagggcctggacttccatcgattctattttgaaaacttgtggtctcggaacagc
aagcccgtgcacaccaccatcctgaacccccacatccatctgatgggtgacgagtcggcc
tgcatcgcctacatccgcatcacgcagtacctggatgcgggtggcatcccccgcacggcc
cagtcggaggagacccgtgtctggcaccgccgggatggcaaatggcagatcgtccacttc
cacagatctggggcgccctccgtcctgccccattga |
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