Providencia zhejiangensis: ACE2AM_03215
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Entry
ACE2AM_03215 CDS
T10958
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pzn Providencia zhejiangensis
Pathway
pzn00260
Glycine, serine and threonine metabolism
pzn00261
Monobactam biosynthesis
pzn00270
Cysteine and methionine metabolism
pzn00300
Lysine biosynthesis
pzn01100
Metabolic pathways
pzn01110
Biosynthesis of secondary metabolites
pzn01120
Microbial metabolism in diverse environments
pzn01230
Biosynthesis of amino acids
Module
pzn_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pzn_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pzn_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
pzn_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
pzn00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ACE2AM_03215 (thrA)
00270 Cysteine and methionine metabolism
ACE2AM_03215 (thrA)
00300 Lysine biosynthesis
ACE2AM_03215 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ACE2AM_03215 (thrA)
Enzymes [BR:
pzn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ACE2AM_03215 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ACE2AM_03215 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF2652
Motif
Other DBs
NCBI-ProteinID:
XGY78643
LinkDB
All DBs
Position
751867..754326
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANDERVLNVADIAESKLADGQVALVLSAPAKITNHLVAMIDKTVAGQDV
ITHVNDAEMIFANLLKGLKEKQPGFDYDRLKKLTEQEFAQIKQVLHGITLLGQCPDSINA
SIICRGEKLSIAIMESVLKARGHKVTVINPVERLLAVGHYLESTVDINESTKRIAELNIP
KDHFVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRAACCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTTNPSAPGTLIGDGQT
DESTPVKGITNLNNMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLITQSSSEYSISF
CVPQGELVRARAALEEEFYLELKDGVLDPLDVMEQLAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANEAATTAVRLCHQMLFNAEQVIEAFIIGVGGVGNAL
IEQIHRQQQWLKQKHIDLRVCGIANSRAMLTNMQGISLDNWKEELAQATEPFSLSRLIRL
EREYHFLNPVIIDCTSNQEIAEQYVNFLKDGFNVVTPNKKANTLSMDYYRQLRSACEVSK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVHFSGILSGSLSFIFGKLDEGMSLSEATTLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYQLELDDIEIDAVLPAEFDSSGSVAEFMA
RLPQLDQQFAERIKAAEAEEKVLRYVGLIEEGRCQVKIVAVDGNDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADMLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgcttaaatttggcggtacttcggttgcaaatgacgaacgagtacttaatgtt
gctgacatcgctgagagtaaattggccgatgggcaggtggctttggtgttatccgcacca
gcaaaaatcactaaccatttggtcgcaatgattgataaaacggttgcaggtcaggatgtc
atcacgcatgtgaatgatgcagaaatgatttttgcaaacttactaaaaggattgaaagaa
aaacaacccggttttgattacgacagactgaaaaaactcaccgaacaagaatttgcacaa
atcaaacaagtactgcatggtattactcttctaggccaatgccctgatagcattaatgct
tccatcatttgtcgtggtgaaaaactctccattgctatcatggaatctgtgttaaaagca
cgcggacacaaagtgacagtgattaaccctgtcgaacgtttattggcagttggccattac
cttgaatcaacagttgatatcaatgaatcaactaagcgtattgcagaattaaatatcccg
aaagaccactttgtattgatggcgggttttaccgcgggtaatgataaaggcgaactggtg
gtattaggacgcaatggttctgattattctgccgctgttttagcggcttgtttacgggcg
gcctgttgtgagatctggaccgatgtggatggggtgtatacctgtgaccctcgtttagtg
cctgatgcgcgtttattaaaagggatgtcttaccaagaagcaatggaactgtcctacttt
ggtgcaaaagttcttcacccacgcaccatcgcgccaatcgcacaattccaaattccttgc
ctgattaaaaataccactaacccaagtgctccggggactttgattggcgatggccaaacg
gatgaaagtacaccagttaaagggatcacgaatcttaataacatggcaatgatcaacgtt
tcgggtcctggcatgaaagggatggttggcatggcagctcgtattttctcagtcatgtcg
cgtaaagggatctcggtggtcttgattactcagtcatcatccgaatacagcattagtttc
tgtgtgccacaaggtgaattagtgcgagcacgcgcagcactggaagaagagttctattta
gaattaaaagacggtgtcttggatcctcttgatgtcatggagcagctggcgattatttct
gtagtgggagatgggatgcgtacccttaaagggatatcagcacgtttcttttcagcttta
acacgcggaaatataaatattgttgcgattgcgcaaggttcatctgaacgctccatttca
gcagtcatcgcgaatgaggcggcaacaacggcagttcgtttatgccatcaaatgctattt
aatgcagagcaggtgatagaagcctttatcattggggtagggggggttggaaatgcattg
attgaacagatccatcgccaacaacaatggttaaagcaaaaacatattgatttacgtgtg
tgcggaattgctaactcaagagccatgctaaccaatatgcaaggcatctctcttgataat
tggaaagaagaacttgcacaagcgacagaaccctttagcttaagtcgtttgatcagactt
gaacgtgaatatcactttctcaatcctgtgattatcgattgtacctctaaccaagagatt
gccgagcagtatgtgaatttcttaaaagatggttttaacgtggtcacgcctaataaaaaa
gctaacacgttatcgatggattattaccgccaactacgttcagcgtgtgaagtatcaaaa
cgtaagttcctttatgacactaacgttggtgcaggtttgccggtgattgaaaacttacag
aatcttctgaatgcgggtgatgagctggtgcactttagtggaattctctctggctcacta
tcctttatctttggtaagttagatgaaggtatgtctctgtctgaggcgacaacattagcg
aaagagaaaggatttactgagcctgacccacgtgatgacttatccggtatggatgttgct
cgtaaactgttgatccttgctcgtgaagcgggctatcaattagagttagacgatattgaa
attgatgcggtattacctgctgagtttgatagcagtggcagtgttgctgaatttatggct
cgtttaccacagctcgaccaacaatttgcagaacgtataaaagccgcagaagcggaagaa
aaagtgttacgctatgttgggttgatagaggaaggacgttgccaagtaaaaattgttgcc
gttgatggcaatgatccactctttaaagtcaagaatggcgaaaacgcattggctttctat
acacgctattaccaaccaatacctttagttctaagaggctatggtgcaggtaatgatgtt
accgctgccggcgtatttgcagatatgttgcgtaccctatcatggaaattgggagtctga
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