Rothia aeria: RA11412_1394
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Entry
RA11412_1394 CDS
T05268
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
raj
Rothia aeria
Pathway
raj00300
Lysine biosynthesis
raj00550
Peptidoglycan biosynthesis
raj01100
Metabolic pathways
raj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
raj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RA11412_1394
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RA11412_1394
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RA11412_1394
Enzymes [BR:
raj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RA11412_1394
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAV87693
UniProt:
A0A2Z5QZA4
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Position
1284585..1286201
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AA seq
538 aa
AA seq
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MIKLSAAEIIQATGGAALGLQDPETVFCTFATTDSREVVPGTLFIAKPGESTDGHRFVAA
AFNSGASLALVERPVTAEPSGELYPAVQVDDAVLAMGRLAAYAIEKMRSLGPVEVIGITG
SAGKTTTKDLLAAIFGAEGATVAPVGSYNGEVGVPLTVFRADETTRYLVIEMGADHVGNI
EYLANIVQPDYGVILKVGTAHAGEFGGVDNIERTKGELAEGIRAGGALALNADDERVLRM
AARACVPVTYFGVGDKPQYERYVAALNLSTNDAGCPEFTLRLPNGQEHLVSSQLIGEHHV
HNLLAAATIAYNAGIAGDRIAHALNTSGAVSKWRMARTDRSDGVSIINDAYNANPESMSA
ALRTLAQLGRGSEPRRTWAVLGAMLELGESSVEEHDHIGRLAVRLNISKLIAVGDTAKPI
YNAAHLEGSWGNEATWVQTPQQALSVLRAELRPGDIVLFKSSNGAKLGQLGDEVAFSSDR
FGSGSEPAPTWLSAGDFVEVTDLTGSVAPTASEPATTSSPVATTASASTTFTGQEGTR
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
atgattaaactaagtgccgccgagattatccaggcgaccggaggtgccgcgctcgggctt
caagaccccgagacggtcttctgtaccttcgccactactgattcacgggaagtagtcccc
ggtaccctttttattgcgaaaccgggagaaagtaccgacgggcaccgttttgttgccgcg
gcttttaactctggtgcttccttagcccttgtggagcggcccgttaccgctgagccttca
ggtgagctgtatcctgccgtgcaggtggatgatgcggtactggcgatggggcgcttggcg
gcatacgctatcgagaagatgcgtagtcttggtcccgtggaagtcattgggattactggt
tccgcagggaaaaccaccaccaaagacttgctggcagctatttttggtgccgagggtgct
acggtggctcccgtgggctcctataacggtgaggttggggtgccgctgacggtattccgt
gcggatgaaaccacccggtacttggttattgaaatgggtgccgaccatgtaggcaatatt
gagtacctggcgaatatcgtacagccggactacggggttatcttaaaggtcggtaccgcc
catgcgggcgagttcggcggggtagacaatattgaacgcaccaaaggtgaactggccgaa
ggcatccgcgccggtggggcgctcgccctcaacgctgacgatgagcgtgtgctgcgcatg
gcagcgcgtgcgtgtgttcccgtcacctatttcggggtgggggataagccacagtacgag
cggtatgtggcggccctgaacttgagcacgaatgatgcggggtgcccggaattcactctg
cggctgcccaacgggcaggaacacctggtgtcgtcacaattaattggtgagcatcatgtg
cataacctgctggcggccgcaactattgcgtataacgctggcatcgcgggggacaggata
gctcacgcgctcaataccagcggtgctgtgtctaaatggcgtatggcccgcaccgaccgc
tctgatggggtgagcatcattaacgatgcgtacaacgcgaacccggagtcaatgtcggct
gcgctacgaactctggcgcagctgggccgcggcagcgagccgcgccgcacctgggccgtg
ctgggggcgatgctggaactgggagaaagcagcgtcgaagagcacgaccatattgggcgg
cttgcagtgcggctcaatatttctaagctaatcgccgtgggagacactgccaaaccaatc
tacaatgccgcgcacctggaaggttcctggggtaatgaggccacctgggtacagaccccg
cagcaggcattgtcggtgctacgcgctgagctgcgccccggcgacattgtgctgtttaaa
tcctccaacggcgccaaacttgggcagttgggagatgaggtggcattcagcagtgaccgg
tttgggtccggctctgagcctgctcctacctggttgagcgctggcgactttgttgaagtg
accgatttgacgggttctgtcgcccccacggcgagtgagcctgcaaccacctccagcccg
gtggccactacggcctccgcttccaccacattcaccggccaggaaggcacacgctag
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