Rathayibacter sp. VKM Ac-2759: GSU68_07770
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Entry
GSU68_07770 CDS
T10520
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rath Rathayibacter sp. VKM Ac-2759
Pathway
rath00300
Lysine biosynthesis
rath00550
Peptidoglycan biosynthesis
rath01100
Metabolic pathways
rath01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rath00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GSU68_07770 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GSU68_07770 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GSU68_07770 (murF)
Enzymes [BR:
rath01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GSU68_07770 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QHC66483
UniProt:
A0A6P1FAZ9
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Position
1694066..1695490
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AA seq
474 aa
AA seq
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MIALTLTEIAAAVSGRLHLAGASSNASTVVSGATETDSREIAPGGIFVAKRGEHTDGHLF
APVAVENGAALLIVERPLDLDVPQVLVEDSVEALGALATEVVRRVRALGGLTVVGVTGSN
GKTTTKNLLRTVLERVGETVAPRGSFNNEVGAPITMLQVSESTRFLVAEMGASAVGEIRR
LVRMAKPDVGVVLAVGLAHAGEFGGIERTLEAKTEMVADLTADDVAVLNVDDGRVASMAG
RTAARVLWFGRGEGADVRAVDVESSAEGTRFTIEVTAGEGREAGRAELFLRVLGEHHVMN
ALAATAAALSVGVPLPSIVEALSTVTLAERWRMQVLGGPDVTVVNDAYNASPDSTAAALR
TLAQIARPGGRTVAVLGEMSELGEWADEEHDRVGLLAVRLNIAQIVVVGAGARRIHVAAE
REGSWSGESVFVETADEAYALLEGYLQSGDTVLVKSSNSAGLRFLGDRLGERHR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccctgaccctcaccgagatcgccgccgccgtctccggtcggctccacctcgcc
ggcgcgtcctcgaacgcgtcgaccgtcgtcagcggagcgaccgagaccgactcccgcgag
atcgcgccgggcgggatcttcgtcgccaagcgcggcgagcacaccgacggccacctcttc
gcgccggtcgccgtcgagaacggcgcggccctgctgatcgtggagcgcccgctcgacctc
gacgtcccgcaggtgctggtcgaggactccgtcgaggcgctcggcgccctggcgaccgag
gtcgtccgccgcgtgcgcgccctgggcggcctcaccgtcgtcggcgtgaccggctcgaac
ggcaagaccacgaccaagaacctgctgcgcaccgtgctcgagcgggtcggcgagaccgtc
gcgccccgaggctccttcaacaacgaggtcggtgcgccgatcacgatgctccaggtgtcg
gagtcgacacggttcctcgtcgccgagatgggcgccagcgccgtgggcgagatccgccgc
ctcgtgcggatggccaagcccgacgtcggcgtcgtcctcgccgtcggcctggcgcacgca
ggggagttcggtgggatcgagcgcaccctcgaggccaagaccgagatggtcgccgacctc
acggccgacgacgtcgccgtgctcaacgtcgacgacggccgtgtcgcgtcgatggcgggc
cgcaccgccgcccgcgtgctctggttcgggcgcggcgagggcgccgatgtgcgcgccgtc
gatgtcgagtcctcggctgagggcacgcgcttcaccatcgaggtcaccgccggcgagggc
cgcgaggcgggccgggccgagctgttcctccgcgtcctcggcgagcaccacgtcatgaac
gccctcgcggcgacggctgcggcgctctcggtcggcgtccccctcccgtcgatcgtcgag
gcgctctcgacggtcacgctcgccgagcgctggcggatgcaggtcctcggcggcccggac
gtgaccgtcgtcaacgacgcgtacaacgcctcgcccgactccaccgccgccgccctgcgg
accctcgcgcagatcgcgaggcccggcggccgcacggtcgccgtgctcggcgagatgagc
gagctgggggagtgggccgacgaggagcacgaccgcgtgggactcctggccgtgcgcctg
aacatcgcgcagatcgtcgtcgtcggcgccggagcgcgccgcatccacgtggccgccgag
cgcgaggggtcctggagcggcgagtccgtcttcgtcgagaccgccgacgaggcgtacgcg
ctcctcgagggctacctgcagagcggtgacaccgtgctggtgaagtcgtccaactccgcc
ggcctgcgattcctcggcgaccgactcggggagcgtcaccgatga
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