Rousettus aegyptiacus (Egyptian rousette): 107500054
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Entry
107500054 CDS
T06036
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
107500054 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ray03032
]
107500054 (TOP2B)
03036 Chromosome and associated proteins [BR:
ray03036
]
107500054 (TOP2B)
Enzymes [BR:
ray01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
107500054 (TOP2B)
DNA replication proteins [BR:
ray03032
]
Eukaryotic type
DNA Topoisomerases
107500054 (TOP2B)
Chromosome and associated proteins [BR:
ray03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
107500054 (TOP2B)
Centrosome formation proteins
Centriole proteins
107500054 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
107500054
NCBI-ProteinID:
XP_015980349
UniProt:
A0A7J8HXL8
LinkDB
All DBs
Position
Unknown
AA seq
1620 aa
AA seq
DB search
MAKAGGGGAGAGGNGALTWVTLFDQNNAAKKEESETANRNDSSKKLSVERVYQKKTQLEH
ILLRPDTYIGSVEPLTQLMWVYDEDVGMNCRDITFVPGLYKIFDEILVNAADNKQRDKNM
TCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDEEKKVTGGR
NGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSESKIKHFDGEDYTCITFQPD
LSKFKMEKLDKDIVALMTRRVYDLAGSCKGVKVIFNGKKLPVNGFRSYVDLYVKDKLDET
GVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVK
KKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKNFGSKCQLSEKFFKAA
SNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEG
DSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSY
DDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASK
NKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAG
PEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKE
LILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQ
ALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARRLFPPVD
DNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDG
LDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEP
MLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVL
FDHMGCLKKYETVQDILKEFFDLRLSYYGLRREWLVGMLGAESAKLNNQARFILEKIQGK
ITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKATEEEETQNQHDDSSSDSGTPSGPDF
NYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFAEELDKVEAQE
REDILAGMAGRTIKGKVGKPKVKKLQLDETMPSPYGRRIVPEITAMKADASKKLLKKKKG
DLDTTTVKVEFDEEFSGTPVEGAGEEALMQPVPVNKGPKPKREKKEPGTRVRKTPASSGK
SSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAD
DDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKTTPEKSSHDKKSQDF
GNLFSFPSYAQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTT
PKPRRTPKQKKVETINSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
KPPSKKQKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcgcgggagctggcggcaacggggcactgacctgggtg
actctttttgatcagaacaatgctgcaaaaaaagaagagtccgaaactgcaaatagaaat
gattcttcaaagaaattgtctgttgagagagtatatcagaaaaagacacaacttgaacac
attctccttcgtcctgatacatacattgggtcagtggagccattgacacagttaatgtgg
gtgtatgacgaagatgtgggaatgaattgcagggatattacctttgtgccaggtttatac
aagatctttgatgaaatcttggttaatgcagctgacaataaacagagggataagaacatg
acctgtattaaagtttctattgatcctgaatctaacattataagcatttggaataatggg
aaaggcattccagtggtagaacacaaagtagagaaagtttatgttcctgcattaattttt
ggccagcttttaacatccagtaactatgatgatgaggagaaaaaagtaacaggtggtcgc
aatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgct
tgcaaagaatacaaacatagttttaagcagacctggatgaataatatgatgaagacttca
gaatccaaaattaagcatttcgatggcgaagattacacatgcataacattccaaccagat
ctgtccaaatttaagatggaaaaacttgacaaggatattgtggctctcatgaccagaaga
gtttatgatctggctggttcatgcaaaggggtcaaggtcatatttaatggaaagaaattg
cctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattggatgaaact
ggagtggctctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcaca
ttgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggt
ggacggcacgtggattatgtagtagatcaagttgttggtaaactgattgaagtagtgaag
aaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaatcatatatgggtt
tttattaattgccttatcgaaaatccaacttttgattctcagactaaagaaaacatgact
ttgcagcccaaaaattttgggtccaaatgtcagctgtcagaaaaatttttcaaagcagcc
tctaactgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagactcag
ctgaacaagaagtgttcatcagtaaagtacagtaaaatcaaaggtattcccaaactggat
gatgctaatgatgctggtggcaaacattccctagagtgtacactgatactaacagaggga
gactcagccaaatcactagctgtgtctggattaggtgtgatcgggcgagatagatatgga
gtctttccactcaggggaaaaattcttaatgtacgagaagcttctcataaacagatcatg
gaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaaaaaaagctat
gatgatgcagaatctctgaaaactttacgctatggaaagattatgattatgactgatcag
gatcaagatggttctcatataaaaggccttcttattaatttcatccatcacaattggcca
tcacttttgaagcacggttttcttgaagagttcattactccaattgtaaaggcaagcaaa
aataagcaggaactttccttctacagtattccagaatttgatgagtggaaaaaacatata
gaaaaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtacagctaaa
gaagcaaaggaatattttgctgatatggaaaggcatcgcatcttgtttagatatgctggt
cctgaagatgatgctgctattaccttggcgttcagtaaaaagaagatcgatgacagaaaa
gaatggttaacaaattttatggaagaccggagacagcgtaggttacatggcttaccagag
caatttttatatggtacagcgacaaagcatttgacgtacaatgatttcatcaacaaggaa
ttgattctcttttcaaattcagacaatgaaagatctataccatctcttgttgatggcttt
aaaccaggccaacgaaaagtgttatttacctgtttcaagagaaatgataaacgtgaagta
aaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaacaa
gcattgatgatgactattgtaaatttggctcagaactttgtgggaagtaacaacattaac
ttgcttcagcctattggtcagtttggaactcgacttcatggtggcaaagacgccgcaagc
cctcgttatattttcacaatgttaagctctttagcaagacggctttttcctcctgtggat
gacaacctgcttaaattcctgtatgatgataatcaacgtgtagagcctgagtggtatatt
cccataatccccatggttttaataaatggtgctgagggcattggtactggatgggcttgt
aaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggc
ttggatcctcatcccatgcttccaaactacaaaaactttaaaggaacgatccaagaactt
ggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagaa
attacagagcttccagttagaacttggacacaggtatacaaagaacaggttttagaacct
atgctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcatact
gatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagct
gctggtttgcataaagtttttaagcttcaaacgactctcacttgtaattccatggtactc
tttgatcatatgggctgtctgaagaagtatgaaactgtacaggatattttgaaagaattt
tttgatttacgactaagttattatggtttacgtagggagtggcttgtagggatgttggga
gcagaatctgcaaagcttaacaatcaagctcgtttcattttagagaagatacaaggaaaa
attactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttat
gaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcaacagaagaggaagaa
acacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccctgatttt
aattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaattgatt
aaacagagagatgcgaaaggacgagaggtcaatgatcttaaaagaaaatctccttcagat
ctttggaaagaagatttagcagcatttgctgaagaactggataaagtggaagctcaagaa
cgagaagatattctggctggaatggctggaagaacaataaaaggtaaagttggaaaacct
aaggtgaagaaacttcagttggatgagactatgccctcaccttatgggaggagaattgtt
cccgaaatcactgctatgaaggcagatgccagcaaaaagttgttgaagaagaaaaagggt
gatcttgataccacaacagtaaaagtggaatttgatgaagaattcagtggaacaccagta
gaaggtgcaggcgaggaggcattgatgcagccagtgcctgtaaataaaggtcccaaaccc
aaaagggaaaaaaaggagcctggtaccagggtgagaaaaacacctgcatcatctggtaaa
tctagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaa
agtgacttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcg
gctgctgaaaggcctaagtacacgtttgatttctcagaagaagaggatgatgatgctgat
gatgatgatgacaataatgatttagaggaattaaaagttaaagcatctcccataacaaat
gatggggaagatgagtttgttccttcagatggcctagataaagatgaatatacattttca
ccaggcaaatcaaaaactactccagaaaaatcttcgcatgataaaaaaagtcaggatttt
ggaaatcttttctcatttccttcatacgctcaaaagtcagaagatgattcagctaaattt
gacagtaacgaagaagattctgcttctgttttttcaccgtcatttggtctgaaacaaaca
gataaagtaccaagtaaaacagtagctgctaaaaaaggaaaaccatcttcagatacaact
cctaagcccaggagaactcccaaacagaagaaagtagagactataaactctgactcagat
tcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggtcgaggggcaaag
aaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatcc
aaaccaccaagcaagaaacagaagaaaacatcttttgatcaggattcggatgtggacatc
ttcccatcagacttcacttctgaaccaccttctctgccacggacgggtcgggctaggaaa
gaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaat
taa
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