Rousettus aegyptiacus (Egyptian rousette): 107501522
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Entry
107501522 CDS
T06036
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00230
Purine metabolism
ray01100
Metabolic pathways
ray04927
Cortisol synthesis and secretion
ray04934
Cushing syndrome
ray05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107501522 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
107501522 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
107501522 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
107501522 (PDE8B)
Enzymes [BR:
ray01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
107501522 (PDE8B)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
JetB
Motif
Other DBs
NCBI-GeneID:
107501522
NCBI-ProteinID:
XP_015983238
LinkDB
All DBs
Position
Unknown
AA seq
884 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPTARLHGLFVQTDAADAVPQSRASG
PPGAVRIRRARAELGSGSSADSAAPTTTTCRGRRRHCCSSAEAETQTSYSSVKVSSAEVR
IGPMRLTQDPIQVLLIFAKEDNQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIV
IDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQALGDHEEASVLPLLHAGFNRRFMEN
SSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERM
MGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKI
TPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKVHRDSGDNSQTESHSFRYRNRRKESIDVK
SISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEI
LRTTELYSPQLGTKDDDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLSMPITIN
DVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLRCSETTLRAWL
QVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDGVAALIAATVHDVDHPG
RTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAII
DMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPIGKNFPENQTLIKRMMIKCAD
VANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDN
NT seq
2655 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gatgagtccaactcgccccggcagaccaccagcgtgtcgcagggccccacggcccggctg
cacggcctcttcgtccagaccgacgccgccgacgccgtgccccagagccgcgcgtcggga
ccccccggcgctgtccgcatccgccgggcccgcgctgagctgggcagtggcagcagcgcg
gactctgcagcccccaccacgaccacctgcaggggccggaggcgccactgctgcagcagt
gccgaggccgagacccagaccagctactccagcgtcaaggtttcttctgcggaggtacgc
attgggcccatgagactgacacaggatcctattcaggttttgctgatctttgcaaaagaa
gataaccagagtgatggcttctggtgggcatgtgacagagctggttatagatgcaatatc
gctcggactccagagtcagcccttgaatgctttctagataaacatcatgaaattattgta
attgatcacagacaaactcgaaattttgatgcagaagcggtgtgcaggtctatccgggcc
acaaatccctctgagcacacggtgatcctcgcagtggtttcacaagcattgggcgaccat
gaagaggcctcagttctcccccttctgcatgcaggcttcaacaggagatttatggagaat
agcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgctcg
cagttcaaattacgggcctgtaattcagtgtttacagcattagaccactgtcatgaagcc
atagaaataaccagcgatgaccatgtgattcagtatgtcaaccccgccttcgaaaggatg
atgggctaccacaaaggtgaactcctggggaaagaactcgcagagctgcccaaaagcgat
aagaaccgggcagacctcctcgacaccattaacacgtgcatcaagaagggcaaggagtgg
cagggggtttactatgccagacggaaatccggggacagcatccagcagcatgtgaagatc
actccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgt
tgtaccactgacaataataagcagattcacaaggttcatcgtgattcaggagacaattct
cagacagagtctcattcattcagatacaggaacaggaggaaagagtccattgatgtgaaa
tcaatatcatctcgaggcagtgatgcaccaagcctacagaatcgtcgctatccatccatg
gcaaggatccactccatgaccatcgaggctcccatcacaaaggttataaatataatcaat
gcagcccaagaaaacagccccgtcacagtagcagaagccttggacagagttttagaaatt
ttacggaccacggaactatactcccctcagctgggtaccaaagatgacgatcctcacacc
agtgatctcgtaggaggcctgatgactgatggcttgagaaggttgtcaggaaatgagtat
gtgttcactaagaatgtgcaccagagtcacagtcacctttcaatgccaataaccatcaat
gatgtccccccttgcatcgctcaattacttgataatgaggaaagttgggagttcaacatc
tttgaactggaagctgttacacataaaaggccattggtctatctgggcttaaaggtcttt
tcccggtttggagtatgtgaatttttacgctgttctgaaactactcttcgggcctggctc
caagtgatcgaagccaactaccactcctccaatgcctaccacaactccacccatgctgcc
gacgtcttgcatgccaccgccttcttcctggggaaggaaagagtgaagggaagcctcgat
cagctggatggggtggcggcactgattgctgccacggtccatgacgtggaccacccagga
aggaccaactctttcctgtgcaatgcaggcagtgaacttgctgtgctttataatgacacc
gccgtcttggagagtcaccacacagccctggccttccagctgacggtcaaggacagcaag
tgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctattatt
gacatggttttagcaacagagatgacaaaacactttgaacatgtgaacaaatttgtgaac
agcatcaacaagccaatggcagctgagattgagggcagtgactgtgaatgcaaccccatt
gggaagaactttcctgaaaaccaaactctgatcaagcgcatgatgattaagtgtgccgat
gtggccaacccttgccgccccctggacctgtgcatcgaatgggctgggaggatctctgag
gagtactttgcacagactgatgaagagaagagacaggggctaccagtggtgatgccagtg
tttgaccggaatacctgtagcatccccaagtcccaaatctccttcattgactacttcata
acagacatgtttgatgcctgggatgcctttgcacatctgccagccctgatgcaacatttg
gctgataactacaaacactggaagacattagatgacctgaagtgcaaaagtctgaggctt
ccatctgacaactaa
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