Rousettus aegyptiacus (Egyptian rousette): 107505049
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Entry
107505049 CDS
T06036
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
107505049 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ray01002
]
107505049 (BACE1)
Enzymes [BR:
ray01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
107505049 (BACE1)
Peptidases and inhibitors [BR:
ray01002
]
Aspartic peptidases
Family A1: pepsin family
107505049 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
107505049
NCBI-ProteinID:
XP_015990381
LinkDB
All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGSAVLPAHCTQPGIRLPLRSGLGGTPLGLRLPRDTDEELEDPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVIFDRARKRIGFAVSSC
HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcactgccctggcttctgctgtggatgggctcagcagtgctgcctgcccac
tgcactcagcctggcatcaggctgcctctgcggagtgggcttggggggactcctctggga
ctgaggctgccccgggacactgacgaagagctggaggatcctggccggaggggcagcttt
gtagagatggtggacaacctgaggggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacaggaagcagtaactttgca
gtgggggctgcccctcacccttttctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggcgtgtatgtaccctatacccaggggaagtgggagggggag
ctgggcaccgacctggtgagcatcccccatggccccaatgtcactgtgcgtgccaacatt
gctgccatcactgaatcagacaagttcttcattaacggctccaactgggaaggcatcctg
gggctggcctatgctgagatcgccaggcccgatgactctctggagcctttctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctttgtggtgctggcttc
cccctcaaccagtcagaagcgctggcctcagttggagggagcatgatcattggaggtatt
gaccactcactatacacaggcagcctctggtacacacccatccggcgggagtggtattat
gaggtgatcattgtgcgggtagagatcaatggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgcagtcaaatccatcaaggcagcctcctcgacagagaagtttccagat
ggcttttggctaggggaacagctggtgtgctggcaagcagggactactccttggaacatt
ttccccgtcatctcactctacctaatgggtgaagtgaccaatcagtccttccgcatcacc
atccttccacagcaatacctgcgtccagtggaagacgtggccacgtcccaagacgactgt
tacaagtttgccatctcacagtcatccacgggcactgttatgggagctgttatcatggag
ggcttctatgtcatctttgatcgggcccgaaaacgaattggctttgctgtcagttcttgc
catgtacacgatgagttcaggacggcagcagtggaaggcccttttgtcaccctggacatg
gaagactgtggctacaacattcctcagacagatgaatcaacactcatgaccattgcctat
gtcatggctgccatctgcgccctcttcatgctgccactctgcctcatggtgtgtcagtgg
cgctgtctccgctgtctacgccatcaacatgatgactttgctgatgacatctccctgctg
aagtga
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