Rousettus aegyptiacus (Egyptian rousette): 107505180
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Entry
107505180 CDS
T06036
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00190
Oxidative phosphorylation
ray01100
Metabolic pathways
ray04714
Thermogenesis
ray04723
Retrograde endocannabinoid signaling
ray04932
Non-alcoholic fatty liver disease
ray05010
Alzheimer disease
ray05012
Parkinson disease
ray05014
Amyotrophic lateral sclerosis
ray05016
Huntington disease
ray05020
Prion disease
ray05022
Pathways of neurodegeneration - multiple diseases
ray05208
Chemical carcinogenesis - reactive oxygen species
ray05415
Diabetic cardiomyopathy
Module
ray_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
107505180 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
107505180 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
107505180 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
107505180 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
107505180 (NDUFS1)
05012 Parkinson disease
107505180 (NDUFS1)
05014 Amyotrophic lateral sclerosis
107505180 (NDUFS1)
05016 Huntington disease
107505180 (NDUFS1)
05020 Prion disease
107505180 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
107505180 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107505180 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
107505180 (NDUFS1)
Enzymes [BR:
ray01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
107505180 (NDUFS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
107505180
NCBI-ProteinID:
XP_015990567
LinkDB
All DBs
Position
Unknown
AA seq
733 aa
AA seq
DB search
MDKKLNMLRIPVRRALVGLSKSHTGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACE
KVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKARE
GVMEFLLANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMT
RCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNVIDICPVGALTSK
PYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAY
DGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMFQSFQGKDVAAIAGGLVDAEALVAL
KDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLIGTNPRFEAPLF
NARIRKSWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMV
VLGSSALQRNDGAAILAAVSSIAQKVRMSSGVTGDWKVMNILHRIASQVAALDLGYKPGV
EAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSA
TYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQIRNRLEEVSPNLV
RYDDVEGANYFQQASELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAV
TEGAQAVEEPSIC
NT seq
2202 nt
NT seq
+upstream
nt +downstream
nt
atggacaaaaaactcaatatgttaaggatacctgtaagaagggccttagtaggcctttct
aagtctcatacaggatgtgtcagaacaactgccacagctgcaagcaacttgattgaagta
tttgttgatggtcaatctgtcatggtggaaccaggaactaccgttctccaagcttgtgag
aaggttggcatgcagatccctcggttctgttatcatgaaaggttgtctgttgctggaaac
tgcaggatgtgcctcgttgaaattgagaaagcgcctaaggttgtagctgcttgtgccatg
ccagtaatgaaaggttggaatatcctgacaaactcagagaaatctaagaaagccagagaa
ggtgtgatggagtttttattagcaaatcacccactggactgccctatttgtgaccaggga
ggtgaatgtgatctgcaggatcaatccatgatgtttggaagtgataggagccgattttta
gaggggaaacgtgctgtggaggacaagaacattgggccattggtaaagaccattatgaca
agatgtatacagtgtactcgctgcatcaggtttgcaagtgagattgcaggagtagatgat
ttgggaacaacaggcagaggaaatgatatgcaagttggcacatacattgaaaagatgttc
atgtctgaactgtctgggaatgtcattgatatctgtcctgtaggtgcattgacctctaag
ccctatgcttttactgctcggccttgggaaacaagaaagacagaatccatcgatgtaatg
gatgcagttggaagtaacattgtcgtaagcacaagaactggagaggtgatgaggattttg
ccaaggatgcatgaggacatcaatgaagagtggatctctgataaaactagatttgcctat
gatgggctgaaacgtcaaagacttactgagccgatggtcagaaacgaaaaggggctttta
acctatacctcctgggaggatgcactctctcgtgtagctggaatgtttcagagttttcaa
ggcaaggatgtcgcagcaattgcaggtggcttggtggacgccgaagccctagtagctctc
aaagatttgcttaatagagtggactctgacaccctctgcactgaagaggtcttcccaact
gcaggagctggcacagatttgcgttctaattatcttctaaatactacaattgctggtgtg
gaagaggcagatgttgtccttctgattggtacaaatccacgatttgaggcaccactattt
aatgctagaattcgaaagagctggcttcataatgacttaaaagtggcacttataggcagt
cctgtggatctcacttacagatatgaccatctgggagattcccccaaaattcttcaagac
attgcttcgggtagtcatccattcagccaggtcctaaaggaagctaaaaaaccaatggtg
gttttaggcagttctgctctccaaagaaacgatggggcagcaattcttgcagctgtttcc
agcatcgctcaaaaggttcgaatgagtagtggtgttactggtgattggaaagttatgaat
atccttcataggattgcaagccaagtagctgctttagaccttggctataaacctggggtg
gaagcaattcggaagaaccctcccaaagtactattcctcctaggtgcagatggaggttgt
atcactcgtcaggatttgccaaaggattgtttcattatttatcaaggacatcatggtgat
gttggagctcctatagctgatgtcattctcccaggcgctgcttacacagagaagtctgct
acttatgtcaatactgaaggccgagctcagcagactaaagtagcagtgacacctcctggc
ttggcaagagaagactggaaaattataagagccctctcagagattgcaggtataactctt
ccgtatgatactctggatcaaataaggaacagattggaagaagtctctcctaatcttgtt
cggtatgatgacgttgaaggagctaattacttccagcaagcaagtgagctctccaagcta
gtgaaccagcaacttcttgctgatccacttgttccaccccagctaacgataaaagacttc
tacatgacagattcaattagcagagcctcacagacaatggccaaatgtgtcaaagctgtc
acagagggtgcccaggcagtagaagaaccatccatatgctga
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