Rousettus aegyptiacus (Egyptian rousette): 107505341
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Entry
107505341 CDS
T06036
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00230
Purine metabolism
ray01100
Metabolic pathways
ray04927
Cortisol synthesis and secretion
ray04934
Cushing syndrome
ray05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107505341 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
107505341 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
107505341 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
107505341 (PDE8A)
Enzymes [BR:
ray01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
107505341 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PDE8
PAS_4
PAS_3
PAS_8
DUF5894
Response_reg
Sina_ZnF
Motif
Other DBs
NCBI-GeneID:
107505341
NCBI-ProteinID:
XP_015990901
LinkDB
All DBs
Position
Unknown
AA seq
869 aa
AA seq
DB search
MGCAPSIHISESREAFHGGKEAEDAPGPAAPLPPGRRSLPRRQTTATPGSRGAGLAEPKP
RGRSSSNSSSSSSTVAVADVQFGPMKFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCT
VTKEAQAVLACFLAKHHDIIIIDHRNPRQLDAEALCRSIRSSKFSENTVIIGVVRRADRE
ESSVMPLIAAGFTRRYVENPSLMACYNELLQLEFGEVRSQLKLRACNSVFAALEKSQEAV
EITSEDHMIQYANPAFETTMGYESGELIGKKLAEVPINEKKADLLDTINSYIRMGKEWQG
ICYAKNGDNVQQNVKIIPVTGQGGRIRHYVSIIRVCSGSSKAEKIAECVQSDRHAGGAAV
NRVKKEAWERDPQVEGSRLLRHRDNQSGKQKDKRKSSLDFRAIGHRANEVASQRRHSSMA
RIHSMTIEAPITKVINIINAAQENSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHAN
DLVGGLMSDGLRRLSGNEYVLSTKNLQQISSNIVTPISLHDVPPRIAQAIENEDYWDFDI
FELEAATQKRPLVYLGLKIFARFGICEFLNCSEATLRTWFQLIEANYHSSNPYHNSTHSA
DVLHATAYFLCRERIKQTLDPVDEAAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDT
AVLESHHAALAFQLTIRDDKCNIFKNMERNDYRTLRQAIIDMVLATEMTKHFEHVNKFVN
SVNKPLAALEVNEETDKEQAAINTVLRTPENRTLIKRMLIKCADVSNPCRPLEQSIEWAA
RISEEYFSQTDEEKRQDLPVVMPVFDRNTCSIPKSQISFIDYFITGMFDAWDAFVDLPEL
LQHLDNNFKYWKGLDERKLRSLRPPTEPQ
NT seq
2610 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgccccgagcatccacatttccgagagtcgggaggcgttccacggcggcaag
gaggccgaggacgcgccgggccccgcggcgccgctgccgcccggccggcggagcctccct
cggcgccagaccaccgccactcccgggtcccgcggcgccggcctcgcggagcccaagcct
cgcggccgcagcagcagcaacagcagcagcagcagcagcacagtagcagtagctgatgtg
caatttggccccatgaaattccatccggatcaactccaggtacttttagtgtttaccaaa
gaagataaccagtgtaatggattctgcagggcgtgtgaaaaggcagggtttaagtgtaca
gttactaaggaggctcaggctgtccttgcctgtttcctggccaaacatcatgacatcatc
atcatcgaccacagaaacccccgacagctggacgcagaggcactgtgcaggtcgattcga
tcatcaaaattttcagaaaacacggttattattggtgtagtacgcagggcggatagagaa
gagtcatctgtaatgcccctcattgctgctggcttcacaagaaggtatgtggagaacccc
agcctcatggcctgttacaacgagctgctccagctggagtttggagaggtgcgatcgcag
ctgaaactcagggcttgtaactcagtattcgctgcgttagagaaaagccaagaagcagtt
gaaatcacaagcgaagaccacatgatacagtatgcaaatcctgcatttgaaacaacaatg
ggctatgagtcaggtgaattaatagggaagaagttagccgaagtgcctataaatgaaaaa
aaggctgatttgctcgatactataaattcatacatcaggatgggcaaggagtggcaagga
atttgctatgccaaaaatggagataatgtacaacaaaatgtgaagataatacctgtcact
ggacagggaggaagaattagacactatgtgtccattatcagagtgtgcagtggcagcagc
aaggctgagaaaatagcagaatgtgttcagtctgacagacacgcaggaggagcagcagtt
aaccgggtgaagaaggaggcctgggagagggaccctcaggtggagggaagccgtctgctg
aggcacagagataatcagtcaggcaaacagaaagacaagagaaaaagctcactagacttc
agagccattggccatcgcgcaaatgaagtggccagccagagacgacactcctccatggcc
cggatacactccatgaccatcgaggcgcccatcaccaaggttatcaacattatcaatgct
gcgcaggaaaacagtcccatgcctgtgacagaagccttagaccgtgtgctagaaattctc
agaaccactgagttatactcaccgcagtttggtgctaaggacgatgaccctcacgccaat
gacctcgtcgggggcctaatgtccgatggtttacgaagactatctggaaatgaatatgtt
ctttcaacaaaaaaccttcaacagatttcaagcaatatagtcactcccatctcccttcac
gatgtcccaccgcggatagctcaggccatagaaaacgaggactactgggattttgatatt
tttgaactggaggccgccactcagaaaaggcctttagtttatcttggtctcaaaatcttc
gctcgctttggaatctgtgaattcttaaactgctccgaggcaacactgagaacgtggttc
cagcttatcgaagccaattaccattcctcaaacccgtaccacaactccacacattctgcc
gacgtgcttcacgccactgcctacttcctctgcagagagaggataaagcaaacgctagat
cccgtcgacgaggccgctgccctcattgcagccaccattcatgacgtggaccaccccggg
aggaccaactccttcctgtgtaacgctggaagcgagctggccattctgtacaatgacact
gcggtgctggagagccaccatgcagccttggccttccagctgaccatcagagatgacaaa
tgcaatatcttcaagaacatggagaggaatgattaccggacgctgcgccaggctatcatt
gacatggtcttggccacagagatgacaaagcatttcgagcacgtcaacaagtttgtcaac
agcgtcaacaagcccctggcggcgctggaagtaaacgaggaaacagataaagagcaagca
gccataaacaccgtgctcaggacgccggagaaccggactctgatcaagcgcatgctgatc
aagtgcgcggacgtgtccaacccctgccgaccgctggagcagagcatcgagtgggccgcg
cgcatctcggaggagtacttttcccagaccgatgaagagaagcggcaggacttacctgtg
gtgatgcccgtgtttgacagaaacacctgcagcattcccaagtctcagatctcgttcatt
gactacttcatcacaggcatgttcgatgcttgggacgccttcgtggacctgccagagctg
ctgcagcatctcgataacaacttcaaatactggaaaggactggacgaaaggaagctgagg
agcctccggccgcccacggaaccccaataa
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