KEGG   Rousettus aegyptiacus (Egyptian rousette): 107505355
Entry
107505355         CDS       T06036                                 
Symbol
CACNA1B
Name
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B isoform X4
  KO
K04849  voltage-dependent calcium channel N type alpha-1B
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04020  Calcium signaling pathway
ray04721  Synaptic vesicle cycle
ray04723  Retrograde endocannabinoid signaling
ray04725  Cholinergic synapse
ray04726  Serotonergic synapse
ray04727  GABAergic synapse
ray04728  Dopaminergic synapse
ray04930  Type II diabetes mellitus
ray05016  Huntington disease
ray05020  Prion disease
ray05022  Pathways of neurodegeneration - multiple diseases
ray05032  Morphine addiction
ray05033  Nicotine addiction
ray05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107505355 (CACNA1B)
   04020 Calcium signaling pathway
    107505355 (CACNA1B)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    107505355 (CACNA1B)
   04725 Cholinergic synapse
    107505355 (CACNA1B)
   04728 Dopaminergic synapse
    107505355 (CACNA1B)
   04726 Serotonergic synapse
    107505355 (CACNA1B)
   04723 Retrograde endocannabinoid signaling
    107505355 (CACNA1B)
   04721 Synaptic vesicle cycle
    107505355 (CACNA1B)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    107505355 (CACNA1B)
  09164 Neurodegenerative disease
   05016 Huntington disease
    107505355 (CACNA1B)
   05020 Prion disease
    107505355 (CACNA1B)
   05022 Pathways of neurodegeneration - multiple diseases
    107505355 (CACNA1B)
  09165 Substance dependence
   05032 Morphine addiction
    107505355 (CACNA1B)
   05033 Nicotine addiction
    107505355 (CACNA1B)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    107505355 (CACNA1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:ray04040]
    107505355 (CACNA1B)
Ion channels [BR:ray04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   107505355 (CACNA1B)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel Phage_TAC_15
Other DBs
NCBI-GeneID: 107505355
NCBI-ProteinID: XP_015990941
LinkDB
Position
Unknown
AA seq 2330 aa
MVRFGDELGGRYGGAGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGVFCFEAGIKIVALGFALHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFPNSTDADPTGDFPCGPEPPARVCEGDTECREYWPGPNFGITNFDNI
LFSVLTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
TKKSRNDLIHAEEGEDRFADLCAGGSPFARAGLKSGKTESSSYFRRKEKMLRFLVRRVVK
AQSFYWAVLCVVALNTLCVAMVHHNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPRS
YFRSSFNCFDFGVIVGSIFEVVWAAIKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLVV
SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFKDETPTTNFDTFPAAILTVFQIL
TGEDWNAVMYHGIESQGGVSKGMFSSCYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
DEEEMEEAANQKLALQKAKEVAEVSPVSAANVSVAARQQSSAKARSVWEQRASQLRLQNL
RASCEALYSELDPEERLRYATTRHLRPDMKTHLDRPLVVEPSRNGPRGPAAGKAQPEGAE
ATEGTDPPRRHHRHRDKDKAPAPAAGEPERADAPKAEGGEPVAREERVRPHRSRNKEVRS
GRGRGPGPEGGRRHHRHGSPEEAAEREPRRHRTHRHAPDQGKEGSAPGAKGERRARHRGG
TRAGAREPESMEEPARRHRARHRAPPTHEDAEKEAEEKEGETQDRDRDKEVRNHQPKEPR
GDLGDGGVTAVGPVHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPADPGAPVHIPAAPTG
PPAEGTVVPSGSGDLESQADGRKAAEAEDVTRSGPRPIVPYSSMFCLSPTALLRRCCHYI
VTMRYFEMVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLG
LLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLP
KLKAVFDCVVNSLRNVLNILVVYVLFMFIFAVIAVQLFKGKFFYCTDESKERERDCRGQY
LDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSP
GYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISA
RPLTRYMPRDKQSLQYKTWTFVVSPPFEYFIMAMIALNTLVLMMKFYGAPYEYELLLKGL
NVAFTSVFSMECLLKIVAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNNFINLSF
LRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIAL
DDDSSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSDRACDEHASASACGSDFAYF
YFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISY
SDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISSEDMTVHFTSTLMALIRTALEIK
LAPAGTTQHQCDAELRKEISSVWANLPQKTLDLLVPPHKPDEVTVGKVYAALMIFDFYKQ
SKSSRDQTHQAPGGLTQMGPVSLFHPLKATLEQTQPAVLRGARVFLQQKSSTSLSNGGAV
QTQESGIKESVSWGTQRTQDMLCESRRPLERGHSTEIPVVQPGKPAADVQTQSMALRGPD
GEPQPGLESQGRAASMPRLAAETQPAPGASPMKRSVSTLAPQRPRAAPLCNAAPDRAPAG
PAAAHHHHRCHRRRDRKQKSLEKGPSLSADTDGAPHSAGPGPPPAEGPAGGRRERRQERG
RSQERRQPSSSSSEKQRFYSCDRFGGREPPHPRPSLSSHPTSPTAGQEPGPLRQGGGSAN
GSPLLSASGASTPGRGGRRQLPQTPLTPRPSVTYKTAHSSPVHFAGAQTSLPAFSPGRLS
RGLSEHNALLQRDPLSQPLAPSSRTGSDPYLGQRLDGETTARTQPEDALTFEEAVATNSG
RSSRTSYVSSLTSQPHPPRRVPNGYHCTLGPGPGSRARLSAHHPDRDHWC
NT seq 6993 nt   +upstreamnt  +downstreamnt
atggtccgcttcggagacgagctgggcggccgctatgggggcgccggcggcggggagcgg
gcccggggcggcggggccggcggggccggcggcccgggccccggggggctgcagccgggc
cagcgggtcctctacaagcagtcgatcgcgcagcgcgcgcgcaccatggcgctgtacaac
cccatcccggtcaagcagaactgcttcaccgtcaaccgctcgctcttcgtcttcagcgag
gacaacgtcgtccgcaaatacgccaagcgcatcacggagtggcctccgtttgagtacatg
atcctggccaccatcatcgccaactgtatcgtgctggcactggagcagcaccttcctgac
ggcgacaagacgcccatgtccgagcggctggacgacacggagccctacttcatcggcgtc
ttctgcttcgaggcgggcatcaagatcgtcgccctgggcttcgcgctgcacaagggctcc
tacctacgcaatggctggaacgtcatggacttcgtggtggtcctcacggggatcctggcc
acagctggcactgacttcgacctgcgaacgctacgtgctgtgcgcgtgctgaggcccctg
aagctggtgtccgggatccccagtttgcaggtggtgctcaagtccatcatgaaggccatg
gtcccactcctgcagattgggctgctcctcttctttgccatcctcatgttcgccatcatt
ggcctggagttctacatgggcaaattccacaaggcctgtttccccaacagcacagatgca
gatcccactggtgacttcccctgtggcccagagccccctgcccgggtgtgtgagggcgac
accgagtgccgggagtactggccagggcccaacttcgggatcaccaacttcgacaacatc
ctgttctccgtcctgacggtgttccagtgcatcaccatggagggctggactgacatcctc
tacaatacaaacgacgcggccggcaacacgtggaactggctctacttcatccctctcatc
atcatcggctccttcttcatgcttaacctggtgctgggcgtgctctctggcgagtttgcc
aaggagcgcgagcgggtggagaaccggcgggccttcctgaagctgcgccggcagcagcag
atcgagcgggagctcaacggatacctggagtggatcttcaaggccgaggaagtcatgctg
gctgaggaggacaggaatgcagaggagaagtcccctctggatgtgctgaagagagcagcc
accaagaagagccggaacgacctgatccacgcagaggagggcgaggaccgcttcgcagac
ctctgtgccggggggtcccccttcgcccgcgccggcctcaagagtgggaagacggagagc
tcgtcgtacttccgccggaaggagaagatgctgcggttcctggtgcggcgagtggtgaag
gcgcagagcttctactgggcagtgctgtgcgtggtggcgctgaacacgctgtgcgtggcc
atggtgcaccacaaccagccccagcggctcaccacggcgctgtactttgcagagtttgtt
ttcctgggtctcttcctcacagagatgtccctgaagatgtatggcctggggccccggagc
tacttccggtcctccttcaattgcttcgacttcggggtcatcgtggggagcatcttcgaa
gtggtgtgggctgccatcaagccaggaacctcctttgggatcagtgttctgcgggcactc
cggttgctgaggatcttcaaagtcacaaagtactggaactccctgcggaacctggtggtg
tccctgctcaactccatgaagtccatcatcagcctgctcttcttgctcttcctcttcatc
gtggtcttcgccctgctgggcatgcagctgttcgggggacagttcaactttaaagatgag
acgccaaccaccaactttgacaccttccctgccgccatcctcactgtgttccagatcctg
accggggaggactggaatgctgtgatgtaccacgggatcgagtcgcagggtggcgtcagc
aaaggcatgttctcgtcctgctatttcatcgtcctgacgctgttcgggaactacaccttg
ctgaatgtcttcctggccatcgccgtggacaacctcgccaacgcccaggagctgaccaag
gatgaagaggagatggaggaggcggccaaccagaagctcgccctgcagaaggccaaggag
gtggctgaagtcagccctgtgtcggccgccaacgtctccgtcgctgccaggcagcagagc
tcggccaaggcgcgctcggtgtgggagcagcgggccagccagctgcggctgcagaacctg
cgggccagctgcgaggcgctgtacagcgagctggaccccgaggagcgcctgcgctacgcc
accacgcgccacctgcggcccgacatgaagacgcacctggaccggccgctggtggtggag
cccagcaggaatggcccgcgggggccggccgcaggcaaggcccagcccgagggcgcagag
gccaccgagggcacggacccgccacgcaggcaccaccggcaccgcgacaaggacaaggcc
ccggccccggctgctggggagcccgagcgggcggacgccccaaaggcggagggcggggag
ccggtggcccgggaagagcgagtgcggccgcaccgcagccgcaacaaggaggtccgcagc
ggccgcggccgcggcccggggcctgagggcggccggcgccaccaccggcacgggtccccg
gaggaggcggccgaacgggaaccccggcgccaccgcacccaccggcacgcgcccgaccag
ggcaaagagggcagcgcacctggggccaagggcgagcggcgggcacggcaccgcggcggc
acccgggctggtgcccgggagcccgagagcatggaggagccggcacggcggcaccgggca
cggcacagggcgccacccacacacgaggacgcggagaaggaggcagaggagaaggagggc
gagacccaggacagggacagggacaaggaagtccggaaccaccagcccaaggagccacgt
ggggacctgggggacggcggggtgacggctgtgggccctgtgcacacgctgcccagcacc
tgtctacagaaggtggaggagcagccggaggacgcggataaccagcggaacgtcactcgg
atgggcagccagcccgcagaccccggtgcccctgtgcacatcccggcggcgccgaccggg
ccccccgccgagggcaccgttgtccccagtggcagcggggacctggaaagccaagcagat
gggaggaaggcggcggaggccgaggacgtgacgaggagcggcccccggcccatcgtcccc
tacagctccatgttctgcctgagccccactgccctgctccgccgttgctgccactacatc
gtgaccatgaggtacttcgagatggtcatccttgtggtcatcgccctgagcagcatcgct
ctggccgcagaggaccccgtgcggacagactcgcccaggaacaacgccctgaaatacttg
gactacatcttcacgggcgtcttcacctttgagatggtgatcaagatgattgatctgggg
ctgctgctgcatcccggggcctacttccgggacctgtggaatattctggacttcattgtg
gtcagtggggccctggtggcgtttgccttctcgggctccaaagggaaagacatcaacacc
atcaagtccctgagggtcctgcgtgtcctgcggccgctcaagaccatcaagcggctgccc
aagctcaaggccgtgttcgactgcgtggtgaactccctgcgcaacgtgctcaacatcctg
gtcgtctacgtgctcttcatgttcatcttcgccgtcatcgccgtgcagctgttcaagggc
aagttcttctactgcacggacgagtccaaggagcgggagcgggactgccggggccagtat
ctggactacgagaaggaggaagtggaggcccagcctcggcagtggaagaagtacgacttc
cactacgacaacgtgctctgggcactgctgacgctcttcaccgtgtccactggcgaaggg
tggcccatggtgctgaaacactccgtggatgccacctacgaggagcagggcccaagccct
gggtaccgcatggagctgtccatcttctacgtggtctacttcgtggtctttcccttcttc
tttgtcaacatcttcgtggccttgatcatcatcaccttccaggagcagggggacaaggtg
atgtcagaatgtagcctggagaaaaacgagagggcttgcatcgacttcgccatcagcgcc
agacccctgacgcggtacatgccacgggacaagcagtcgctgcagtacaagacgtggacg
ttcgtggtgtctccacccttcgagtacttcatcatggccatgatagccctcaacacgctg
gtgctgatgatgaagttctacggcgcgccctacgagtacgagctgctgctgaagggcctg
aacgtggccttcacctctgtgttctccatggagtgcctgctgaagatcgtcgcgttcggg
gtgctgaactacttcagagatgcttggaatgtgtttgactttgtcactgtgctgggaagt
attactgatattttagtgacagaaattgcggaaacgaacaacttcatcaacctgagcttc
ctgcgcctgttccgcgcggcgcggctcatcaagctgctgcgccagggctacaccatccgc
atcctgctgtggaccttcgtgcagtccttcaaggccctgccctacgtgtgcctgctcatc
gccatgctcttcttcatctacgccatcatcggcatgcaggtgttcgggaacatcgccctg
gacgatgactccagcatcaacagacacaacaacttccggacgtttctacaggccttgatg
ctgctgttcaggagcgccacgggggaggcctggcacgagatcatgctgtcctgcctcagc
gaccgggcctgcgacgagcatgccagcgccagcgcctgcggcagcgacttcgcctacttc
tacttcgtgtccttcatcttcctgtgctccttcctgatgctgaacctcttcgtggccgtg
atcatggacaacttcgagtacctcacacgggactcgtccatcctggggccacaccacctg
gacgagttcatccgagtgtgggccgagtacgacccggccgcgtgcgggcgcatcagttac
agtgacatgtttgagatgctgaagcacatgtccccgcccctggggctggggaagaagtgc
ccggctcgagttgcctacaagcgcctggtccgcatgaacatgcccatctccagcgaggac
atgaccgtccacttcacgtccacactgatggccctcatccggaccgcgctagagatcaag
ctggctccagccggcaccacgcagcaccagtgcgacgcagagctgaggaaggagatctcc
tccgtgtgggccaaccttccccagaagactctggatttgctggtgccaccccataaaccc
gacgaggtgacggtggggaaagtctacgccgccctgatgatcttcgacttctacaaacag
agcaaaagcagcagggaccagactcaccaagccccgggaggcctgacccagatgggtccc
gtgtccctgtttcaccctctgaaggccacgctggagcagacacagccggctgtgctccga
ggggcccgggttttccttcagcagaagagctcgacctctctcagcaatggcggggcggta
caaacccaagagagtggcatcaaggagtctgtttcctggggcacccaaaggacccaggac
atgctctgtgagtcaaggaggcccctagagcgtggccactcgacagagatcccagtggtg
cagcccggaaaaccagctgcggatgtccagacgcagagcatggccctgaggggccctgac
ggggagccccagcccgggctggagagccagggccgtgcggcctccatgccccgcctggca
gcagagacacagccggcccccggcgccagccccatgaagcgctcggtgtccacgctggcg
ccgcagcgcccccgcgcggccccgctgtgcaacgccgccccggaccgcgcccccgccggc
ccggccgccgcgcaccaccaccaccgctgccaccgccgcagggacaggaagcagaagtcc
ctggagaaggggcccagcctgtccgcggacacggatggcgccccccacagcgcggggccg
gggccgcccccggcggaggggcccgcaggcggccggcgggagcgcaggcaggagcgcggc
cggtcccaggagcgcaggcagccgtcgtcgtcgtcctccgagaagcagcgcttctactcg
tgcgaccgcttcgggggccgcgagcccccgcacccccggccctccctcagcagccacccc
acctcgcccacggccgggcaggagccaggacccctgaggcagggtggcggctcggcaaac
gggagccccttgctgtcagcatccggtgctagcacccctggccgtggcgggcggaggcag
ctcccccagaccccattgacgccccggcccagcgtcacctacaagacggcgcactcctcg
cctgtgcacttcgcgggggctcagaccagcctcccggccttctcccccggccggctgagc
cgaggcctttccgaacacaacgccttgctccagagagaccccctcagccagcccctggcc
cccagctctcggactggctctgacccttacctggggcagcgtcttgacggtgagaccacg
gcccgcacccagcccgaggacgcactcaccttcgaggaggccgtggccaccaactccggc
cgctcctcccggacttcctacgtgtcctccctgacttcgcagccccatcccccccgccgc
gtgcccaacgggtaccactgcaccctgggcccgggccccggcagccgagcacgtctcagt
gcccaccaccccgaccgggaccactggtgctag

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