Rousettus aegyptiacus (Egyptian rousette): 107509347
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Entry
107509347 CDS
T06036
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521
EGFR tyrosine kinase inhibitor resistance
ray01522
Endocrine resistance
ray04010
MAPK signaling pathway
ray04014
Ras signaling pathway
ray04015
Rap1 signaling pathway
ray04066
HIF-1 signaling pathway
ray04068
FoxO signaling pathway
ray04081
Hormone signaling
ray04114
Oocyte meiosis
ray04140
Autophagy - animal
ray04144
Endocytosis
ray04150
mTOR signaling pathway
ray04151
PI3K-Akt signaling pathway
ray04152
AMPK signaling pathway
ray04211
Longevity regulating pathway
ray04213
Longevity regulating pathway - multiple species
ray04510
Focal adhesion
ray04518
Integrin signaling
ray04519
Cadherin signaling
ray04520
Adherens junction
ray04550
Signaling pathways regulating pluripotency of stem cells
ray04730
Long-term depression
ray04913
Ovarian steroidogenesis
ray04914
Progesterone-mediated oocyte maturation
ray05200
Pathways in cancer
ray05202
Transcriptional misregulation in cancer
ray05205
Proteoglycans in cancer
ray05214
Glioma
ray05215
Prostate cancer
ray05218
Melanoma
ray05224
Breast cancer
ray05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107509347 (IGF1R)
04014 Ras signaling pathway
107509347 (IGF1R)
04015 Rap1 signaling pathway
107509347 (IGF1R)
04066 HIF-1 signaling pathway
107509347 (IGF1R)
04068 FoxO signaling pathway
107509347 (IGF1R)
04151 PI3K-Akt signaling pathway
107509347 (IGF1R)
04152 AMPK signaling pathway
107509347 (IGF1R)
04150 mTOR signaling pathway
107509347 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
107509347 (IGF1R)
04518 Integrin signaling
107509347 (IGF1R)
04519 Cadherin signaling
107509347 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
107509347 (IGF1R)
04140 Autophagy - animal
107509347 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
107509347 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
107509347 (IGF1R)
04520 Adherens junction
107509347 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
107509347 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
107509347 (IGF1R)
04914 Progesterone-mediated oocyte maturation
107509347 (IGF1R)
09156 Nervous system
04730 Long-term depression
107509347 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
107509347 (IGF1R)
04213 Longevity regulating pathway - multiple species
107509347 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107509347 (IGF1R)
05202 Transcriptional misregulation in cancer
107509347 (IGF1R)
05205 Proteoglycans in cancer
107509347 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
107509347 (IGF1R)
05214 Glioma
107509347 (IGF1R)
05218 Melanoma
107509347 (IGF1R)
05215 Prostate cancer
107509347 (IGF1R)
05224 Breast cancer
107509347 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107509347 (IGF1R)
01522 Endocrine resistance
107509347 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ray01001
]
107509347 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ray04090
]
107509347 (IGF1R)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
107509347 (IGF1R)
Protein kinases [BR:
ray01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
107509347 (IGF1R)
CD molecules [BR:
ray04090
]
Proteins
107509347 (IGF1R)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Fn3_Dep-1_6th
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
107509347
NCBI-ProteinID:
XP_036087913
LinkDB
All DBs
Position
Unknown
AA seq
1399 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFCVALSLWPVSGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLHNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYVVGNKPQKECGD
LCPGAMEAKPLCEKTTINNEYNYRCWTNSHCQKMCPSACGKRACTEDNECCHPECLGGCS
APDDDAACVACRHYYFSGVCVTSCPPNTYRFEGWRCVDRDFCANIPNADGNDVEGFVIHD
GECMQECPSGFIRNGSQSMFCIPCEGPCPKVCEEDKKTKTIDSVTSAQMLQGCTIFRGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQGKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPSNKDIEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPVRKYADGTFEIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVSQVANTTMSSRGRNSTADAYNGTDLDEPESEFPFYESR
VDNKERTVISNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWE
PRPENSIFLKWPEPENPNGLILMYEIKYGSQLEDQRECVSRQEYRKHGGAKLNRLNPGNY
TARIQATSLSGNGSWTEPVFFYVQAKTTYENFTHLVIALPVAILLIVAGLVIMLYVFHRK
RNSNRLGNGVLYASVNPEYFSAADVYVPDEWEVARDKITMNRELGQGSFGMVYEGVAKGV
VKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMEL
MTRGDLKSYLRSMRPEVEAHRVGAGEVTHGTCHSKRAFQRSKRRRVAKKTENNVVLIPPS
LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRK
GGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGFSNEQVLRFVMEG
GLLDKPDNCPDIMFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPGFQEVSFYYSDENKPP
DMEELDLEPENMESIPLDPSASSLSLPLPDRLSGHRMENGPGPGMLVLRASFDDRQPYAH
MNGGRKNERPLPLPQSSTC
NT seq
4200 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctgc
gtcgcgctctcgctgtggccggtgagcggagaaatctgcgggcccggcatcgacatccgc
aatgactaccagcagctgaggcgcctggagaactgcacggtgatcgagggttacctgcac
atcctgctcatctccaaggccgaggactaccggagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggcgacctcttc
ccgaacctcacggtcatccgcggatggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatagggcttcacaatctgcggaacatcacccgtggggcc
atcaggatcgagaagaacgctgacctctgctacctgtccacagtagactggtccctgatc
ctggacgccgtctccaacaactacgtcgtggggaacaaaccccaaaaggagtgtggggac
ctgtgtccaggggcgatggaggcgaagccgctgtgcgagaagaccaccatcaacaacgag
tacaactaccggtgctggaccaacagccactgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcaccgaggacaacgagtgctgccaccccgagtgcctgggcggctgcagc
gcgcccgacgacgacgcggcctgcgtggcctgtcgccactactacttctccggcgtgtgc
gtgacctcctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccaacgccgacggcaacgacgtggagggcttcgtcatccacgac
ggcgagtgcatgcaagagtgcccctcgggcttcatccgcaacggcagccagagcatgttc
tgcatcccttgcgaaggaccttgccccaaagtctgtgaggaagataagaaaacgaagacc
attgattcggttacttctgctcagatgctccaaggatgcaccatattcaggggcaatttg
ctcattaatattcgaagaggcaataacattgcctcggagctggagaacttcatggggctt
atcgaggtggtgacgggctacgtgaagatccgccactcccacgccttggtgtccttgtcc
ttcctgaaaaaccttcgccagatcctaggagaggagcagctggaggggaactactccttc
tacgtcctcgacaaccagaacctgcagcagctgtgggactgggaccaccggaacctcacc
atcaaggccgggaagatgtacttcgccttcaaccccaagctgtgcgtctccgagatctac
cgcatggaggaggtgaccgggaccaaaggccgccagggcaaaggggacataaacaccagg
aacaacggagagagagcctcctgtgagagcgacgtcctgcacttcacctccaccaccacg
tggaagaaccgcatcatcatcacatggcaccggtaccggccgccggactacagggacctc
atcagcttcaccgtctactacaaggaagcaccctttaaaaacgtgacggaatatgacggg
caggacgcctgcggctccaacagctggaacatggtggatgtggacctgccttccaacaag
gacatcgagcccggcatcctgctgcacggcctgaagccctggacgcagtacgccgtgtac
gtcaaggccgtgaccctgaccatggtggagaacgaccacatccgcggggccaagagtgaa
atcctgtacatccgcacgaacgcgtcagttccttccattcccctggacgtcctgtccgcc
tcgaactcctcttcccagctgatcgtgaagtggaacccgccctccctgcccaacggcaac
ctgagctactacattgtgaggtggcagcgacagcctcaggacggctacctgtaccggcac
aattactgctccaaagacaaaatccccgtcaggaagtacgccgacggcaccttcgagatc
gaggaggtgacggagaaccccaagaccgaggtgtgcggtggcgagaaggggccttgctgc
gcgtgccccaaaaccgaagccgagaagcaggcggagaaggaggaggccgagtaccgcaaa
gtgttcgagaacttcctgcacaactccatcttcgtgcccagacccgagcggaagcggaga
gacgtctcgcaggtggccaacaccaccatgtccagccgaggcaggaacagcacggcggac
gcctacaacggcacggacctggacgagccggagtccgagttccctttctacgagagcaga
gtggacaacaaggagaggacggtcatctccaacctgcagcccttcactctgtaccgcatc
gacatccacagctgcaaccacgaggcggagaagctgggctgcagcgcctccaacttcgtg
tttgcgaggaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgggag
ccacggccggaaaactccatctttttaaagtggccggaacctgagaatcccaatggatta
attctaatgtatgaaataaaatacggatcacaactcgaggaccagcgggaatgcgtgtcc
aggcaggaataccggaagcacggaggggccaagctgaaccggctcaacccgggcaactac
acggcccgcatccaggccacctctctgtccggaaacgggtcgtggacggagccggtgttc
ttctacgtccaggccaaaacgacctatgaaaatttcacgcatctggtgatcgccctgccc
gttgccatcctgctgatagtggcggggctggtgataatgttgtatgtcttccaccggaaa
agaaacagtaacagactgggcaatggagtgctgtatgcatctgttaaccctgaatacttc
agcgcggctgacgtgtacgtgcccgacgagtgggaggtggcccgcgacaagatcaccatg
aaccgggagctgggccagggctccttcgggatggtgtacgagggcgtggccaagggcgtc
gtcaaggacgagcccgaaaccagagtggccattaaaacggtgaacgaggcggcgagcatg
cgcgagaggatcgagtttctgaacgaggcttcggtgatgaaggagttcaactgtcaccat
gtggtgcggctgctgggtgtggtgtcccagggccagccgacgctggtcatcatggaactg
atgacccggggcgatctcaagagttatctccggtccatgaggcctgaagtggaggcccac
agggttggagctggagaggtgacacatgggacctgtcacagcaagagggcttttcagcgt
tctaagagacgccgtgtggccaagaaaactgagaataatgtggtgctcatccctccaagc
ctgagcaagatgatccagatggcaggagagatcgcggacggcatggcgtacctcaacgcc
aacaagttcgtgcacagggacctggccgcccgcaactgcatggtggccgaggatttcacc
gtcaaaatcggagatttcggaatgaccagagacatctacgagaccgactattaccggaag
ggagggaaaggcctgctgcccgtgcgctggatgtcccccgagtccctgaaggacggcgtc
ttcaccactcactctgatgtctggtccttcggcgtcgtcctctgggagatcgccacgctg
gccgagcagccgtaccagggcttctccaacgaacaggtcctgcgcttcgtcatggagggc
ggcctgctggacaaaccggacaactgccccgacataatgttcgagctgatgcgcatgtgc
tggcagtacaaccccaagatgcggccttccttcctggagatcatcggcagcatcaaggac
gagatggagcccggcttccaggaggtgtccttctactacagcgacgagaacaagccgccc
gacatggaggagctggacctggagccggagaacatggagagcatcccgctggacccctcg
gcctcgtcgctgtccctgccgctgcccgacagactctcaggacaccggatggagaacggc
ccgggcccgggcatgctggtcctccgggccagcttcgacgacaggcagccttacgcgcac
atgaatgggggacgcaagaatgagaggccactgcctctcccccagtcctccacctgctga
DBGET
integrated database retrieval system
