Rousettus aegyptiacus (Egyptian rousette): 107511436
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Entry
107511436 CDS
T06036
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521
EGFR tyrosine kinase inhibitor resistance
ray01522
Endocrine resistance
ray04010
MAPK signaling pathway
ray04012
ErbB signaling pathway
ray04014
Ras signaling pathway
ray04062
Chemokine signaling pathway
ray04068
FoxO signaling pathway
ray04072
Phospholipase D signaling pathway
ray04150
mTOR signaling pathway
ray04151
PI3K-Akt signaling pathway
ray04510
Focal adhesion
ray04540
Gap junction
ray04630
JAK-STAT signaling pathway
ray04650
Natural killer cell mediated cytotoxicity
ray04660
T cell receptor signaling pathway
ray04662
B cell receptor signaling pathway
ray04664
Fc epsilon RI signaling pathway
ray04714
Thermogenesis
ray04722
Neurotrophin signaling pathway
ray04810
Regulation of actin cytoskeleton
ray04910
Insulin signaling pathway
ray04912
GnRH signaling pathway
ray04915
Estrogen signaling pathway
ray04917
Prolactin signaling pathway
ray04926
Relaxin signaling pathway
ray04935
Growth hormone synthesis, secretion and action
ray05034
Alcoholism
ray05160
Hepatitis C
ray05161
Hepatitis B
ray05163
Human cytomegalovirus infection
ray05165
Human papillomavirus infection
ray05200
Pathways in cancer
ray05205
Proteoglycans in cancer
ray05206
MicroRNAs in cancer
ray05207
Chemical carcinogenesis - receptor activation
ray05208
Chemical carcinogenesis - reactive oxygen species
ray05210
Colorectal cancer
ray05211
Renal cell carcinoma
ray05213
Endometrial cancer
ray05214
Glioma
ray05215
Prostate cancer
ray05220
Chronic myeloid leukemia
ray05221
Acute myeloid leukemia
ray05223
Non-small cell lung cancer
ray05224
Breast cancer
ray05225
Hepatocellular carcinoma
ray05226
Gastric cancer
ray05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107511436 (SOS2)
04012 ErbB signaling pathway
107511436 (SOS2)
04014 Ras signaling pathway
107511436 (SOS2)
04630 JAK-STAT signaling pathway
107511436 (SOS2)
04068 FoxO signaling pathway
107511436 (SOS2)
04072 Phospholipase D signaling pathway
107511436 (SOS2)
04151 PI3K-Akt signaling pathway
107511436 (SOS2)
04150 mTOR signaling pathway
107511436 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
107511436 (SOS2)
04540 Gap junction
107511436 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
107511436 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
107511436 (SOS2)
04660 T cell receptor signaling pathway
107511436 (SOS2)
04662 B cell receptor signaling pathway
107511436 (SOS2)
04664 Fc epsilon RI signaling pathway
107511436 (SOS2)
04062 Chemokine signaling pathway
107511436 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
107511436 (SOS2)
04912 GnRH signaling pathway
107511436 (SOS2)
04915 Estrogen signaling pathway
107511436 (SOS2)
04917 Prolactin signaling pathway
107511436 (SOS2)
04926 Relaxin signaling pathway
107511436 (SOS2)
04935 Growth hormone synthesis, secretion and action
107511436 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
107511436 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
107511436 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107511436 (SOS2)
05206 MicroRNAs in cancer
107511436 (SOS2)
05205 Proteoglycans in cancer
107511436 (SOS2)
05207 Chemical carcinogenesis - receptor activation
107511436 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
107511436 (SOS2)
05231 Choline metabolism in cancer
107511436 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
107511436 (SOS2)
05225 Hepatocellular carcinoma
107511436 (SOS2)
05226 Gastric cancer
107511436 (SOS2)
05214 Glioma
107511436 (SOS2)
05221 Acute myeloid leukemia
107511436 (SOS2)
05220 Chronic myeloid leukemia
107511436 (SOS2)
05211 Renal cell carcinoma
107511436 (SOS2)
05215 Prostate cancer
107511436 (SOS2)
05213 Endometrial cancer
107511436 (SOS2)
05224 Breast cancer
107511436 (SOS2)
05223 Non-small cell lung cancer
107511436 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
107511436 (SOS2)
05160 Hepatitis C
107511436 (SOS2)
05163 Human cytomegalovirus infection
107511436 (SOS2)
05165 Human papillomavirus infection
107511436 (SOS2)
09165 Substance dependence
05034 Alcoholism
107511436 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107511436 (SOS2)
01522 Endocrine resistance
107511436 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
PH_19
RHG20_PH
PH_10
PH_13
Motif
Other DBs
NCBI-GeneID:
107511436
NCBI-ProteinID:
XP_016001254
UniProt:
A0A7J8IU18
LinkDB
All DBs
Position
Unknown
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPSLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPTSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKPSDI
EKIFSNISDIHELTIKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQAIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYAPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCEYKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIRRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTSPNSPN
TPPSTPSPRVPRRSYVLNSSQNNLAHPQAPPVPPRQTSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttagtctcggccctgcggaaggttcaggagcaagtacatcccagtctctcagct
aatgaagaatctctgtattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaaaacctttcctcat
ccaattgataaatgggctattgctgatgcacagtctgctatagagaaacgcaaacgaaga
aatcctctcttgttgcctgtggacaaaatccatccttcactgaaggaagttttagggtac
aaagtggactaccatgtgtctttatatattgtggctgtactagagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctttgtgaagatgaacctacttcttcaggtgaattaaactactat
gatcttgtcagaactgaaattgcagaagaaagacagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttctgacaaaaagctgtttaaaccttctgacatt
gaaaagattttcagtaatatctcggatatacacgagttgactataaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcacctaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctctt
cactttcaggccattgctgatggttttaaagaagcagttcgttatgtccttccacgcctt
atgctggtgccagtgtatcactgttggcactattttgaattattgaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcagtatgcaccacgacgccgacctggggat
cctgtttgccctttttataatcgccaattaagaagcaagcatctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacaagaattggtgctaaacatgaacggcatattttt
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccaggt
tacagtagtgcagaatacagattaaaagaaaaatttgttatgaggaaaatacaaatatgt
gataaagaagatacttgtgagtacaaacatgcttttgagttagtatccaaagatgaaaac
agtataatatttgcagctaagtctgctgaagagaaaaacaattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgctagattcagtattattgaaagaagaa
aatgaacaacctttgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaagattaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgctaagc
ttactaattgaacgatttgaaattccggagccggaacctactgaagcagataaattggct
gtagagaaaggcgagcagccaattagtgcagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttagaatcttaaatgtttttcggcactgggttgaacaccatttttat
gactttgaaagagatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagccatgaagaaatgggtagagtccattgctaagatcatcaggaggaagaaacaa
gctcaggcaaatggaataagccacaatattacctttgaaagtccacctccaccaattgaa
tggcatatcagcagaccaggacagtttgaaacatttgatcttatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctttacaggaaagtacaaccctct
gaacttgtaggaagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccacactacaaatcttacgctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgagtggcagtactgagtagaattatagaaattctgcaagtcttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccatacatttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattgagtcaagaccactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagacttaatcaatttcagtaagaggagg
aaagtggctgaaattactggagaaattcagcagtatcagaatcaaccttattgtttacgg
atagaaccagaaatgaggcgattctttgaaaatcttaaccccatgggaagtgcttctgaa
aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttgaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacaccattggaa
agagaaccatgtaaaataagctttagtcggattgctgaaactgagcttgaatcaacagtg
tcagcaccgacctctccaaacacaccatctactccaccggtatctgcttcttcagacctc
agtgtgtttttagatgtggatctcaatagttcctgtggcagcaatagcatcttcgctcca
gttctcttgccacattcaaagtctttcttcagttcgtgtggtagtttacataaacttagt
gaagagccactgattcctccacctcttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatatgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgatgggcctctg
catagtccacctccaccgccgccaagagatcctcttcctgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccatttaatcttcagccacctccgctggga
catcttcacagagatccagactggttcagagatgttagtacgtctccgaattcgccaaac
actcctcctagcacaccttctccaagggtgccacgtcgaagctatgtgctcaattctagt
cagaataatcttgctcatcctcaagctccccctgttccaccaaggcagacttcaagccct
cacctcccaaaactgccaccaaagacttacaaacgggagctttcacaccccccattgtat
agactgcctttgctagaaaatgcagaaactcctcaatga
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integrated database retrieval system
