Rousettus aegyptiacus (Egyptian rousette): 107511924
Help
Entry
107511924 CDS
T06036
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00010
Glycolysis / Gluconeogenesis
ray00020
Citrate cycle (TCA cycle)
ray00620
Pyruvate metabolism
ray00785
Lipoic acid metabolism
ray01100
Metabolic pathways
ray01200
Carbon metabolism
ray01210
2-Oxocarboxylic acid metabolism
ray04066
HIF-1 signaling pathway
ray04922
Glucagon signaling pathway
ray05230
Central carbon metabolism in cancer
ray05415
Diabetic cardiomyopathy
Module
ray_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
107511924 (PDHA1)
00020 Citrate cycle (TCA cycle)
107511924 (PDHA1)
00620 Pyruvate metabolism
107511924 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
107511924 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
107511924 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
107511924 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
107511924 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107511924 (PDHA1)
Enzymes [BR:
ray01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
107511924 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
107511924
NCBI-ProteinID:
XP_016002372
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILTELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATSDPEPP
LEELGYHIYSNDPPFEVRGANQWVKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgccgcccagaagccggca
agcagagtgctggtggcatcccgaaattttgcaaacgatgctacatttgaaattaagaaa
tgtgatcttcaccggctggaagagggccctcctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgttcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaatcattcgtggtttctgtcacttgtgtgatggtcaagaagcttgt
tgtgtgggcctggaggctggcataaatcccacagatcatctgatcacagcctatcgggct
catggctttacctttactcgtgggctttctgtccgagaaattctcacagagcttacaggg
cgaagaggaggttgtgctaaaggaaaaggtggatcaatgcatatgtatgccaagaacttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagctgggattgctctggcc
tgtaagtataatggaaaagatgaagtctgtttgactttatatggcgatggtgctgctaat
cagggtcagatattcgaagcttacaatatggcagccttgtggaaattaccttgtattttc
atctgtgaaaataaccgctatggaatgggaacatctgttgagagagcagcagccagcact
gattactataagagaggtgacttcattcctgggctgagggtagatggaatggatgtcctg
tgtgtccgggaggcaacgaagtttgcagctgcccattgtagatctggaaaggggcccata
ctgatggagctgcagacttaccgttaccatgggcacagcatgagtgatcccggagtcagt
tatcgtacacgagaagaaattcaggaagtaagaagtaagagcgaccctatcatgcttctc
aaggatagaatggtgaacaacaatcttgccagtgttgaagaattaaaggaaattgacgtt
gaagtaaggaaagaaattgaagatgccgcccagtttgccacatccgatcctgaaccacct
ttggaagaactaggctatcacatctactccaatgatccaccttttgaagttcggggtgca
aatcagtgggtcaagtttaagtccgtcagttaa
DBGET
integrated database retrieval system
