Rousettus aegyptiacus (Egyptian rousette): 107513400
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Entry
107513400 CDS
T06036
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00230
Purine metabolism
ray00670
One carbon pool by folate
ray01100
Metabolic pathways
ray01523
Antifolate resistance
Module
ray_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107513400 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
107513400 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
107513400 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ray04147
]
107513400 (ATIC)
Enzymes [BR:
ray01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
107513400 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
107513400 (ATIC)
Exosome [BR:
ray04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
107513400 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
107513400
NCBI-ProteinID:
XP_016005542
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPGQLALFSVSDKTGLVEFAKNLTSFGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVAFPDVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVSTEMQSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELRESLGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVHDMYRTLTPIS
TAYARARGADRMSSFGDFVALSDICDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNG
NYCVLQMDPSYNPDENEVRTLFGLRLSQKRNTGVVDRSLFSNVVTKNKDLPESAIRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANFWWLRHHPRVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLVKWKALFEEVPELLTETEKKEWIDKLSDVSISSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADAVVTEACNELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgctttgtttagtgtctctgacaaaaccggccttgtggaattt
gccaaaaacctgacttcctttggtttgaatctgatagcttctggagggacagcaaaagct
ctcagggatgctggtctggcagtcagagatgtctctgagctgacaggatttcccgaaatg
ttagggggacgtgtgaaaaccctgcatcctgcagtccatgctggtatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgttgtt
tgtaatctgtatccctttgtgaagacagtggcttttccagatgtaactgttgaagaggct
gttgagcaaattgatattggtggagtaaccctgctgagagcagcagccaaaaaccatgct
cgagtgacagtagtgtgtgaaccagaggactatgcagccgtgtccacagagatgcagagc
tcggacagtaaagacacctccctggagaccagacgccagttagccttgaaggctttcact
cacacggcacagtatgacgaagcaatttcagattacttcaggaaacagtatagtaaagga
atatctcagatgcccttgaggtatggaatgaacccacatcaaactcctgcccagttatac
acactgaagcccaagcttcccattacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaaagtttaggcatccca
gctgctgcctctttcaagcacgtcagcccagcaggtgctgctgttggaatcccacttagt
gaagacgaggccaaagtttgtatggtccatgacatgtacagaaccctgacacccatatca
actgcatatgcacgagcaagaggggctgataggatgtcttcatttggtgactttgttgca
ttatctgatatatgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgaagaagaagctttgaaaattctctctaaaaagaaaaatggg
aactactgtgttcttcagatggatccatcttacaatcccgatgagaatgaagttcgaact
ctctttggtcttcgtttaagccagaagagaaatactggtgtcgtcgacaggtcattattt
agcaatgttgttaccaagaataaagatttgccagaatctgcgatcagagatctcattgtg
gccaccattgctgtcaagtacacccagtctaactccgtgtgctatgccaagaacggccag
gtcattggcattggagcaggacagcagtctcggatacactgcacacgccttgcaggagat
aaggcgaacttttggtggcttagacatcacccacgagtactctcaatgaagtttaaaacc
ggagtgaagagagcagaaatctccaatgccatcgatcagtatgttactggaaccattggc
gaggatgaagatttagtaaagtggaaggcactgtttgaggaggttcctgaattactaact
gagacagagaagaaggaatggattgacaaactcagtgacgtttccatcagctccgatgcc
ttctttcctttcagggataacgtagacagagctaaaaggagtggcgtggcgtacattgct
gccccttccggttctgctgccgatgccgtcgtgaccgaggcttgcaatgagctgggaata
atcctcgctcatacgaatcttcgtctctttcatcactga
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