Rousettus aegyptiacus (Egyptian rousette): 107514157
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Entry
107514157 CDS
T06036
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00020
Citrate cycle (TCA cycle)
ray00480
Glutathione metabolism
ray01100
Metabolic pathways
ray01200
Carbon metabolism
ray01210
2-Oxocarboxylic acid metabolism
ray01230
Biosynthesis of amino acids
ray04146
Peroxisome
ray05230
Central carbon metabolism in cancer
Module
ray_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ray_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
107514157 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
107514157 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
107514157 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
107514157 (IDH2)
Enzymes [BR:
ray01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
107514157 (IDH2)
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Ortholog
Paralog
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
107514157
NCBI-ProteinID:
XP_016007076
UniProt:
A0A7J8CGV1
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All DBs
Position
Unknown
AA seq
450 aa
AA seq
DB search
MAGYLRVVRSLGRASGSGPAWAPAALTGPNLQDQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPHRDKTDDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKMVFTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFSQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTTDFLDTIKNNLDKALG
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atggctggctacctgcgggtcgtacgctcgctcggcagagcctcgggctccggcccggcc
tgggcgccggcagccctgacaggccccaacttgcaggaccagccgcggcgccactatgct
gacaagaggatcaaggtggccaagccggtggtggagatggacggcgatgagatgacccgc
atcatctggcagttcatcaaggagaagctcatcttgccccacgtggacgtccagctcaag
tattttgacctggggctcccacaccgtgacaagactgatgaccaggtcaccattgactct
gcattggccacccagaaatacagtgtagctgtgaagtgtgccaccatcacccctgatgaa
gcccgcgtggaagagttcaagctgaagaagatgtggaagagtcctaatgggaccatccgg
aacatcctgggcggaaccgtcttccgggagcccatcatatgcaaaaacatcccccgcctc
gtccctggctggaccaagcccatcaccattggcaggcacgcccacggcgaccagtataag
gccacagactttgtggccgaccgggctggcacgttcaagatggtcttcaccccgaaggat
ggtagcagcgcaaaggagtgggaggtgtacaacttccctgctggtggcgtgggcatgggc
atgtacaacacggatgagtccatctcaggttttgcgcacagctgcttccaatatgccatc
cagaagaagtggccgctgtacatgagcacgaagaacaccattctgaaagcctacgacggc
cgcttcaaggacatcttccaggagatctttgacaagcattataagaccgactttgacaag
aataagatctggtatgagcaccggctcattgatgacatggtggctcaggtcctcaagtct
tcaggtggctttgtgtgggcctgcaagaactacgacggagacgtgcagtcggacatcctg
gcccagggctttggttccctcggcttgatgacgtccgtgctggtctgcccggatgggaag
accatcgaggctgaggctgctcatgggacagtcacgcgtcattatcgggagcaccagaag
ggccggcctaccagcaccaaccccatcgccagcatctttgcctggacacgtggcctggag
caccgggggaagctggacgggaaccaggacctcatcaggttttcccagaccctggagaag
gtgtgcgttcagaccgtggagagcggagccatgaccaaggacctggcgggctgcatccat
ggcctcagcaacgtgaagctgaacgagcacttcctgaacaccacggacttcctggacacc
atcaagaacaatctggacaaggccctgggctag
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