KEGG   Rousettus aegyptiacus (Egyptian rousette): 107514664
Entry
107514664         CDS       T06036                                 
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A isoform X1
  KO
K13298  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00230  Purine metabolism
ray01100  Metabolic pathways
ray04934  Cushing syndrome
ray05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:ray00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    107514664 (PDE11A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    107514664 (PDE11A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107514664 (PDE11A)
Enzymes [BR:ray01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     107514664 (PDE11A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     107514664 (PDE11A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 HD-CE HD
Other DBs
NCBI-GeneID: 107514664
NCBI-ProteinID: XP_016008082
LinkDB
Position
Unknown
AA seq 950 aa
MTASHLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQRQGALGPRLALPGTSS
LAHVDGRGSSSVGGGTGSNGSGNSQPTLGGGDCGGVPLSPSWASGNRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKFID
YLPRYRIWLLITCKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDL
EKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKESMEK
SSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQ
IIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSY
HATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKID
YETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLC
HDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSD
LMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKP
WEISRQVAELVTSEFFEQGDRERAELKLIPSAIFDRNRKDELPRLQLEWIDSICMPLYQA
LVKVNAKLKPMVDSVAANRSKWEELHRKRLLVSAASPSSASLLVAGADSN
NT seq 2853 nt   +upstreamnt  +downstreamnt
atgacagcttcccacctggactttggggaggtggaaactttcctggacaggcacccagag
ttgtttgaagattatttgatgcggaaggggaagcaggagatggtggagaagtggctgcag
aggcacagtcagaggcagggggctttaggcccaaggctggcactgcctggcaccagcagc
ttggctcacgtcgatggcagaggcagcagcagcgttggtggtggcactggatcaaatggc
tctggcaacagccagcccactctgggtggcggggactgtggtggggtacccctgagtccc
agctgggccagtggcaaccggggtgatgggaacctgcagcgaagagcttctcagaaagag
ctaaggaagagttttgcccgctccaaagccatccacgtgaacaggacctatgatgaacaa
gtgacctcccgggcccaggagcccctgagcagtgtgcggcggagggcacttctccggaag
gccagctccctgccccccaccacagcccatattctcagtgccctgctggaatcgagggtg
aatctgcctcagtatccccctacagctatggactacaagtgccatctcaaaaagcataat
gagcgtcagttctttctggaactggtcaaggatatctccaatgaccttgaccttaccagc
ctgagctacaagatcctcatctttgtctgcctcatggtggatgctgaccgctgctctctc
ttcctggtagaaggggcagctgctggcaagaagagtttggtctccaaatttttcgatgtg
catgcaggaaccccactgctgccctgcagcagcacagagaactcaaacgaggtacaggtc
ccttggggcaaaggcatcattggctatgtcggggaacatggagaaacagtcaacattcct
gatgcctaccaggatcgaagattcaatgatgaaattgacaagctaactggatacaagaca
aaatcactgttgtgcatgcccatccgaagcagtgatggtgagattattggtgtggcccaa
gcgataaataagattcctgagggtgctccatttaccgaagatgatgaaaaattcattgac
tacctaccgaggtatcggatatggctgttgattacctgcaaggttatgcagatgtatctt
ccgttttgtggaattgccatatctaatgctcagctatttgctgcctcaaggaaagaatat
gaaagaagcagggcgttgctagaggtggttaatgacctctttgaagaacagactgacctg
gagaaaattgtcaagaaaataatgcatcgggcccaaactctgctgaaatgtgagcgctgt
tctgttttactcctagaagacattgaatcgccagtggtgaagtttaccaaatcctttgaa
ttgctgtctccaaagtgcagtgccgacaccgagaacagtttcaaagagagcatggagaaa
tcatcgtactctgactggctaataaataacagcatcgccgagctggtggcttctacaggt
cttccagtgaacatcagtgatgcctaccaggaccctcgctttgatgctgaggctgaccag
atatctggttttcacataagatcagttctctgcgtacctatttggaatagcaaccaccaa
ataattggagtggctcaagtgttaaatagacttgacggaaaaccttttgatgatgcggac
caacggctttttgaggcttttgttatcttttgtggccttggcatcaacaacacaattatg
tacgatcaagtgaagaagtcttgggcgaagcagtccgtggctcttgatgtgctatcatac
catgcaacatgttcaaaagctgaagttgacaagtttaaggcagccaacatccctctggtg
tcagaacttgccatcgatgacatacattttgacgacttttctcttgacgttgatgctatg
atcacagctgctcttcggatgttcatggagctggggatggtacagaaatttaaaatcgac
tatgagacactgtgtaggtggcttttaaccgtgaggaaaaattatcgaatggttctgtac
cacaactggagacatgccttcaacgtgtgccaactgatgtttgcgatgttaactactgct
gggtttcaagagattctgaccgaggtggaaattttagcggtgattgtgggatgcttgtgt
catgacctcgaccacaggggaaccaacaatgccttccaagctaagagtggctctgccttg
gcccaactctatgggacctctgccaccttagagcaccaccactttaaccacgccgtgatg
atccttcaaagtgagggtcacaacatctttgctaatttgtcctccaaggaatacagtgac
ctcatgcaacttctgaagcagtcaatattggcaacagatctcactctgtactttgagagg
agaactgaattctttgaactcgtcagtaaaggagaatatgattggaacatcaaaaaccat
cgtgatatatttcgatcaatgttaatgacagcctgtgaccttggagccgtgaccaaaccg
tgggagatctcaagacaggtggctgaacttgtaaccagtgagttctttgaacaaggagat
cgggagagagcagaactcaaactcattccttcagctatttttgatcgaaaccggaaagat
gaactgcctcggttgcagctggagtggattgatagcatctgcatgcctttgtatcaggca
ctggtgaaggtcaatgcgaaactgaagccaatggtggattcggtggctgcgaacagaagt
aaatgggaagagctgcatcggaaaaggctgctagtctcagctgcctcaccctcctctgcc
agcctcctggtggcaggggcagacagtaactaa

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