Rousettus aegyptiacus (Egyptian rousette): 107515075
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Entry
107515075 CDS
T06036
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04217
Necroptosis
ray04380
Osteoclast differentiation
ray04620
Toll-like receptor signaling pathway
ray04621
NOD-like receptor signaling pathway
ray04630
JAK-STAT signaling pathway
ray04658
Th1 and Th2 cell differentiation
ray04659
Th17 cell differentiation
ray05145
Toxoplasmosis
ray05160
Hepatitis C
ray05161
Hepatitis B
ray05162
Measles
ray05164
Influenza A
ray05165
Human papillomavirus infection
ray05167
Kaposi sarcoma-associated herpesvirus infection
ray05168
Herpes simplex virus 1 infection
ray05169
Epstein-Barr virus infection
ray05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107515075 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
107515075 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
107515075 (TYK2)
04621 NOD-like receptor signaling pathway
107515075 (TYK2)
04658 Th1 and Th2 cell differentiation
107515075 (TYK2)
04659 Th17 cell differentiation
107515075 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
107515075 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
107515075 (TYK2)
05160 Hepatitis C
107515075 (TYK2)
05171 Coronavirus disease - COVID-19
107515075 (TYK2)
05164 Influenza A
107515075 (TYK2)
05162 Measles
107515075 (TYK2)
05168 Herpes simplex virus 1 infection
107515075 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
107515075 (TYK2)
05169 Epstein-Barr virus infection
107515075 (TYK2)
05165 Human papillomavirus infection
107515075 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107515075 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ray01001
]
107515075 (TYK2)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107515075 (TYK2)
Protein kinases [BR:
ray01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107515075 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
FERM_C_FAK1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
107515075
NCBI-ProteinID:
XP_016008932
LinkDB
All DBs
Position
Unknown
AA seq
1185 aa
AA seq
DB search
MPLCHWGSKPDGDGAQLMATRGGLKVLLHWAGPGGGEPWVTFNEATLTAEDVCMHIAHKV
GISPPCLGLFALFDAQAQVWLPPNYILEVSRDTSLTLHFRMRWTKAFGRFYFRNWHGTNP
QEPAVYRCSPPGAKASSEQAEQGMQLLDSASFEYLFEQGKHEFVNDVASLWDLSNEEEIH
HFKNESLGMAFLHLCHLAICLGVPLKKVARKISFKDCIPRSFRQQIQQHNAFTQLRLQII
FHKFLWAFQPGHLSQQVIMVKYLATLEQLAPRFGTEHVPVCHLELLAQAKGEPCYVKDSR
QAPPEPRPEPAPGPPTHEVLVTGTGGIQWRPVQAEGPSGGDGGRRRNPHAGSSGKKAKAQ
ELVTQPVDRPQEAPWTYFCDFQDITHVVLRECHVSIHCQDKCLKLTLPSQAMALSLVSLV
DGYFRLTADSNHYLCHEVAPPRLVMSIQDGVHGPLLEPFVLAKLRPEDGLYLIHWSTNHF
NRLILTVAQKDQAPGGQCLRLRKFPIELHAGTFTMESWDRSFPSVRELRAALQGYLLRAG
DDCFSLRHCCLPQPGEISNLIIRWGPQASTKPLNLSQLSFHRVCQDDITQLSHLGQGTRT
NVYEGLLRVSDRGPEEDKADGGDSPTAGRGHGQELRVVLKVLDSSHHGIALAFYETASLM
SQVSHMHLAFVHGVCVHGSKNIMVAEYVEHGPLDVWLRRERGCVPVAWKVVVAQQLASAL
SYLEDKSLVHGNVCGRNILLARPGLAEGTSPFIKLSDPGVGLGTLSREERVERIPWMPPE
CLSGGANSLSTGADKWGFGATLLEICFNGEAPLQDRSPSEKEHFYQKQYQLPEPSCLELA
MLTSQCLTYEPAQRPSFRTILRDLTRLQPQNLVDVLAVNPDCQASDPTVFHKRYLKKIRD
LGEGHFGKVSLYCYDPTNDSTGEMVAVKALKAGCSPQLSTGWRREIDILRTLSHKNIVKY
KGCCEDQGKKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHTQHYIHR
DLAARNVLLDNNRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYAS
DVWSFGVTMYELLTYCDSSQSPPSKFIELIGFTQGQMTVLRLTELLERGERLPRPEKCPC
EIYLLMKKCWKAEASFRPTFQNLIPILKTAHEKYQGQAPSVFSVC
NT seq
3558 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccactggggcagcaagcctgatggggatggagcccagctcatggccacc
agaggaggcctgaaggtactcctgcactgggctggccccggtggtggggagccctgggtc
accttcaacgaggccacactgactgcagaggacgtctgcatgcacattgcacacaaagtc
ggcatctctccaccttgcctcggtctctttgccctcttcgatgcccaggcccaggtctgg
ctgcccccaaactacattctagaggtctccagagatacaagcctgacgttgcacttccgc
atgaggtggacaaaagcctttggaagattttatttccggaactggcatggcacaaatcct
caggagccagccgtgtaccgctgcagtcccccaggggccaaggcttcgtcagaacaggca
gagcagggcatgcaactcctggactcagcctcctttgagtacctctttgagcagggcaag
catgagtttgtgaatgacgtagcatcgctgtgggacctgtcgaatgaggaagagatccac
cactttaagaatgagagcctgggcatggcctttctgcacctctgccaccttgctatctgc
cttggtgttcccctaaagaaggtggccagaaagatcagcttcaaggactgcatcccgcgt
tccttccggcaacagatccagcaacacaatgcgttcacacagctgcgcctgcagatcatc
ttccacaagttcctgtgggccttccagccaggccatctctcccaacaggtcatcatggtc
aagtacctggctacactcgagcagctggcgccccgctttggcacagagcacgtgcctgtg
tgccacctagagctgttggcccaggccaaaggggagccatgctacgtcaaggacagtagg
caggcccctccagagcccaggcccgagcctgctccaggaccccctacccatgaggtgctg
gtgactggcactggtggcatccagtggcggccagtacaggcagagggtcccagtggtggt
gatggtggcaggagaaggaatccccatgctggctcatctgggaagaaagccaaggcccaa
gagttggtcacccaacccgtggataggccgcaggaggcaccgtggacctacttctgtgac
ttccaggacatcacccacgtggtactgagagaatgccatgtcagcatccactgtcaggac
aagtgcctgaagctgactctgccttcccaggccatggctctgtccttggtatcactggtg
gatggctatttccgcctgacggccgactcaaaccactacctatgccatgaagtggctcct
ccacggctggtgatgagtatccaggatggtgtccacggacccctgctggagccattcgtg
ctggccaagctacggccagaggatggcctctatctcatccactggagcaccaaccacttc
aaccgcctcatcctcacggtggcccaaaaagaccaggcacctggtggacagtgcttgcgc
ctgcggaagttccccattgagctgcatgcagggaccttcacaatggagagctgggacagg
tccttccccagtgtgcgtgagcttcgggctgccctgcagggctacttgctgcgggctggg
gatgactgcttctctctgcgccactgctgcctgccgcagccaggagagatctccaacctc
attatcaggtgggggcctcaggccagcaccaaacctctcaacctcagccagctcagcttc
caccgggtctgccaggatgacatcacccagctgtcccacttaggccagggcacaaggacc
aatgtgtatgagggcctcttgagagtgagtgacagaggacctgaggaagacaaggcagat
ggtggcgactcccccacagcaggcaggggccatgggcaggagctgcgagtggtgctgaag
gtgctagactccagccaccatggcatcgccctggccttctacgagacagccagcctcatg
agccaggtatcccacatgcacttggccttcgtccatggcgtctgcgtgcatggctccaag
aacatcatggtggcagagtacgtggaacatggacccctagacgtgtggctgcggcgggag
aggggctgcgtgcctgtggcctggaaggtggtggtggcccaacaactggccagcgccctc
agttacctggaagacaagagcctggtgcatggtaatgtgtgtggccggaacatcctgctg
gcacgtccagggttggcggagggcaccagcccattcatcaagctgagtgaccccggcgtg
ggcctgggtaccctctccagggaggaacgggtagagcggatcccctggatgcccccggag
tgcctgtctggtggggccaacagcctaagcacaggagctgacaagtggggttttggcgcc
accctcctggagatctgcttcaatggggaggctcccctgcaagaccgcagcccctccgag
aaagagcatttctaccagaagcaataccagctgcctgaaccgtcgtgcctggagctggcc
atgcttaccagccagtgcctgacctatgagccagcccaacgaccttccttccgcaccatc
ctgcgtgacctcactcggctgcagccgcaaaatcttgttgacgtcttggctgtgaatcca
gactgtcaggcgtcagaccccactgttttccacaagcgctatttgaaaaagatccgggat
ctgggcgagggtcactttggcaaggtcagcctgtactgctacgatccgaccaatgacagc
actggcgagatggtggccgtgaaggcccttaaggcgggctgcagcccccagctcagcacc
ggctggaggcgggagatcgacatcctgcgcacgctctcccacaagaacatcgtcaaatac
aagggctgctgcgaagaccaaggcaagaaatcagtgcagctcgtcatggagtatgtaccc
ctgggcagcctccgagactacctgccccggcacagcgtcggcctggcccagctgctgctg
tttgctcagcagatctgtgagggtatggcctacctgcacacccagcactacatccaccga
gacctggctgcgcgcaacgtgctgctggacaacaataggctggtcaagattggcgacttc
ggcctagccaaagctgtgcctgaaggccacgagtactaccgcgtgcgcgaggatggggac
agccctgtgttctggtacgccccagagtgcctgaaggagtgtaagttctactatgcatct
gacgtctggtcctttggggtcaccatgtatgaactgctgacctactgtgactccagccaa
agccccccttcgaaatttatcgagctcataggcttcacccaggggcagatgacagtattg
aggctcacagagctgctggagcgaggagagaggctgccacggccagagaaatgtccctgt
gagatctatctcctcatgaagaagtgctggaaggcagaggcctcattccgtccaaccttc
cagaacctcatacccatcctgaaaacagcccacgagaaataccagggccaggccccctcc
gtgttcagtgtctgctga
DBGET
integrated database retrieval system
