Rousettus aegyptiacus (Egyptian rousette): 107515262
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Entry
107515262 CDS
T06036
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00270
Cysteine and methionine metabolism
ray00480
Glutathione metabolism
ray01100
Metabolic pathways
ray01240
Biosynthesis of cofactors
ray04216
Ferroptosis
Module
ray_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
107515262 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
107515262 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
107515262 (GCLC)
Enzymes [BR:
ray01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
107515262 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
107515262
NCBI-ProteinID:
XP_016009361
UniProt:
A0A7J8K8U7
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEKVLETLQEKGERSNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEEGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIELTIDKAIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGSAVVDGCGKSQNSAELAAEEYTLMSIDTIVNGKEGVFPGLIPVLNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELHGPAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggatcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggatgtgctcaagtggggcgacgaggtagaatatatgttggtgtcttttgatcat
gaaaataaaaaagtccagttggtcctgtctggagaaaaagttcttgaaactctacaagaa
aaaggggaaaggtcaaacccaaaccatcctaccctttggagaccagagtatgggagttac
atgattgaagggacaccaggacagccctacggaggaacaatgtctgagttcaacacagtc
gaagacaacatgagaaaacgccggaaagaggcaacttctttattaggagaaaatcaggct
ctttgcacgataacttcatttcccagattaggctgtcctgggttcacgctgcctgagttc
aaacccaacccagtcgaagaaggcgcttccaagtccctcttctttcccgatgaagcaata
aacaagcatccccgcttcagcaccctaacaagaaatatccgacataggagaggagaaaag
gttgtcatcaacgtaccaatttttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaggcagcaaaggcttctaagcctgatcatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtaacattccaagcttgcagcatatct
gaggctagatacctttatgatcagttggccactatctgcccaattgtgatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggaaagaggactggagccactgaagaacaat
aactacaggattagtaaatcccgatatgattcaatagacagttatttatctgagtgcggt
gagaaatataatgacatcgagttgacaatagataaagcaatctatgaacaactgttacag
gaaggcattgatcatctcctggcccagcatgttgctcacctctttattagagacccactg
actctgtttgaagagaaaatacacctggatgatgccaacgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagcctcctcctccaaactcagatatc
ggatggagagtagaattccgacccatggaggttcagttaacggactttgagaactctgca
tatgtggtgtttgtcgtgctgctcactagagtgatcctttcgtacaaactggattttctc
attccgctgtcaaaggttgatgaaaacatgaaagtagcacagaaacgagatgctgttctg
cagggaatgttctatttcaggaaagacatttgcaaaggtggcagcgccgtggtggacggc
tgcggcaagtcccagaacagcgcggagctggcggcggaggagtacaccctgatgagcatc
gacaccatcgttaacgggaaggaaggtgtgtttcccgggctaatcccagttctgaactcc
taccttgaaaacatggaggtagatgtggacaccagatgtagtattctgaactacttaaag
ctgattaagaagagagcatcgggagaactaatgacagttgcaaaatggatgagagagttt
attgcaaaccatcctgactacaagcaagacagtgtgataactgatgaaatgaactatagc
cttattttaaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttacatgga
ccagcatttaggaaagtgaaatacagtggaagtaaaaccgactcttccaactag
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