Rousettus aegyptiacus (Egyptian rousette): 107516546
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Entry
107516546 CDS
T06036
Symbol
LRP6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6 isoform X1
KO
K03068
low density lipoprotein receptor-related protein 5/6
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04150
mTOR signaling pathway
ray04310
Wnt signaling pathway
ray04928
Parathyroid hormone synthesis, secretion and action
ray05010
Alzheimer disease
ray05022
Pathways of neurodegeneration - multiple diseases
ray05200
Pathways in cancer
ray05224
Breast cancer
ray05225
Hepatocellular carcinoma
ray05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
107516546 (LRP6)
04150 mTOR signaling pathway
107516546 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
107516546 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107516546 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
107516546 (LRP6)
05226 Gastric cancer
107516546 (LRP6)
05224 Breast cancer
107516546 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
107516546 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
107516546 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ray04131
]
107516546 (LRP6)
Membrane trafficking [BR:
ray04131
]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
107516546 (LRP6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ldl_recept_b
FXa_inhibition
Ldl_recept_a
Vgb_lyase
DUF5050
SGL
EGF_LRP2
cEGF
EGF
Motif
Other DBs
NCBI-GeneID:
107516546
NCBI-ProteinID:
XP_016011853
UniProt:
A0A7J8JIS8
LinkDB
All DBs
Position
Unknown
AA seq
1613 aa
AA seq
DB search
MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVF
GHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIE
VSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFIIINTE
IYWPNGLTLDYQEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWT
DWNTHSILACNKHTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMS
PVKPFYQCACPTGVKLLENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIR
HAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWT
DTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSD
RVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTL
LGDYVYWTDWQRRSIERVHKRSAEREIIIDQLPDLMGLKATNVHRIIGSNPCAEENGGCS
HLCLYRPQGLRCACPIGFELISDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTG
VKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLY
WADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDG
SERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQ
YQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHC
SHLCLAVPVGGFVCGCPAHYSLNSDNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILP
IHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSSVPNQNLEIQPYDLS
IDIYSRYIYWTCEATNVINVTRLDGRSIGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERS
PKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLE
DSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQ
EYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGE
IDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEK
NCEVLCLIDQFRCANGQCIGKHKKCDHNVDCSDKSDEVDCYPTEEPTPQATNTVGSVIGV
IVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHGPASVPLGYVPHPGSLSGSLPGMS
RGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTM
EFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSVATAKGYTSDL
NYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS
NT seq
4842 nt
NT seq
+upstream
nt +downstream
nt
atgggggccgtcctgaggagcctcctggcctgcagtttctgcgtgctcctgagagcggcc
cctttgctgctttatgcaaacagacgggacttacgattggttgatgctacaaatggcaaa
gagaatgctacgattgtagttggaggcttggaggatgcagctgcagtggactttgtgttt
ggtcatggcttgatatactggagtgatgtcagcgaagaagccattaaacgaacagagttt
aacaaaactgagagtgtacagaatgttgttgtttccggattattgtcccccgatgggttg
gcatgcgattggcttggagaaaagttatattggacagattctgaaactaatcggattgaa
gtttctaatttagatggatctttacgaaaagttttattttggcaagagttggatcaaccg
agagctattgccttagatccttcaagtgggttcatgtactggacagactggggagaagta
ccaaagatagaacgtgctggaatggatggttcaagtcgtttcattataataaacactgaa
atttactggccaaatggattgactttggattaccaggaacagaagctttattgggcggat
gcaaaacttaatttcatccataaatcaaatctggatggaacaaatcggcaggcagtggtt
aaaggttcccttccacatccttttgccttgacgttatttgaggacacattgtactggact
gattggaatacacactccattttggcttgcaacaagcacactggcgagggtctgcgtgaa
atccattctaacatcttctctcccatggatatacatgctttcagccagcagaggcagcca
aatgctacaaatccatgtggaattgataatggtggttgttcccacttgtgtttgatgtct
ccagtcaagcctttttatcagtgtgcttgcccgactggggtcaaactcctggagaatgga
aaaacctgcaaagatggtgccactgaattgttgcttttagcccgaaggacagacttgaga
cgcatttctttggatacaccagacttcacagacattgttctacagttagaagacatccgt
catgccattgcgatagattatgaccctgtggaaggctatatctactggactgatgatgaa
gtgagggccatacgccgctcattcatagatggatctggcagtcagtttgtggtcaccgct
caaattgcacaccctgatggtattgctgttgactgggttgcccgaaatctttattggaca
gacactggcactgatcggatagaagtgacaaggctcaatggcaccatgaggaagatcttg
atttcagaggacttagaggaaccccgggctattgtgttagatcccatggttgggtacatg
tattggactgactggggagaaatcccgaaaattgagcgagcagctctggatggttctgac
cgagtagtgttggttaacacttctcttggttggccaaatggtttagccttggattatgat
gaaggcaaaatatactggggagatgccaaaacagacaaaattgaggttatgaataccgat
ggcactgggagacgagtcctagtggaagacaaaattcctcacatatttgggtttactttg
ttgggtgactatgtttactggactgactggcagaggcgtagcatcgaaagagtacacaaa
cgaagtgcagagagggaaatcatcatagatcagctccctgacctcatgggcttaaaggcc
acaaatgttcatagaatcatcggttccaacccctgtgctgaggaaaatgggggatgtagc
catctttgcctctatagacctcagggacttcgctgtgcctgtcccattggctttgaactc
atcagtgacatgaagacctgcattgtcccagaggcttttcttttgttttcacggagagca
gatatcaggagaatttctttggaaactaacaataataatgtagccattccgctcactggt
gtcaaagaagcttctgctttggattttgatgtgacagacaaccgaatttactggactgat
atatcactcaagaccatcagcagagcctttatgaatggcagtgcactggaacatgtggta
gagttcggcttagattatccagaaggcatggcagtggactggcttgggaagaacttgtac
tgggcagacacaggaacaaatagaattgaggtgtcaaagttggatgggcagcaccgacaa
gttttggtgtggaaagacctagatagtcccagagctcttgcgttggaccctgctgaagga
tttatgtattggaccgagtggggtggaaaacctaagatagacagagctgccatggatgga
agtgagcgtactacattagttccgaacgtgggacgtgcaaatggcctaactattgattat
gctaaaaggaggctctattggacagacctggacaccaacttaatagaatcttcaaatatg
cttggactcaaccgtgaagttatagcagatgacttgcctcatccttttggcttaactcag
taccaagattacatctattggacggactggagccgacgcagcattgaacgtgccaacaaa
actagtggccaaaaccgcaccatcattcaaggccatttggattatgtgatggacatcctc
gtctttcattcctctcggcaggcaggatggaatgagtgtgcttccagcaatgggcactgc
tcccacctctgcttggctgtgccagttggaggttttgtttgtggatgccctgcccactac
tctcttaattctgacaacaggacttgtagtgctccaactactttcctgctcttcagtcag
aagagtgccattaaccgcatggtgattgatgaacaacagagccccgatatcatccttccc
attcacagccttcgaaatgtccgggccattgactatgacccactggacaagcaactctat
tggattgactcacgacaaaacatgatccgaaaagcacaagaagatggtagccagggcttt
actgtggtggtaagctcagttcctaatcagaacctagaaatacaaccctatgacctcagc
attgatatttatagccgctatatctactggacttgtgaggctaccaatgtcatcaacgta
acaagattagatggaagatcaattggagtggtgctaaaaggggagcaagacagaccgcga
gccattgtggtaaatccagagaaagggtatatgtattttactaatcttcaggaaagatct
cccaaaattgaacgagctgctttggatggaacagaacgagaggtcctctttttcagtggc
ttaagtaaaccaattgctttagcccttgatagccgattgggcaaactcttttgggctgat
tcagatctccggcgaattgaaagcagtgatctctcaggtgccaaccggatagtattagaa
gactccaatatcttgcagcctgtgggactgactgtatttgaaaattggctatattggatt
gataagcagcagcaaatgattgaaaaaattgacatgacaggtcgagagggtagaactaaa
gtccaggctcgaattgcccagcttagtgatattcatgcagtaaaggagctgaaccttcag
gaatatagacaacatccatgtgctcaggataatggtggctgttcacacatttgtcttgta
aaaggagatggtactacaaggtgttcttgccccatgcacttggttctgcttcaagatgag
ctgtcatgtggagaacccccaacatgttctcctcagcagtttacctgtttcacgggagaa
attgactgtatccctgtagcttggcgttgcgatggatttactgaatgtgaagaccatagt
gatgagctcaattgtcctgtgtgctcagaatcccagttccagtgtgccagtgggcaatgt
attgatggtgccctccgatgcaatggagatgcaaactgccaggataaatcagatgagaag
aactgtgaagtgctttgtttaattgatcagtttcgctgtgccaatggtcagtgcattgga
aaacataagaaatgtgatcataatgtggattgcagtgacaaatcagatgaagtggattgt
tatccaactgaggagccaacaccacaggccaccaatacagttggttcagtcattggtgtc
attgtcaccattttcgtgtctggaaccatatactttatctgccagaggatgttgtgtcca
cgtatgaagggagatggggaaaccatgactaatgactatgtagttcatggaccagcttct
gtgccccttggttatgtgccacacccaggttctttatcaggatctcttccaggaatgtct
cgaggtaaatcaatgatcagctcccttagtatcatggggggaagcagcggacccccttat
gaccgagctcatgtcacaggagcatcatcaagtagttcttcaagcaccaaaggcacttac
ttccctgcaattttgaaccctccaccatccccagccacagagcgatcacattacactatg
gaatttggttattcttcaaatagtccttccactcataggtcctacagctacaggccatac
agttaccggcactttgcaccccccaccacaccctgcagtacagatgtttgtgacagtgac
tatgctcccagccggagaatgacctcagtggcaacagccaagggctacaccagtgacttg
aactatgactcagagcctgtgcccccacctcccacaccccgaagccaatacttgtcagca
gaagagaactatgaaagctgcccaccttctccatacacagagaggagttactctcatcac
ctctacccaccgccaccctctccctgtacagactcctcctga
DBGET
integrated database retrieval system
