Rousettus aegyptiacus (Egyptian rousette): 107519587
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Entry
107519587 CDS
T06036
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00230
Purine metabolism
ray00670
One carbon pool by folate
ray01100
Metabolic pathways
ray01523
Antifolate resistance
Module
ray_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
107519587 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
107519587 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
107519587 (GART)
Enzymes [BR:
ray01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
107519587 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
107519587 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
107519587 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
107519587
NCBI-ProteinID:
XP_016017898
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSNHVKQVLVAPGNAGTACSEKISNAVISISDHSALAQ
FCKDEEIEFVVVGPEAPLAAGIVGSLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKPEEACSFIMSANFPALVVKASGLAAGKGVVVAESKEEACKAVQEIMQDKAF
GAAGETVIIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLLLKIKNTILQRTVDGMQQEGVPYTGVLYAGIMLTKDGPRVLEFNCRFGDPECQV
ILPLLKTDLYEVIQSTLDGLLCTSLPVWLENHTAITVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFHSGTALKDGKVVTNGGRVLTVTAIRENVISALEEAKKGLAAIKFEGAIYRRD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVRIIKPLAKATSRPGCAVDLGGFAGLFDLK
AAGFKDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIAKACGKAGCALLGGETAEMPDMYTPGEYDLAGFAVGAMERHQKLP
HLERISEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDLTKQILKDIQQHQEEAWVIGRVAACPEGSPRVKVRH
LIEAMQINGSVLENGTLKSHFTPQPKKARVAILISGTGSNLQALIDSTREPSSCSHIVVV
ISNKAAVPGLDKAARAGIPTRVITHNLYKSRVEFDTAVDQVLEEFSTDIICLAGFMRILS
GPFVRKWNGKLLNIHPSLLPSFKGPNAHEQALAAGVKVTGCTVHFVAEEVDAGQIILQEA
VPVKRGDTVATLSERVKSAEHKIFPAALQLVASGTVWLGENGQLCWVQEK
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcaatggaggaagagaacatacactggcctggaaa
cttgcacagtctaatcatgttaaacaggtgttggttgccccaggaaatgcaggcactgcc
tgctctgaaaagatttcaaatgctgtcatctccatcagtgatcacagcgcccttgctcag
ttctgcaaagatgaggaaattgaattcgtagttgttggaccagaggcaccactggctgct
ggaattgttgggagcctgacatctgcaggagtgcgatgctttggccccacagcagaagcg
gctcagttagagtccagcaaaagatttgccaaggagtttatggaccggcatggaatccca
actgcacagtggagagctttcaccaaacccgaagaggcctgcagcttcatcatgagtgcc
aacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggggtggttgtt
gcagagagcaaagaagaggcctgcaaagctgtacaagagatcatgcaggataaagctttt
ggagcagctggagaaacagttatcatcgaagaacttcttgaaggagaagaagtgtcttgt
ctatgcttcactgatggaaggactgtggcccccatgcccccagcgcaggaccataagcga
ttactggaaggagatcacggccccaacaccgggggaatgggcgcctattgcccagcacct
caggtttctaaggatttgttgctaaaaattaaaaataccattcttcagaggacagtggat
ggcatgcaacaggagggtgtgccatacacaggtgttctctatgctggtataatgctgact
aaggatggcccaagagttttggagtttaattgccgttttggtgatccagagtgccaagtc
atcctcccacttcttaaaactgatctttatgaagtgattcagtctaccttagatggcctg
ctatgtacctctctgcctgtttggcttgaaaatcacactgccataactgtcgtcatggca
agtaaaggttatccaggagactacaccaagggtgtggagataacagggtttcctgaggct
caggctttgggactggaagtgttccactcaggtactgccctaaaagatggcaaagtggtg
actaatggtggtagagtccttacagtaacagccatccgggaaaatgtcatctcagccctt
gaagaagccaagaaaggactagctgctataaagtttgagggagccatttacagaagggac
attggctttcgtgccatagctttcctccagcagcccaggggcctgacttataaggaatct
ggggtagacattgcagctggaaatatgctggtcaggataattaaacctttagcaaaagcc
acctctagaccaggctgtgctgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttttggcctgtggaacagatggcgttggaacaaaactg
aaaattgcccagcagtgcaataaacatgataccattggtcaggatttggttgcaatgtgc
gtaaatgatattttggcacaaggagcagagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcaatacaactgaagcggttgttgccggaattgctaaagcctgtgga
aaagctggatgtgctctccttggcggcgaaacagcagaaatgcctgacatgtatactcca
ggagagtatgacctagccggttttgccgtcggtgccatggagcggcatcaaaaactccct
cacctggaaagaatcagcgaaggggatgttgtcattggaatagcttcatctggtcttcac
agcaatgggtttagcctcgtgaggaaaattgtagcaaaatcttcccttcagtactcctct
ccagcacccgatggctgcggtgaccagaccttaggagacttgcttctaactccaaccaga
atctacagtcattcactcttacctgtattacgttcaggacatgtcaaggcctttgcccat
attactggtggaggattgctagaaaacatccccagagtcctccctcagaaatttggggtg
gatttagatgcccagacctggaggattcccaggatcttctcgtggttacagcaggaagga
cagctctctgaagaggagatggccagaacatttaactgtggggttggggctgccctcgtg
gtatcaaaggacctgacaaaacagattctgaaggatattcagcagcaccaggaagaagcc
tgggtgattggcagggtggcagcatgccctgaaggttctcctcgtgtgaaagtcaggcac
ctaatcgaagccatgcagataaatggatcagtattggagaatggcaccctgaaaagtcat
ttcactccccaaccaaaaaaggcaagagtggctatcttaatatctggaacaggatccaac
ctccaagctctgatagacagcactcgggagccgagcagctgttcacacattgtcgttgtc
atctccaacaaagccgcggtgcctggcttagataaagcagcgagagccggaattcctacc
agagtaattacccataacttatataaaagtcgtgtagaatttgacactgcagttgaccaa
gtccttgaagaattctccacagacataatctgtctcgcaggattcatgagaattttatct
ggcccctttgtcagaaaatggaatgggaaactactcaacatccacccttccttgctccct
tcttttaagggtccaaatgcccatgagcaagccctggctgccggtgtcaaagtaacaggg
tgcacggtgcactttgtagctgaagaagtagacgctggacaaattattttgcaagaagct
gttcctgtgaagaggggtgacactgttgcaactctgtctgaaagagtgaaatcagcagaa
cataaaatatttcccgcagccctccagctggtggccagtgggactgtgtggcttggagaa
aatggccagctctgttgggtccaggagaagtga
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