Rousettus aegyptiacus (Egyptian rousette): 107520240
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Entry
107520240 CDS
T06036
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00790
Folate biosynthesis
ray01100
Metabolic pathways
ray01240
Biosynthesis of cofactors
ray01523
Antifolate resistance
ray04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
107520240 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
107520240 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
107520240 (FPGS)
Enzymes [BR:
ray01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
107520240 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
107520240
NCBI-ProteinID:
XP_016019234
LinkDB
All DBs
Position
Unknown
AA seq
580 aa
AA seq
DB search
MSRARSHLRAAVFLTAVSPRGATSWIAARRELSARPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQMQLEAMELYLARSGLQVEDLDRLNIIHITGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWHLYHRLEETKDSNSCVSMPTYFR
FLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIVRKPVACGVSSLGIDHTNLLGDTMEKI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRERAEQTSCPLYLCPPLEALEEGGPPLTLGLEG
DHQRSNAALALQLAHCWLQQKDRQGVGEVKASRPSLVWQLPLAPVFQPTPHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTSSSVQACVRWFRQALNRHKEPRSGTEVRVLLFNATGDR
DAAALLKLLQPCQFDYAVFCPNLIEVSSMDNADQQNFTVTLDQVLLRCLEHQQHWNRLDE
EQACPEPGGPVSLLLAPRPAHSHSTSSLVFSCISQALQWISQGRDPVFHPRSPPRSLFAH
PVAGSGANVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcccgtagccacctgcgcgccgccgtctttctgacagccgtttctccgcgc
ggtgcaacgtcttggatcgccgcgcggcgagagttgagcgcgaggcccgcgccgcaagag
ccgggcatggagtatcaggatgctgtacgcacactcaacacccttcagaccaacgccagc
tacctggagcaggtgaagcgccagcgaggtgacccccagatgcagctggaagccatggag
ctgtacttggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccat
atcactgggaccaaggggaagggctccacctgtgccttcactgaacgtatcctccgaaac
tatggcctgaagacaggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgcatcaatgggcagcccatcagccctgagctcttcaccaagcacttctggcacctgtac
caccggctggaggagaccaaggatagcaacagctgtgtctccatgcccacctacttccgc
ttcctcacgctcatggccttccacatcttcctccaagagaaggtggacctggcagtggtg
gaagtgggtatcggtggggcttatgattgcaccaacatcgtcaggaagcctgtggcgtgc
ggggtctcttcccttggcatcgaccacaccaatcttctgggggacacgatggagaagatc
gcatggcagaaagggggcatcttcaagcgtggtgtccctgccttcaccgtgctccagcct
gacggtcctctggcagtgctgcgggagcgcgccgagcagacctcatgtcccctctacctg
tgcccaccactggaggctctggaggaaggggggccgccgctaaccctgggtctggaggga
gaccaccagcggtccaatgctgccttggccttgcagctggctcactgctggctgcagcaa
aaggaccgtcaaggtgtcggggaggtgaaggcgtccaggccaagcctcgtgtggcagctg
cctctggcacccgtgttccagcccacaccccacatgcggcacgggcttcgggacaccgag
tggctcggccggactcaggtgctgcggcgcgggcccctcacctggtacctggacggcgcg
catacctccagcagcgtgcaggcctgcgtgcgctggttccggcaggcgctgaaccgccac
aaggagccccggagtgggactgaggtgcgtgtcttgctcttcaacgctaccggggaccgg
gatgccgcggccctgctgaagctgctgcagccctgccagttcgactatgctgttttctgc
cctaacctaatagaagtgtcgtccatggacaatgcagaccagcagaacttcacagtgacg
ctggaccaggtgctgctccgctgcctggaacaccagcagcactggaaccgcctggacgag
gagcaagcctgccccgagcctggcgggcccgtgtccttgctgctggcaccccgcccagcg
cacagccacagcaccagctccctcgtcttcagttgcatctcccaagccttgcagtggatc
agccaaggtcgggaccctgtctttcacccacgcagtcccccacggagcctcttcgcccac
cccgtggcaggcagtggggccaacgtactccgcgaggccgctgccatccacgtgctggtc
acaggaagcctgcacctagtgggcggtgtcctgaagctgctggagccctccctgtcccag
tag
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