Rousettus aegyptiacus (Egyptian rousette): 107520319
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Entry
107520319 CDS
T06036
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00220
Arginine biosynthesis
ray00330
Arginine and proline metabolism
ray01100
Metabolic pathways
ray04020
Calcium signaling pathway
ray04022
cGMP-PKG signaling pathway
ray04066
HIF-1 signaling pathway
ray04071
Sphingolipid signaling pathway
ray04151
PI3K-Akt signaling pathway
ray04370
VEGF signaling pathway
ray04371
Apelin signaling pathway
ray04611
Platelet activation
ray04915
Estrogen signaling pathway
ray04921
Oxytocin signaling pathway
ray04926
Relaxin signaling pathway
ray04931
Insulin resistance
ray04933
AGE-RAGE signaling pathway in diabetic complications
ray05415
Diabetic cardiomyopathy
ray05417
Lipid and atherosclerosis
ray05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
107520319 (NOS3)
00330 Arginine and proline metabolism
107520319 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
107520319 (NOS3)
04371 Apelin signaling pathway
107520319 (NOS3)
04066 HIF-1 signaling pathway
107520319 (NOS3)
04020 Calcium signaling pathway
107520319 (NOS3)
04071 Sphingolipid signaling pathway
107520319 (NOS3)
04022 cGMP-PKG signaling pathway
107520319 (NOS3)
04151 PI3K-Akt signaling pathway
107520319 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
107520319 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
107520319 (NOS3)
04921 Oxytocin signaling pathway
107520319 (NOS3)
04926 Relaxin signaling pathway
107520319 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107520319 (NOS3)
05418 Fluid shear stress and atherosclerosis
107520319 (NOS3)
05415 Diabetic cardiomyopathy
107520319 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
107520319 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
107520319 (NOS3)
Enzymes [BR:
ray01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
107520319 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
107520319
NCBI-ProteinID:
XP_016019454
LinkDB
All DBs
Position
Unknown
AA seq
1200 aa
AA seq
DB search
MGNMKSVGQDPGPPCGLGLGLGLGLCSKQGPASPVSEPSWTPAPAPLPEPGHSPPPTRSP
EGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSQGPPPPEQL
LSQARDFINQYYSAIKRSGSQAHEQRLEEVEAQVAATGTYQLQESELVFGAKQAWRNAPR
CVGRIQWGKLQVFDARDCSSAQEMFTYICSHIKYSTNKGNIRSAITVFPQRAPGRGDFRI
WNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELF
TLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYTSTEIG
SRNLCDPHRYNILEDVAVCMDLDTRTSSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAA
TSSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGS
TARGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFR
KAFDPRVLCMDEYDVVFLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRP
EQHRSYKIRFNSVSCSDPLVSSWRRKRKASSNTDSAGALGTLRFCVFGLGSRAYPHFCAF
ARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAAQDI
FSPKRSWKRQRYRLTAQDECLQLLPGLMYVHRRKIFQATVLSVENLQSSKSTRATILVRL
DTGGKEGLQYQPGDHIGICPPNRPGLVEALLSRVEDLPPPGDTLAVEQLEKGSPGGPPPG
WVRDPRLPPCTLRQALTFFLDITSPPSPRLLQLLSTLAEEPGEQQELETLSQDPRRYEEW
KWFRCPTLLEVLEQFPSVALPAALLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLAYR
TQDGLGPLHYGVCSTWLSQLKAGNPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRG
FWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSREPGS
RKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELDEAG
DVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWSFDPPGSDTPGP
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacatgaagagcgtgggccaagaccctgggccgccctgcggcctggggctgggg
ctgggcctcgggctgtgcagcaagcagggcccagcctccccggtgtctgagcccagctgg
acgccagcacctgcacccctgcctgagccaggccacagccccccgcccacccggtcccca
gaggggcccaagttcccgcgcgtgaagaactgggaggtggggagcatcacctacgacacc
ctgagtgcccaggcacagcaggacggaccctgcaccccaagacgctgcctgggctccctg
gtatttccacggaaactgcagggccggccgtcccagggccccccaccccccgagcagctg
ctgagccaggccagggacttcatcaaccagtactacagcgccatcaagcggagcggctcc
caggcccacgagcagcggcttgaggaggtggaagcccaggtggcggccacaggcacctac
cagcttcaggagagcgagctagtgttcggggccaagcaggcctggcgcaacgctccccgc
tgcgtgggccggatccagtgggggaagctgcaggtgtttgacgcccgtgattgcagctct
gcgcaggagatgttcacctacatctgcagccacatcaagtactccaccaacaagggcaac
atccgctcggcaatcacagtgttcccccaacgcgccccgggccgcggggacttccgcatc
tggaacagccagctggtgcgctacgcgggctaccggcagcaggacggctccgtgcgcggg
gacccggccaacgtggaaatcaccgagctctgcatccagcacggctggaccccgggaaac
ggccgcttcgacgtgctgcccctgctgctccaggccccggacgagcccccagaactcttc
actctgccccccgagctggtcctcgaggtgcccctggagcaccccacgctggagtggttc
gcggccctgggcctgcgctggtatgccctcccggccgtgtccaacatgctgctggagatc
gggggcctggagttccccgcggcgcccttcagcggctggtacacgagcaccgagatcggc
tcgcggaacctgtgcgacccgcaccgctacaacatcctggaggatgtggccgtctgcatg
gacctggacacccggacgtcctcgtccctgtggaaagacaaggcagctgtggaaatcaac
ttggccgtgctgcacagttaccagctggccaaagtgaccattgtggaccaccatgcggcc
acctcctccttcatgaagcacctggagaacgagcagaaggcgagggggggctgccctgcc
gactgggcctggatcgtgccccccatctcgggcagcctcacccctgtcttccatcaggag
atggtcaactatttcctgtcccctgcctttcgctaccagccggatccttggaaggggagc
acagccaggggtgccggcatcaccaggaaaaagacctttaaggaagtggccaatgcggtg
aagatctctgcctcactcatgggcaccgtgatggccaagcgtgtgaaggccacaatcctg
tatggctctgagaccggccgggcgcagagctacgcacagcagctggggaggctcttccga
aaggctttcgacccccgggtcctgtgcatggatgaatatgacgtggtgttcctcgagcac
gagacgctggtgttggtagtgaccagcacatttgggaatggggatcccccagaaaacgga
gagagtttcgcagcggccctgatggagatgtccggcccctacaacagctcccctcggccc
gagcagcacaggagttacaaaatccgcttcaacagcgtctcctgctcagaccccctcgtg
tcctcctggcggcggaagagaaaggcgtccagtaacacggacagcgccggggccctgggg
accctcaggttctgcgtgttcgggctgggctcccgggcgtacccccacttctgcgccttt
gctcgtgcggtggacacgcggctggaagagctgggtggggagcggctcctgcagctgggc
cagggcgacgagctgtgcggccaggaggaggccttccgcggctgggcccaggctgccttc
caggcctcctgtgagaccttctgcgtgggcgaggacgccaaggccgccgcccaggacata
ttcagccccaaacggagctggaagcgccagaggtaccggctgacggcccaggatgagtgc
ctccagctgctgccaggcctgatgtatgtgcacagacgaaagattttccaggccacggtc
ctctcagtggaaaacctgcagagcagcaagtccactcgggctaccatcctcgtgcgcctg
gacaccggaggcaaggaggggctccagtaccagccaggcgaccacataggcatctgcccg
cccaaccggcccggcctcgtggaggcgctgctgagccgcgtggaggacctgccgccacca
ggggacaccttggcagtggagcagctggagaagggcagccctggtggccctcccccgggc
tgggtgcgggacccccggctgcccccatgcaccctgcgccaggctctcaccttcttcctg
gacatcacttccccgcccagcccccgactccttcaactgctcagcaccctggctgaagag
cccggggaacagcaggagctggagaccctcagccaggacccccggcgctacgaggagtgg
aagtggttccgctgccccacgctgctggaggtgctggagcagtttccgtcggtggctctg
cctgccgcgctgctcctcacccagctgcccctgctccagccccggtactactcggtcagc
tcggcgcccagcgcccaccccggagagatccacctcacagtggccgtgctggcctacagg
acccaggatgggctgggccccctgcactacggcgtctgctccacgtggctgagccagctc
aaggccggaaacccggtaccctgcttcatcaggggggctccctccttccggctgccacca
gaccccagcttgccctgcatcctggtgggcccaggcactggcatcgcccccttccggggc
ttctggcaggagcggctacatgacattgagagcaaagggctgcagcccgcccctatgacc
ttggtgttcggctgccgatgctcccagctggaccacctctaccgcgacgaggtgcaggac
gcgcagcagcgcggagtgtttggccgcgtcctcaccgccttctcccgggaacccggcagc
cgtaagacctacgtacaggacatcctgcggacagagctggccgccgaggtgcaccgcgtg
ctgtgcctcgaacgaggccacatgtttgtctgcggcgatgtcaccatggcaaccagcgtc
ctgcagacagtgcagcgcatactggcgacagagggcgacatggagctggatgaggccgga
gacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttcgggctcacg
ctacgcacccaggaggtgacaagccgcattcgcacccagagcttttccttgcaggagcgg
catctgcggggcgcagtgccctggtcgttcgacccgcccggctcagacacccccggcccc
tga
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integrated database retrieval system
