Rousettus aegyptiacus (Egyptian rousette): 107520704
Help
Entry
107520704 CDS
T06036
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
107520704 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ray03032
]
107520704 (TOP2A)
03036 Chromosome and associated proteins [BR:
ray03036
]
107520704 (TOP2A)
Enzymes [BR:
ray01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
107520704 (TOP2A)
DNA replication proteins [BR:
ray03032
]
Eukaryotic type
DNA Topoisomerases
107520704 (TOP2A)
Chromosome and associated proteins [BR:
ray03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
107520704 (TOP2A)
Centrosome formation proteins
Centriole proteins
107520704 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
107520704
NCBI-ProteinID:
XP_016020267
UniProt:
A0A7J8GIY2
LinkDB
All DBs
Position
Unknown
AA seq
1532 aa
AA seq
DB search
MEVSPLQPVNENMQINKTKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDTGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKNFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDR
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPQDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERAGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTALDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTGPTFNYLLDMPLWYLTKEKKD
ELCKLRKEKEQELETLKKKSPSDLWKEDLAAFVEELETVEAKEKQDEQVGLPGKGGKGKG
KKTQMAEVLPSPSGKRVIPRVTIEMKAEAEKKIKRKIKNENSEGTPQENGMEPEGLKQRL
EKKLKKEPGTRTKKQTTLPFKSVKKGKKRNPWSDSESDASNNESDFDVPPREVEPRRAAT
KTKFTVDLDSDEDFSDFDQETQDEDFVPSDASPVKTRTSPKRTNKELKPQKSTTSVTDFD
DDDDAKDDVPLSPSSPAADFPAETEVVNPVSQKNVTMKKTAAKSQSSTSTTGAKKRAAPK
RTRKDPGVNSDAPQKPDPPKTKTRRKRKPSTSDDSDSNFEKMISKAVTNKKSKGENDDFH
LDLDSAVAPRVKSGRAKKPIKYLEESDEDDLF
NT seq
4599 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaaatgaaaatatgcaaatcaacaaaacaaagaaa
aatgaagatgctaagaaaagactgtctgttgaaagaatctatcaaaagaaaacacaattg
gaacacattttgcttcgtccagacacctacattggctctgtggaattagtgacccagcaa
atgtgggtttacgatgaagatactggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacgattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatatttagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacgtggatggataacatggggaga
gctggtgagatggaactcaagccctttaatggagaagattatacatgtattaccttccag
cctgatttgtctaagtttaaaatgcagagccttgacaaagatattgttgcactgatggtt
agaagagcatatgatattgctggatccactaaagatgttaaagtctttctcaatggaaat
aagttgccagtgaaaggattccgtagctatgtggatatgtatttgaaggataaagtagat
gaaactggcaatccattgaaaatcatccatgaacaagtaaaccacaggtgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaagtcaagaactttggatcaacatgccaactaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggctcaa
atccagttaaacaagaagtgttctgctgtgaaacataacagaattaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactccactgagtgtacacttatcctgacc
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagataga
tatggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcacaaacag
ataatggaaaatgccgaaattaataatatcatcaagattgtgggtcttcaatacaagaaa
aactatgaagatgaagattcattgaagactcttcgctatgggaagataatgattatgaca
gatcaggaccaagacggttcccacatcaaaggcttgctgattaattttatccatcataac
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagtctgcctgaatttgaagaatggaagagt
tctacaccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tccaaagaagctaaagaatactttgcagatatgaaaagacatcgtatccagttcaaatac
tctggtcctgaagacgatgctgcgatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaagacaacgaaagttacttggcctt
cctgaggattacttgtatgggcaaacaaccacatatctgacatacaacgacttcataaac
aaggaactaatcctgttctcaaattctgataacgagagatctatcccgtctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacgtgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
caagatgatcacacattaaagttcttatatgatgacaaccagcgtgtggagcccgagtgg
tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg
tcctgcaaaattcccaactttgatattcgtgaagtcgtgaataatatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa
gaactggctccaaatcaatatgtgattagtggcgaagtggctattcttaattccacaacc
atcgaaatctcagagcttcccatcagaacatggacccagacatataaagaacaggttctg
gaacccatgttgaatggcacggagaagacacctcctctcataacagattatagggaatac
catacagataccactgtgaagttcgttgtgaaaatgactgaagaaaaactggcagaggcc
gagagagcgggactacacaaagtcttcaaacttcaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatatgacacagcgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggcgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataaacctaagaaagaattgattaaagttttgattcagagg
ggatatgattcggatcctgtgaaagcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaacgaagagagcgataatgaaaaggaaactgaaaagagtgactctgtaactgga
ccaaccttcaactacctccttgatatgcctctttggtatcttaccaaggaaaagaaagat
gaactgtgcaaattaagaaaggaaaaagaacaagagctagaaacattaaagaaaaagagt
ccatcagatttgtggaaagaagacttggctgcttttgttgaagagctggagactgttgaa
gccaaggaaaaacaagatgaacaagtaggacttcctgggaaaggagggaaaggaaaaggg
aaaaaaacacaaatggctgaagttttgccttcaccaagtggaaaaagagtcatcccccga
gttaccatagagatgaaagcagaagcagaaaagaaaattaaaaggaaaattaagaatgaa
aattctgaaggaacccctcaagagaatggtatggaaccagaaggcctaaaacaaagatta
gagaagaaactgaaaaaagaaccaggtaccaggacgaagaaacaaactacattgccattt
aaatcagtcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagatgcgagt
aataacgaaagtgattttgatgtccctccacgagaagtagagccacggagagcagcaaca
aaaaccaaattcacagtggatttagattcagatgaagatttctcagattttgatcaagaa
actcaagatgaagattttgtgccatctgatgctagtccagttaagacccgaacttccccg
aaacgtactaacaaagaactgaagccacaaaagagcaccacgtcagtaacagactttgat
gatgatgatgatgccaaggacgatgttccactttctccaagctctcctgctgctgatttc
ccagccgaaacggaagttgtaaaccctgtttctcaaaagaatgtgacaatgaagaaaaca
gcagcaaaaagtcagtcttccacctcgacgacgggtgccaaaaaaagggctgcaccaaaa
agaaccagaaaggatccaggcgtgaattctgatgcccctcaaaagcctgatcccccaaaa
accaagactcgccgcaaaaggaagccatccacttctgatgattccgactctaattttgag
aaaatgatttctaaagcagtcacaaacaagaaatccaagggggagaatgatgacttccat
ctggacttagactcagctgtggctcctcgtgtaaaatctgggcgagcaaagaagccgata
aagtacctcgaggaatcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
