Rousettus aegyptiacus (Egyptian rousette): 107521319
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Entry
107521319 CDS
T06036
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00562
Inositol phosphate metabolism
ray01100
Metabolic pathways
ray01521
EGFR tyrosine kinase inhibitor resistance
ray04012
ErbB signaling pathway
ray04014
Ras signaling pathway
ray04020
Calcium signaling pathway
ray04062
Chemokine signaling pathway
ray04064
NF-kappa B signaling pathway
ray04066
HIF-1 signaling pathway
ray04070
Phosphatidylinositol signaling system
ray04072
Phospholipase D signaling pathway
ray04360
Axon guidance
ray04370
VEGF signaling pathway
ray04380
Osteoclast differentiation
ray04611
Platelet activation
ray04613
Neutrophil extracellular trap formation
ray04625
C-type lectin receptor signaling pathway
ray04650
Natural killer cell mediated cytotoxicity
ray04662
B cell receptor signaling pathway
ray04664
Fc epsilon RI signaling pathway
ray04666
Fc gamma R-mediated phagocytosis
ray04670
Leukocyte transendothelial migration
ray04722
Neurotrophin signaling pathway
ray04750
Inflammatory mediator regulation of TRP channels
ray04919
Thyroid hormone signaling pathway
ray04933
AGE-RAGE signaling pathway in diabetic complications
ray04935
Growth hormone synthesis, secretion and action
ray05167
Kaposi sarcoma-associated herpesvirus infection
ray05169
Epstein-Barr virus infection
ray05170
Human immunodeficiency virus 1 infection
ray05171
Coronavirus disease - COVID-19
ray05200
Pathways in cancer
ray05205
Proteoglycans in cancer
ray05206
MicroRNAs in cancer
ray05214
Glioma
ray05223
Non-small cell lung cancer
ray05225
Hepatocellular carcinoma
Module
ray_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
107521319 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
107521319 (PLCG2)
04014 Ras signaling pathway
107521319 (PLCG2)
04370 VEGF signaling pathway
107521319 (PLCG2)
04064 NF-kappa B signaling pathway
107521319 (PLCG2)
04066 HIF-1 signaling pathway
107521319 (PLCG2)
04020 Calcium signaling pathway
107521319 (PLCG2)
04070 Phosphatidylinositol signaling system
107521319 (PLCG2)
04072 Phospholipase D signaling pathway
107521319 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
107521319 (PLCG2)
04613 Neutrophil extracellular trap formation
107521319 (PLCG2)
04625 C-type lectin receptor signaling pathway
107521319 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
107521319 (PLCG2)
04662 B cell receptor signaling pathway
107521319 (PLCG2)
04664 Fc epsilon RI signaling pathway
107521319 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
107521319 (PLCG2)
04670 Leukocyte transendothelial migration
107521319 (PLCG2)
04062 Chemokine signaling pathway
107521319 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
107521319 (PLCG2)
04919 Thyroid hormone signaling pathway
107521319 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
107521319 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
107521319 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
107521319 (PLCG2)
04380 Osteoclast differentiation
107521319 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107521319 (PLCG2)
05206 MicroRNAs in cancer
107521319 (PLCG2)
05205 Proteoglycans in cancer
107521319 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
107521319 (PLCG2)
05214 Glioma
107521319 (PLCG2)
05223 Non-small cell lung cancer
107521319 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
107521319 (PLCG2)
05171 Coronavirus disease - COVID-19
107521319 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
107521319 (PLCG2)
05169 Epstein-Barr virus infection
107521319 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
107521319 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107521319 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ray04131
]
107521319 (PLCG2)
Enzymes [BR:
ray01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
107521319 (PLCG2)
Membrane trafficking [BR:
ray04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
107521319 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
107521319 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
PH
SH3_9
EF-hand_PLCG1
PH_12
SH2_1
SH3_2
PH_14
Adhesin_E
GDPD
Motif
Other DBs
NCBI-GeneID:
107521319
NCBI-ProteinID:
XP_016021370
UniProt:
A0A7J8CKC7
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKVVRQKEDCCFTILYGSQFVLSTLSLAADSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKAILPMVNFKVGSA
KFLKDKFVEIGAHKDELSFEQFHLLYKKLMFEQQKSIFDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNKVRERMTRFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDIQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRYMARV
FKEVFGDLLLIKPTEASADQLPSPTQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEELPQDTPPTELHFGEKWFHKKVEKR
ISAEKLLQEYCSETGGKDGTFLVRESERFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYY
LTDNLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGTDSYAITFRAKGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTVDVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDKVEELFEWF
HSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVVRQKPIDLLKYNLKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatggtcaacgtggacacccttccggaatatgagaagagccagatcaagaga
gccctggagctgggcacggtgatgaccgtgttcagcttccgcaagtccaccccggagcgg
aggaccgtccaggtgatcatggagacgcggcaagtggcctggagtaagacggctgacaaa
atcgagggcttcttggatatcatggaaataaaggaaatccgccccgggaagaactccaag
gattttgagcgtgcaaaagtagtccgccagaaggaagactgctgttttaccatcttgtac
ggcagccagttcgtcctcagcacactcagtttagcagctgactctaaggaagatgcaact
aagtggctctctggcttgaagatcttacaccaagaagcaatgagtgcgtccacacccacc
attatcgagagttggctgagaaagcagatttattctgtggatcaaaccaggagaaatagc
atcagcctccgagagttgaaggccatcttgcccatggtcaatttcaaagtagggagtgcc
aagttcctcaaagataagtttgtggaaataggtgcacacaaagatgaactcagctttgaa
cagttccatctcctctataaaaagcttatgtttgaacaacaaaaatcgatttttgatgaa
ttcaaaaaagattcctccgtgttcatcttgggcaacaccgaccggccggatgcctccgct
gtccacctgcacgacttccagcggtttctcttacatgaacagcaggagctctgggctcag
gatctgaacaaagtccgtgagcggatgaccaggttcatcgatgacacgatgagggaaact
gccgagcccttcttgtttgtcgatgagttcctcacatacctgttttcacgggagaacagc
atttgggatgaaaagtatgacgtggtagacatacaggacatgaacaaccccttatcccat
tactggatctcctcatcacataacacgtaccttacaggtgaccagctgcggagcgagtca
tccacggaagcatacattcgctgtctgcgcatgggctgtcgctgcattgagctggactgc
tgggacgggcccgatgggaagcccatcatctaccatggctggacacggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaagaccatgcctttgtcacctcaagcttccct
gtgatcctgtccatcgaggagcactgttgcgtggagcagcagcgctacatggccagagtg
ttcaaggaggtgtttggcgacttgctgctgataaagcccacggaggccagtgccgaccag
ctgccctcgcccacgcagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggtgatgtagatgtcaacatggaggacaagaaagatgagcacaagcaacagggtgaa
ctgtacatgtgggattccattgaccagaaatggactaggcactactgcgccattgctgat
gccaagctatccttcagcgacgacatcgaacagactatggaagaggagctaccccaggat
acaccccccacagaactgcattttggagagaagtggttccataagaaggtggagaagagg
ataagtgccgagaagctactgcaggaatactgcagcgagacggggggcaaggatgggacc
ttcttggtgcgagagagtgagaggttccccaacgactacaccttgtccttctggcggtct
ggccgggtccagcactgccggatccgctccaccatggagggcggagtcatgaagtactac
ctgactgacaacctcatgttcaccagcatctacgccctcatccagcactaccgtgagacg
cacctacggtgtgccgagttcgagctccggctcaccgaccccgtgcccaaccccaacccc
catgagtcaaagccgtggtactatgatgggctgagccgtggagaagcagaggacatgctg
atgagggttccccgggacggagccttcctcatccggaagcgagaaggtaccgactcctac
gccatcaccttcagggccaagggcaaggtgaagcactgtcgcatcaaccgggatggccgg
cactttgtgctggggacctccgcctactttgagagcctggtggaacttgtcagttactac
gagaagcacgcgctctaccgaaagatgaaactgcgctaccctgtgacccccgagctcctt
gaacgctacaatatggaaagagatataaactccctgtatgatgtcagcagaatgtatgtg
gatcccagtgaaatcaatccttctatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcagagtgatgagctgagcttttgccgtggtgctctcattcacaacgtctcc
aaggaacccgggggctggtggaaaggagactacggaaccagaatccagcagtacttcccg
tctaattacgtcgaggacatttcaacagtggatgtggaggagctggagaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatattggatctcaacacctataacgtt
gtgaaagccccacaagggaaaaaccagaagcctttcgtctttatcctggagcccaagaag
cagggtgaccctccggtggagtttgccacggacaaggtggaagagctctttgagtggttt
cacagcattcgggagatcacctggaagattgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtcgattgccatcgagctctcggacctggtcgtctactgcaaaccaacc
agcaagaccaaggacaatttagaaaaccccgacttccgagaaatccgttcctttgtggag
acgaaggctgacagcgtcgtccgacagaaacccattgatctcctgaagtacaatctaaag
ggcctgacccgcgtttacccgaaggggcagagggtggactcctccaactatgatcccttc
cgcctctggctgtgtggctcccaaatggtggcgctcaatttccagacagcagataaatac
atgcagatgaatcaggccttgttttcactcaatgggcggactggctacgtcctacagcct
gagagcatgaggacggagaagtatgaccccatgccgcctgagtcccagcggaagatcctg
atgaccttgacggtcaaggttctcggggctcgacatcttcccaagcttggacgaagtatt
gcgtgtccctttgtggaggtggaaatatgtggagctgaatatgacaacaacaagtttaag
acgacggttgtgaatgacaatggcctaagccctgtttgggctccaacacaggagaaggtg
acatttgaaatttatgacccaaaccttgcatttctgcgctttgtggtgtacgaggaagat
atgttcagtgatcccaacttcctggctcatgctacctaccccattaaaggaatcaaatca
ggatttagatctgttcctctgaagaacgggtacagcgaagacattgaactggcttccctc
ctggttttctgtgagatgcggccagtcctggagagtgaagaggaactgtactcctcctgt
cgccagctgcggaggcggcaagaagagctgaacaaccagctctttctatatgacacacac
cagaacttgcgcaacgccaaccgggatgccctggtgaaagagttcaacgtcaacgagaac
cagctccagctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaac
agcaagttttactcatag
DBGET
integrated database retrieval system
