Rousettus aegyptiacus (Egyptian rousette): 107521461
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Entry
107521461 CDS
T06036
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X2
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00010
Glycolysis / Gluconeogenesis
ray00620
Pyruvate metabolism
ray01100
Metabolic pathways
ray01200
Carbon metabolism
ray01230
Biosynthesis of amino acids
ray04910
Insulin signaling pathway
ray04930
Type II diabetes mellitus
ray04932
Non-alcoholic fatty liver disease
ray04950
Maturity onset diabetes of the young
Module
ray_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ray_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
107521461 (PKLR)
00620 Pyruvate metabolism
107521461 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
107521461 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
107521461 (PKLR)
04950 Maturity onset diabetes of the young
107521461 (PKLR)
04932 Non-alcoholic fatty liver disease
107521461 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ray04147
]
107521461 (PKLR)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
107521461 (PKLR)
Exosome [BR:
ray04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
107521461 (PKLR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK
PK_C
HpcH_HpaI
IMPDH
Motif
Other DBs
NCBI-GeneID:
107521461
NCBI-ProteinID:
XP_016021643
UniProt:
A0A7J8BFF2
LinkDB
All DBs
Position
Unknown
AA seq
573 aa
AA seq
DB search
MSTQEDEKTQAPQLSSWLSRDLAKSFLIGAPGGPAGYLRRASVAQVTQELGAAAFQQQQL
PAAMADTFLEHLCLLDIDSEPVATCSTSIIATIGPASRSVELLKEMIKAGMNIARLNFSH
GSHEYHAESIANIREAVESFAASPLGYRPVAIALDTKGPEIRTGVLLGGPEAEVELVKGS
QVLVTVDPAFRTRGDAGTVWVDYPNIVRVVPVGGHIYIDDGLISLAVKKIGPKGLETEVK
NGGMLGSRKGVNLPGAQVDLPGLSEQDARDLRFGVEHGVDIVFASFVRKASDVVAVRAAL
GPEGQAIKIISKIENHEGVKKFDEILDVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCN
LAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVMMQ
HAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIVVLTTTGRSA
QLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGK
LRGFLHVGDLVIVVTGWRPGSGYTNIMRVLSIS
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atgtcgacccaggaggacgagaagacacaagccccgcagctttcctcatggctctctagg
gacttggcaaagtccttcctgatcggggctccgggagggccagcgggctacctgcggcgg
gccagcgtggcccaggtgacccaggagctgggcgccgccgccttccagcagcagcagctg
ccggccgcgatggcggacaccttcctggagcacctctgcctgctggacatcgactcggag
cccgtggccacgtgcagcaccagcatcatcgccaccatcgggccagcgtcgcgctctgtg
gagctcctcaaggagatgattaaggccgggatgaacattgcgcgactcaacttctcgcac
ggctcgcacgagtaccacgccgagtccatcgccaacatccgggaggcagtggagagcttt
gcagcttccccgctcggctaccgacccgtggccatcgctctggacaccaaaggaccggag
atccgcaccggcgtcttgctggggggccccgaggcggaagtggagctggtgaagggctcc
caggtgctggtgaccgtggacccggcgttccggacacggggggacgcgggcaccgtgtgg
gtggactaccccaacatcgtccgggtcgtgccggtgggcggccacatctacatcgacgac
gggctcatctccctggcggtcaagaaaatcggcccaaaggggctggaaacggaggtgaag
aatggcggcatgctgggcagccggaagggcgtgaacttgcctggcgcccaggtggacctg
cccgggctgtccgagcaagacgcccgggacctgcgcttcggggtagagcatggcgtggac
atcgtctttgcctcctttgtgcggaaagccagcgatgtggtcgcagtccgggctgcgctg
gggccggaaggacaagccatcaagatcattagcaaaatcgagaaccacgaaggcgtgaag
aagttcgatgaaatcctggatgtgagcgacggcatcatggtggcccggggtgacctgggc
attgagatcccagccgagaaggtcttcctggctcagaagatgatgatcgggcgttgcaac
ttggcgggcaagccggttgtctgcgccacccagatgctggagagcatgatcactaagccc
cggccgacgcgggcagagaccagcgacgtggccaacgccgtgctggacggggccgactgc
atcatgttgtcgggcgagaccgccaagggcagcttcccggtggaggccgtgatgatgcag
cacgcgatcgcgcgggaggcggaggccgcagtgtaccaccgacagctgtttgaggagctg
cgccgcgctgcgcccctgagccgcgaccccactgaggtcaccgccatcggcgccgtcgag
gctgccttcaagtgctgtgctgcggccatcgtcgtgctgaccaccactggccgctctgcc
cagctcctatctcggtaccgacctcgagcagctgtcattgctgttacccgctccgcccag
gccgcccgccaggcccacctgtgccgaggggtcttccccttgctgtaccgtgaacctcca
gaggccatctgggcggacgatgtggaccgccgggtccagtttggcatcgaaagtggaaag
ctccgtggcttcctccatgtcggggacctggtgatcgtggtgacaggctggcgacctggt
tctggctataccaacatcatgcgggtgctgagcatatcctga
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