Rhinopithecus bieti (black snub-nosed monkey): 108513636
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Entry
108513636 CDS
T04641
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521
EGFR tyrosine kinase inhibitor resistance
rbb01522
Endocrine resistance
rbb04010
MAPK signaling pathway
rbb04012
ErbB signaling pathway
rbb04014
Ras signaling pathway
rbb04062
Chemokine signaling pathway
rbb04068
FoxO signaling pathway
rbb04072
Phospholipase D signaling pathway
rbb04150
mTOR signaling pathway
rbb04151
PI3K-Akt signaling pathway
rbb04510
Focal adhesion
rbb04540
Gap junction
rbb04630
JAK-STAT signaling pathway
rbb04650
Natural killer cell mediated cytotoxicity
rbb04660
T cell receptor signaling pathway
rbb04662
B cell receptor signaling pathway
rbb04664
Fc epsilon RI signaling pathway
rbb04714
Thermogenesis
rbb04722
Neurotrophin signaling pathway
rbb04810
Regulation of actin cytoskeleton
rbb04910
Insulin signaling pathway
rbb04912
GnRH signaling pathway
rbb04915
Estrogen signaling pathway
rbb04917
Prolactin signaling pathway
rbb04926
Relaxin signaling pathway
rbb04935
Growth hormone synthesis, secretion and action
rbb05034
Alcoholism
rbb05160
Hepatitis C
rbb05161
Hepatitis B
rbb05163
Human cytomegalovirus infection
rbb05165
Human papillomavirus infection
rbb05200
Pathways in cancer
rbb05205
Proteoglycans in cancer
rbb05206
MicroRNAs in cancer
rbb05207
Chemical carcinogenesis - receptor activation
rbb05208
Chemical carcinogenesis - reactive oxygen species
rbb05210
Colorectal cancer
rbb05211
Renal cell carcinoma
rbb05213
Endometrial cancer
rbb05214
Glioma
rbb05215
Prostate cancer
rbb05220
Chronic myeloid leukemia
rbb05221
Acute myeloid leukemia
rbb05223
Non-small cell lung cancer
rbb05224
Breast cancer
rbb05225
Hepatocellular carcinoma
rbb05226
Gastric cancer
rbb05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
108513636 (SOS2)
04630 JAK-STAT signaling pathway
108513636 (SOS2)
04068 FoxO signaling pathway
108513636 (SOS2)
04072 Phospholipase D signaling pathway
108513636 (SOS2)
04151 PI3K-Akt signaling pathway
108513636 (SOS2)
04150 mTOR signaling pathway
108513636 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
108513636 (SOS2)
04660 T cell receptor signaling pathway
108513636 (SOS2)
04662 B cell receptor signaling pathway
108513636 (SOS2)
04664 Fc epsilon RI signaling pathway
108513636 (SOS2)
04062 Chemokine signaling pathway
108513636 (SOS2)
09152 Endocrine system
04915 Estrogen signaling pathway
108513636 (SOS2)
04917 Prolactin signaling pathway
108513636 (SOS2)
04926 Relaxin signaling pathway
108513636 (SOS2)
04935 Growth hormone synthesis, secretion and action
108513636 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
108513636 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
108513636 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108513636 (SOS2)
05206 MicroRNAs in cancer
108513636 (SOS2)
05205 Proteoglycans in cancer
108513636 (SOS2)
05207 Chemical carcinogenesis - receptor activation
108513636 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
108513636 (SOS2)
05231 Choline metabolism in cancer
108513636 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
108513636 (SOS2)
05225 Hepatocellular carcinoma
108513636 (SOS2)
05226 Gastric cancer
108513636 (SOS2)
05214 Glioma
108513636 (SOS2)
05221 Acute myeloid leukemia
108513636 (SOS2)
05220 Chronic myeloid leukemia
108513636 (SOS2)
05211 Renal cell carcinoma
108513636 (SOS2)
05215 Prostate cancer
108513636 (SOS2)
05213 Endometrial cancer
108513636 (SOS2)
05224 Breast cancer
108513636 (SOS2)
05223 Non-small cell lung cancer
108513636 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
108513636 (SOS2)
05160 Hepatitis C
108513636 (SOS2)
05163 Human cytomegalovirus infection
108513636 (SOS2)
05165 Human papillomavirus infection
108513636 (SOS2)
09165 Substance dependence
05034 Alcoholism
108513636 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108513636 (SOS2)
01522 Endocrine resistance
108513636 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
IQ_SEC7_PH
Motif
Other DBs
NCBI-GeneID:
108513636
NCBI-ProteinID:
XP_017704940
UniProt:
A0A2K6MLE2
LinkDB
All DBs
Position
Unknown
AA seq
1235 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFNEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCPFYSHQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSVVFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPTPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADKLA
IEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPAIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFERFFENLNPMGN
ASEKEFTDYLFNKSLEIEPRNCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPT
PLEREPCKISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSI
FAPVLLPHSKSFFSSCGSLHKLSEEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPP
RQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPP
PLGHLHRDSDWLRDISTCPNSPSTPPSTPSPRVPRRCYVLSSSQNNLAHPPAPPVPPRQN
SSPHLPKLPPKTYKRELSHPPLYRLPLLENAETPQ
NT seq
3708 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccttacgagttcttcagtgaggagaacagtccgaaatggcgg
ggactgttggtctcggccctgcggaaggttcaggaacaagtgcatcccactctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggcccagccaaggactgttcaagatgtagaggagcgagttcagaagacctttcctcac
ccaattgataaatgggccattgctgatgcacaatctgctatagaaaaacgaaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccttcgttgaaggaagtgttagggtac
aaagtggactaccatgtgtccctatatattgtggctgtactagaatatatctcagctgat
attttaaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcggataaggttttgatggacatgtttgatcaggatgat
ataggtttggtttctctctgtgaagatgaacctagttcttccggtgaattaaactactat
gatcttgtcagaactgaaatcgcagaagaaagacagtatctacgggaattaaatatgatc
ataaaagtgtttcgagaagcctttctttctgatagaaagctgtttaaaccttctgatatt
gaaaagatttttagtaacatttcagatatacatgaattgactgtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcgtttgatccttatgaaacattatcacaggacatt
ctttcaccagagtttaatgaacatttcaataaattgatggccagacctgcagttgctcta
cactttcagtccattgctgatggctttaaagaggcagttcgttatgtccttccacgtctt
atgctggtgccagtatatcactgttggcactattttgagttactaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccaaggtagcatggaccgaatttacaagcagcattcacctagacgccgacctggagat
cctgtttgccctttttatagtcaccaattaagaagcaaacacctggctatcaaaaaaatg
aatgaaattcagaaaaatatcgatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggagggaccattgacaagaatcggtgccaaacatgaacggcatattttt
ctgtttgatggcttaatgatcagttgtaaacctaatcatggccagactcggcttccaggt
tacagtagtgcagaatataggttaaaagaaaaatttgtcatgaggaaaatacaaatttgt
gataaagaagatacttgtgagtgcaagcatgcttttgaattagtatccaaagatgagaac
agcgtagtatttgctgctaagtctgctgaagaaaaaaacaactggatggcagccctgatt
tctcttcattatcgtagtactctagatcgaatgttagattcagtattactgaaagaagaa
aatgagcaaccactgagattaccaactcctgaagtatatcgttttgtagtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggcatccccattattaaa
ggaggaactgtagtgaagttaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttaccacatatcgttcattttgtaaaccacaggaattgctgagc
ttactgattgaacggtttgaaatcccagagccagaacctactgacgcagacaaattggca
atagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtatttcggcattgggttgaacatcatttttat
gactttgaaagagatttggaattgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaatcgctaagatcatcaagaggaagaagcaa
gctcaggcaaacggaataagccataatattacctttgaaagtccacctccagcaattgaa
tggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggagtctgatctctacaggaaagttcaaccatct
gaacttgtaggaagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctctggtttgaaaaatgcattgtggaagca
gaaaattttgaagaacgggttgcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggcgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagaccatacctttgagagattctttgaaaaccttaaccccatgggaaat
gcgtctgaaaaagagtttacagattatttgttcaacaagtcactagaaattgaacctcga
aactgcaaacagccacctcgatttcctagaaaatcaactttctccttgaaatctcctgga
ataaggcctaacacaggccgacatggctctacctcaggtactttacgaggtcacccaaca
ccattagaaagagaaccatgtaaaataagctttagtcggattgctgaaactgagctggaa
tcaacagtgtcagcaccaacttctccaaatacaccatctactccaccagtatctgcttct
tcagaccttagtgtatttttagatgtggatctcaacagctcctgtggcagcaatagcatc
tttgctccagtgcttttgccacattcaaagtctttctttagttcatgtggtagtttacat
aaactaagtgaagagcccctgattcctcctcctcttcctcctcgaaaaaagtttgatcat
gatgcttcaaattccaagggaaatatgaaatctgatgatgatcctcctgctattccaccg
agacagcctcctcctcccaaggtaaaacccagagttcctgttcctactggtgcatttgat
gggcctctgcatagtccacctccaccaccaccaagagatcctcttcctgatacccctcca
ccggttccccttcggcctccagaacactttataaactgtccatttaatcttcagccacct
ccactggggcatcttcacagagattcagactggctcagagacattagtacgtgtccaaat
tcgccaagcactcctcctagcacaccctctccaagggtaccacgtcgatgctatgtgctc
agttctagtcagaataatcttgctcatcctccagctccccctgttccaccaaggcagaat
tcaagccctcatctgccaaaactgccaccaaagacttacaaacgggagctttcgcacccc
ccattgtacagactgcctttgctagaaaatgcagaaactccgcaatga
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integrated database retrieval system
